Oligodendrocyte: Development, Plasticity, Biological Functions, Diseases, and Therapeutic Targets
MedComm, Volume 7, Issue 2, February 2026.The oligodendrocyte lineage and its roles in development, plasticity, and CNS homeostasis have been shown to have the potential to treat neurological diseases. However, the main obstacles to clinical translation, particularly in terms of BBB challenges and precise delivery.
Qiong Xiang +6 more
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Brain-Derived Neurotrophic Factor Trafficking via the Regulated Secretory Pathway: Mechanisms and Disease Implications. [PDF]
Mol NeurobiolEwell SN.
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The role of auditory sensory input during functional pre- and postsynaptic maturation of the calyx of Held synapse. [PDF]
, 2007 Erazo Fischer, E.
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Protein Science, Volume 35, Issue 2, February 2026.Abstract The misfolding and aggregation of α‐synuclein is a central molecular event in the etiology of Parkinson's disease and related disorders. α‐synuclein misfolding and pathology are both concentration‐dependent, but it is not clear precisely how changes in concentration alter the folding landscape within cells. Whereas most conventional structural
Daeun Noh, Robert W. Newberry
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Synaptic Vesicle Recycling Through the Lens of Ultrafast Endocytosis. [PDF]
Annu Rev NeurosciWatanabe S.
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Efficient and rapid isolation of native AMPA receptor complexes for cryo‐EM
Protein Science, Volume 35, Issue 2, February 2026.Abstract Isolating native ion channels for structural characterization is routinely achieved by extraction from membrane fractions of tissue with prolonged mild detergent treatment. AMPA receptors (AMPARs), glutamatergic receptors that mediate fast excitatory transmission and synaptic plasticity, are coassembled with diverse auxiliary subunits and ...
Jumi Park, Eric Gouaux
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Impact of SNAP-25 MnlI polymorphism on brain activity patterns in children with ADHD: Insights from fractional amplitude of low-frequency fluctuation analysis. [PDF]
Neuroimage RepFang D +6 more
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Bayesian Inference via GeTex‐OTS Based Stochastic Synapse for Uncertainty‐Aware Medical Diagnostics
SmartMat, Volume 7, Issue 1, February 2026.This work reports a GeTex ovonic threshold switch integrated into a compact 1S1T1R stochastic synapse that directly realizes an MC‐Dropconnect Bayesian neural network. Tunable probabilistic switching enables uncertainty‐aware COVID‐19 diagnosis and MNIST recognition while remaining compatible with conventional 1T1R CIM architectures, highlighting a ...
Xinyu Wen +9 more
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An ArfGAP-dependent signaling modulates synaptic plasticity via IP3-regulated calcium release from the endoplasmic reticulum. [PDF]
PLoS GenetMallik B +5 more
europepmc +1 more source
Amyloid-ß Acts as a regulator of neurotransmitter release disrupting the interaction between synaptophysin and VAMP2 [PDF]
Alifragis, P +5 more
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