Results 81 to 90 of about 13,926 (184)

Adrenal Steroids Modulate Fibroblast-Like Synoviocytes Response During B. abortus Infection

Frontiers in Endocrinology, 2019
Brucella abortus stimulates an inflammatory immune response that stimulates the endocrine system, inducing the secretion of dehydroepiandrosterone (DHEA) and cortisol. In humans, the active disease is generally present as osteoarticular brucellosis.
María Virginia Gentilini, Guillermo Hernán Giambartolomei, María Victoria Delpino   +2 more
doaj   +1 more source

Dermal Fibroblasts, Not Keratinocytes, Dominate IL‐17A/TNF‐Driven Inflammation

Experimental Dermatology, Volume 35, Issue 3, March 2026.
ABSTRACT Chronic inflammatory skin diseases such as psoriasis and hidradenitis suppurativa are driven by cytokines, including IL‐17A and TNF. Although biologics targeting these cytokines have transformed therapy, the transcriptional contributions of individual skin‐resident cell types remain unclear, and dermal fibroblasts have been largely overlooked ...
Lejla Svraka, Hakim Ben Abdallah, Trine Bertelsen, Christian Vestergaard, Claus Johansen   +4 more
wiley   +1 more source

Oxygen and indocyanine green loaded phase-transition nanoparticle-mediated photo-sonodynamic cytotoxic effects on rheumatoid arthritis fibroblast-like synoviocytes

International Journal of Nanomedicine, 2017
Qin Tang,1–3 Jianyu Cui,1 Zhonghua Tian,1 Jiangchuan Sun,4 Zhigang Wang,2 Shufang Chang,4 Shenyin Zhu1 1Department of Pharmacy, First Affiliated Hospital of Chongqing Medical University, 2Department of Ultrasound, Institute of Ultrasound Imaging ...
Tang Q, Cui J, Tian Z, Sun J, Wang Z, Chang S, Zhu S   +6 more
doaj  

Pooled Platelet-Rich Plasma Lysate Therapy Increases Synoviocyte Proliferation and Hyaluronic Acid Production While Protecting Chondrocytes From Synoviocyte-Derived Inflammatory Mediators

Frontiers in Veterinary Science, 2018
Platelet-rich plasma (PRP) preparations are being used with moderate success to treat osteoarthritis (OA) in humans and in veterinary species. Such preparations are hindered, however, by being autologous in nature and subject to tremendous patient and ...
Jessica M. Gilbertie, Jessica M. Gilbertie, Julie M. Long, Alicia G. Schubert, Alix K. Berglund, Alix K. Berglund, Thomas P. Schaer, Lauren V. Schnabel, Lauren V. Schnabel   +8 more
doaj   +1 more source

The emerging fibroblast‐like synoviocyte channelome [PDF]

Experimental Physiology, 2018
Simon R. Tew, Richard Barrett‐Jolley
openaire   +3 more sources

Additive or Synergistic Interactions Between IL-17A or IL-17F and TNF or IL-1β Depend on the Cell Type

Frontiers in Immunology, 2019
Background: IL-17A has effects on several cell types and is a therapeutic target in several inflammatory diseases. IL-17F shares 50% homology and biological activities with IL-17A. It is now of interest to target both cytokines.
Mélissa Noack, Audrey Beringer, Pierre Miossec   +2 more
doaj   +1 more source

PO:01:014 | Differential inflammatory responses of CD14+ and CD14– synoviocytes in psoriatic arthritis: implications for pathogenesis and targeted therapies

Reumatismo
Background. Investigating the inflammatory response of synoviocytes in patients with psoriatic arthritis (PsA) is crucial due to their central role in disease pathogenesis. Recent studies have reported upregulation of interleukin-6 (IL-6) and activation
Società Italiana di Reumatologia
doaj  

IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes

Experimental and Molecular Medicine, 2019
IRF-1: a key regulator in rheumatoid Arthritis Thomas Karonitsch at the Medical University of Vienna, Austria, and colleagues showed that activation of the protein interferon regulatory factor 1 (IRF-1) in human synoviocytes promoted the expression of ...
Michael Bonelli, Karolina Dalwigk, Alexander Platzer, Isabel Olmos Calvo, Silvia Hayer, Birgit Niederreiter, Johannes Holinka, Florian Sevelda, Thomas Pap, Günter Steiner, Giulio Superti-Furga, Josef S. Smolen, Hans P. Kiener, Thomas Karonitsch   +13 more
doaj   +1 more source

Synoviocytes [PDF]

Journal of Clinical Pathology, 1978
openaire   +3 more sources

Osteopontin inhibits autophagy via CD44 and avβ3 integrin and promotes cell proliferation in osteoarthritic fibroblast-like synoviocytes

BMC Musculoskeletal Disorders
Objective Osteoarthritis (OA) is closely related to aging, and autophagy is implicated in the retardation of aging. Activated synoviocytes play important roles in OA; the synoviocytes could produce osteopontin (OPN) and its main receptors CD44 and ...
Min Li, Chang-Bao Wei, Hai-Feng Li, Ke He, Rui-Jun Bai, Fang-Jie Zhang   +5 more
doaj   +1 more source