Results 11 to 20 of about 555,224 (393)
Synaptic vesicle characterization of iPSC-derived dopaminergic neurons provides insight into distinct secretory vesicle pools. [PDF]
NPJ Parkinsons DisFujise K +3 more
europepmc +3 more sources
Synaptic vesicle endocytosis [PDF]
Current Opinion in Neurobiology, 1997 Exocytosis of synaptic vesicles is followed rapidly by reinternalization and recycling of their membranes. Recent studies have confirmed the key role of clathrin-mediated endocytosis in synaptic vesicle reformation and have identified new proteins that participate in this process.
CREMONA , OTTAVIO, DE CAMILLI P.
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Synaptic Vesicle Exocytosis [PDF]
Cold Spring Harbor Perspectives in Biology, 2011 Presynaptic nerve terminals release neurotransmitters by synaptic vesicle exocytosis. Membrane fusion mediating synaptic exocytosis and other intracellular membrane traffic is affected by a universal machinery that includes SNARE (for "soluble NSF-attachment protein receptor") and SM (for "Sec1/Munc18-like") proteins.
Thomas C, Südhof, Josep, Rizo
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TRPM7 is critical for short-term synaptic depression by regulating synaptic vesicle endocytosis
eLife, 2021 Transient receptor potential melastatin 7 (TRPM7) contributes to a variety of physiological and pathological processes in many tissues and cells. With a widespread distribution in the nervous system, TRPM7 is involved in animal behaviors and neuronal ...
Zhong-Jiao Jiang +10 more
doaj +1 more source
Synaptic Vesicle Endocytosis [PDF]
Cold Spring Harbor Perspectives in Biology, 2012 Neurons can sustain high rates of synaptic transmission without exhausting their supply of synaptic vesicles. This property relies on a highly efficient local endocytic recycling of synaptic vesicle membranes, which can be reused for hundreds, possibly thousands, of exo-endocytic cycles. Morphological, physiological, molecular, and genetic studies over
Yasunori, Saheki, Pietro, De Camilli
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Ion transport and regulation in a synaptic vesicle glutamate transporter
Science, 2020 Transport dependent on context Transporter proteins move substrates across a membrane, often coupling this activity to cellular ion concentration gradients.
Fei Li +11 more
semanticscholar +1 more source
A delay in vesicle endocytosis by a C-terminal fragment of N-cadherin enhances Aβ synaptotoxicity
Cell Death Discovery, 2023 Synaptotoxic Aβ oligomers are thought to play a major role in the early pathology of Alzheimer´s disease (AD). However, the molecular mechanisms involved in Aβ-induced synaptic dysfunction and synapse damage remain largely unclear.
Zenghui Teng +5 more
doaj +1 more source
Synaptic actions of amyotrophic-lateral-sclerosis-associated G85R-SOD1 in the squid giant synapse [PDF]
, 2020 © The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Song, Y.
Song, Yuyu
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Disorders of synaptic vesicle fusion machinery
Journal of Neurochemistry, 2020 The revolution in genetic technology has ushered in a new age for our understanding of the underlying causes of neurodevelopmental, neuromuscular and neurodegenerative disorders, revealing that the presynaptic machinery governing synaptic vesicle fusion ...
Holly Melland, Elysa Carr, S. Gordon
semanticscholar +1 more source
Localization and mobility of synaptic vesicles in Myosin VI mutants of Drosophila. [PDF]
PLoS ONE, 2014 BACKGROUND: At the Drosophila neuromuscular junction (NMJ), synaptic vesicles are mobile; however, the mechanisms that regulate vesicle traffic at the nerve terminal are not fully understood.
Marta Kisiel +2 more
doaj +1 more source