Results 121 to 130 of about 44,470 (243)

Frozen in Place: Proximity Labeling Maps Glial Interactomes Across Cell States

Glia, Volume 74, Issue 10, October 2026.
Proximity labeling enables cell‐type‐specific and spatially resolved mapping of glial protein networks. Proximity labeling approaches provide insights into glial function under physiological and pathological conditions. ABSTRACT Glial cells, including radial glia, oligodendrocyte precursor cells (OPCs), oligodendrocytes, astrocytes, and microglia, are ...
João Baltar, Rebecca Abati, Luísa Florido, Matthew G. Holt   +3 more
wiley   +1 more source

GABAergic integration of transient and persistent neurons in the developing mouse somatosensory cortex

Frontiers in Cellular Neuroscience
GABA is an essential element in the function of neocortical circuits. The origin, migration and mechanisms of synaptogenesis of GABAergic neurons have been intensively studied.
Ahd Abusaada, Federico De Rosa, Heiko J. Luhmann, Werner Kilb, Anne Sinning   +4 more
doaj   +1 more source

Charting the Normal Development of Structural Brain Connectivity in Utero Using Diffusion MRI

Human Brain Mapping, Volume 47, Issue 14, October 1, 2026.
This study proposes new methods to study the development of the structural connectivity in utero using diffusion‐weighted MRI. The methods are applied on data from around 200 fetal brains to chart how the structural connectome develops between 22 and 37 gestational weeks.
Davood Karimi, Bo Li, Athena Taymourtash, Camilo Jaimes, P. Ellen Grant, Simon K. Warfield   +5 more
wiley   +1 more source

Both Genetic Manipulation and Acupuncture Alleviate Depressive‐Like Behavior Mediated by Astrocytic P2X7 Receptors

MedComm, Volume 7, Issue 10, October 2026.
The efficacy of the chronic unpredictable mild stress (CUMS) model in mice was assessed using the tail suspension test (TST; A) and the forced swim test (FST; B). In both major depressive disorder (MDD) mouse models, CUMS significantly increased immobility time, indicating the development of depressive‐like behavior.
Wen‐Jing Ren, Muhammad Tahir Khan, Xing‐Ying Ren, Xuan Li, Patrizia Rubini, Hai‐Yan Yin, Alexei Verkhratsky, Peter Illes, Yong Tang   +8 more
wiley   +1 more source

Cancer Neuroscience: From Hallmark‐Enabling Biology to a Therapeutic Pillar

Advanced Oncology, Volume 1, Issue 1, December 2026.
Moran Amit
wiley   +1 more source

Diving Deeper Into Mechanisms of Acrylamide‐Induced Toxicity: RNA Sequencing Reveals Transcriptomic Alteration and Retrotransposon Expression in Drosophila melanogaster

Environmental Toxicology, Volume 41, Issue 10, Page 1105-1118, October 2026.
ABSTRACT Given the inevitability of human and animal exposure to acrylamide, there is increasing concern regarding its potential health risks. While a number of molecular mechanisms have been proposed, the complexity of acrylamide toxicological pathways and interactions remains incompletely characterized.
Oluwabukola Mary Farodoye, Titilayomi Ayomide Otenaike, Daniela Moreira Mombach, Monica Medeiros Silva, Amos Olalekan Abolaji, Elgion Lucio Da Silva Loreto   +5 more
wiley   +1 more source

Emerging roles for Hox proteins in synaptogenesis.

, 2018
Neural circuit formation requires the intricate orchestration of multiple developmental events including cell fate specification, cell migration, axon guidance, dendritic growth, synaptic target selection, and synaptogenesis.
Gofflot, Françoise, Lizen Benoît
core  

Inhibition of leucine‐rich kinase 2 (LRRK2) promotes peripheral axon regeneration via phosphorylation‐network remodelling

British Journal of Pharmacology, Volume 183, Issue 20, Page 6199-6224, October 2026.
Background and Purpose In contrast to neurons in the central nervous system, neurons in the peripheral nervous system can regenerate axons after injury via activation of a pro‐regenerative transcriptional programme. Pathogenic mutations in leucine‐rich repeat kinase 2 (LRRK2) are the most common genetic cause of Parkinson's disease, and several small ...
Eun‐Hae Jang, Eun Mo Yang, Gil Song, Seung Min Park, Harryn Choi, Jaeyong Kim, Chanil Kim, Yunho Gim, Hyuk‐Joo Jeon, Yewon Cho, Jong Bae Park, Eun‐Mi Hur   +11 more
wiley   +1 more source

Reln Haploinsufficiency Enhances Fentanyl‐Induced Locomotion and Dorsal Striatal Activity Without Affecting Opioid Reinforcement and Relapse‐Like Behavior

Genes, Brain and Behavior, Volume 25, Issue 5, October 2026.
Reln haploinsufficiency does not alter fentanyl self‐administration, relapse‐like seeking, or conditioned place preference in mice. Instead, reduced Reln expression selectively enhances acute fentanyl‐induced locomotion and dorsal striatal Fos activation, positioning Reelin as a modulator of opioid‐evoked neuronal activity rather than opioid ...
Carl Litif, Avraham M. Libster, Shane Desfor, Tanieng Huang, Leanne Liaw, Annika Cheng, Francesca Telese   +6 more
wiley   +1 more source

Investigating the role of SORBS1 in synaptogenesis

, 2018
Synaptogenesis is an exquisite process in which synaptic contacts establish between neurons. The locations, numbers and types of synapses are under precise regulation during synaptogenesis, to ensure the homeostasis of nervous system is maintained.
Cai, Songchen
core