Results 141 to 150 of about 63,572 (265)
Synaptogenesis is encoded by multiple genes that program the assembly of neural networks in the immature brain during development and later in life, in the experienced brain that must respond to changes of the external world and of proprioception. Processing of neural network activity cannot solely rely on the activity of established synapses as their ...
Jeanneteau, Freddy +2 more
openaire +1 more source
Figure 1 visually summarizes the core biological functions and therapeutic potential of the HGF/c‐Met signaling axis. Abstract Hepatocyte growth factor (HGF) is a multifunctional cytokine that activates the tyrosine kinase activity of its specific receptor, c‐Met (mesenchymal–epithelial transition factor).
Hongqin Sun +7 more
wiley +1 more source
Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad +12 more
wiley +1 more source
EEG Dynamics in Children Before, During and After General Anesthesia
ABSTRACT Background Age‐specific EEG signatures during anesthesia are described in pediatrics, and perioperative monitoring is increasingly advocated; yet most indices and algorithms derive from adult data and may not generalize to early development. Aims The purpose of this study was to characterize perioperative frontal EEGs in young children younger
Maximilian Markus +3 more
wiley +1 more source
Abstract Background and aims Tobacco smoking is a major risk factor for cardiovascular and lung diseases. A better understanding of its neurobiological underpinnings will benefit the prevention of smoking‐related illnesses and mortality. Previous studies link smoking to increased iron concentration in the striatum, a central component of the brain's ...
Olga Trofimova +2 more
wiley +1 more source
Gestational kynurenine metabolites mediate effects of pregnancy adiposity on child negative affect
Background Mounting evidence links increased adiposity during pregnancy and offspring risk for mental health disorders. Yet the mechanisms underlying this association remain poorly understood, limiting our ability to design effective interventions.
Hanna C. Gustafsson +4 more
wiley +1 more source
Background Anorexia nervosa (AN) is a severe eating disorder associated with drastic reductions in gray and white matter (WM) volume and structural connectivity alterations. However, the hypotheses regarding underlying mechanisms are inconclusive. The current study investigated the relationships of WM volume as well as WM network architecture with ...
Inger Hellerhoff +10 more
wiley +1 more source
xx xx. ABSTRACT Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by disrupted neuronal circuit maturation. Emerging evidence implicates microglial function and mitochondrial regulation as contributors to ASD‐associated biology, yet the mechanisms linking these processes to neuronal development remain poorly defined ...
Sydney P. Sterben +4 more
wiley +1 more source
Human metabolic adaptations and prolonged expensive neurodevelopment: A review [PDF]
1. After weaning, human hunter-gatherer juveniles receive substantial (≈3.5-7 MJ day^-1^), extended (≈15 years) and reliable (kin and nonkin food pooling) energy provision. 2. The childhood (pediatric) and the adult human ...
John R. Skoyles
core +3 more sources
This study presents a wireless, non‐invasive strategy for neural repair by developing a biodegradable piezoelectric dural patch that, under transcranial ultrasound, generates localized electrical fields to drive endogenous neural stem cells toward neuronal differentiation and functional integration.
Pengbo Zhou +7 more
wiley +1 more source

