Results 11 to 20 of about 91,819 (309)
Synaptic vesicle endocytosis [PDF]
Exocytosis of synaptic vesicles is followed rapidly by reinternalization and recycling of their membranes. Recent studies have confirmed the key role of clathrin-mediated endocytosis in synaptic vesicle reformation and have identified new proteins that participate in this process.
Ottavio Cremona, Pietro De Camilli
exaly +4 more sources
Single vesicle tracking for studying synaptic vesicle dynamics in small central synapses
Sustained neurotransmission is driven by a continuous supply of synaptic vesicles to the release sites and modulated by synaptic vesicle dynamics. However, synaptic vesicle dynamics in synapses remain elusive because of technical limitations.
Chungwon Park +2 more
exaly +2 more sources
Communication between cells reaches its highest degree of specialization at chemical synapses. Some synapses talk in a 'whisper'; others 'shout'. The 'louder' the synapse, the more synaptic vesicles are needed to maintain effective transmission, ranging from a few hundred (whisperers) to nearly a million (shouters).
Silvio O, Rizzoli, William J, Betz
openaire +3 more sources
Synaptic Transmission: Kinetics of synaptic-vesicle recycling [PDF]
The kinetics of different steps in synaptic-vesicle recycling, including exocytosis, internalization and repriming, have recently been estimated in various types of living cell.
Betz, William J., Wu, Ling-Gang
openaire +3 more sources
Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming [PDF]
Ferenc Deak +2 more
exaly +2 more sources
Dynamic regulation of vesicle pools in a detailed spatial model of the complete synaptic vesicle cycle. [PDF]
Synaptic transmission is driven by a complex cycle of vesicle docking, release, and recycling, maintained by distinct vesicle pools. However, the partitioning of vesicle pools and reserve pool recruitment remain poorly understood.
Gallimore AR +4 more
europepmc +2 more sources
Mechanisms underlying allosteric modulation of antiseizure medication binding to synaptic vesicle protein 2A (SV2A). [PDF]
Mittal A +8 more
europepmc +3 more sources
Synaptic Vesicle Exocytosis [PDF]
Presynaptic nerve terminals release neurotransmitters by synaptic vesicle exocytosis. Membrane fusion mediating synaptic exocytosis and other intracellular membrane traffic is affected by a universal machinery that includes SNARE (for "soluble NSF-attachment protein receptor") and SM (for "Sec1/Munc18-like") proteins.
Thomas C, Südhof, Josep, Rizo
openaire +2 more sources
<p>This is the first stable release of recycled synaptic vesicle ISVE simulation code to model net retrograde flux</p ...
AU-Neurophysics-Lab
core +1 more source
The synaptic vesicle proteome [PDF]
AbstractSynaptic vesicles are key organelles in neurotransmission. Vesicle integral or membrane‐associated proteins mediate the various functions the organelle fulfills during its life cycle. These include organelle transport, interaction with the nerve terminal cytoskeleton, uptake and storage of low molecular weight constituents, and the regulated ...
Jacqueline, Burré, Walter, Volknandt
openaire +2 more sources

