m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang +18 more
wiley +1 more source
Development of Arginine Stearate-Based Solid Lipid Nanoparticles for Enhanced Idebenone Delivery: In Vitro Evaluation on Glioblastoma Model. [PDF]
Petralito S +7 more
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In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun +15 more
wiley +1 more source
Microbial partnerships and molecular mechanisms in plant stress physiology for climate-resilient and sustainable farming. [PDF]
Gelaw TA +8 more
europepmc +1 more source
Better synthetic biology outcomes through balanced push-pull engineering. [PDF]
Reyes-Hernández BJ.
europepmc +1 more source
Synthesis, Characterization, Molecular Docking Study and Biological Evaluation of Novel 1,3,4-Thiadiazole-Based Heterocycles as Potential Anticancer and Antioxidant Agents. [PDF]
El-Metwaly NM +7 more
europepmc +1 more source
From Aryltetralin Anticancer Scaffolds to Host-Directed Bioactivities: A Mechanism-Based Review of Lignans and Neolignans. [PDF]
Xie Y, Tang K, Coghi P.
europepmc +1 more source
Simplified synthesis of anti-oxidant small molecule <sup>OH</sup>PyN<sub>3</sub>. [PDF]
Mingle D, Kumar N, Green KN.
europepmc +1 more source
Integrated Phytochemical and Pharmacological Insights into <i>Premna serratifolia</i> for Drug Discovery: A Narrative Review. [PDF]
Ariyanto A +5 more
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