Results 11 to 20 of about 198,272 (298)
Characterization of M11-like and OC125-like Monoclonal Antibody Binding to CA125 Tandem Repeats [PDF]
BiosensorsThe CA125 epitope within the MUC16 tandem repeat region is detected via the CA125 II test for ovarian cancer surveillance. This test utilizes the M11 and OC125 antibodies.
Trisha Nair +6 more
doaj +2 more sources
Genome-wide selection inference at short tandem repeats. [PDF]
PLoS GeneticsShort tandem repeats (STRs) comprising repeated sequences of 1-6 bp are one of the largest sources of genetic variation in humans. STRs are known to contribute to a variety of disorders, including Mendelian diseases, complex traits, and cancer.
Bonnie Huang +6 more
doaj +2 more sources
TRFill: synergistic use of HiFi and Hi-C sequencing enables accurate assembly of tandem repeats for population-level analysis [PDF]
Genome BiologyThe highly repetitive content of eukaryotic genomes, including long tandem repeats, segmental duplications, and centromeres, makes haplotype-resolved genome assembly hard. Repeat sequences introduce gaps or mis-joins in the assemblies.
Huaming Wen +10 more
doaj +2 more sources
Structured Tandem Repeats in Protein Interactions [PDF]
International Journal of Molecular SciencesTandem repeats (TRs) in protein sequences are consecutive, highly similar sequence motifs. Some types of TRs fold into structural units that pack together in ensembles, forming either an (open) elongated domain or a (closed) propeller, where the last unit of the ensemble packs against the first one.
Juan Mac Donagh +9 more
openaire +4 more sources
Scientific Reports, 2021 Infections due to triazole-resistant Aspergillus fumigatus are increasingly reported worldwide and are associated with treatment failure and mortality. The principal class of azole-resistant isolates is characterized by tandem repeats of 34 bp or 46 bp ...
Plinio Trabasso +6 more
doaj +1 more source
Insight into role of selection in the evolution of polyglutamine tracts in humans. [PDF]
PLoS ONE, 2012 Glutamine tandem repeats are common in eukaryotic proteins. Although some studies have proposed that replication slippage plays an important role in shaping these repeats, the role of natural selection in glutamine tandem repeat evolution is somewhat ...
Hongwei Li +3 more
doaj +1 more source
Biomolecules, 2015 The NOD-like receptors (NLRs) and Toll-like receptors (TLRs) are pattern recognition receptors that are involved in the innate, pathogen pattern recognition system.
Norio Matsushima +3 more
doaj +1 more source
TRDB--The Tandem Repeats Database [PDF]
Nucleic Acids Research, 2007 Tandem repeats in DNA have been under intensive study for many years, first, as a consequence of their usefulness as genomic markers and DNA fingerprints and more recently as their role in human disease and regulatory processes has become apparent. The Tandem Repeats Database (TRDB) is a public repository of information on tandem repeats in genomic DNA.
Gelfand, Yevgeniy +2 more
openaire +3 more sources
Comparative Analysis of Tandem Repeats from Hundreds of Species Reveals Unique Insights into Centromere Evolution [PDF]
, 2012 Centromeres are essential for chromosome segregation, yet their DNA sequences evolve rapidly. In most animals and plants that have been studied, centromeres contain megabase-scale arrays of tandem repeats.
Bradnam, Keith R. +16 more
core +4 more sources
TRAL: tandem repeat annotation library [PDF]
Bioinformatics, 2015 Abstract Motivation: Currently, more than 40 sequence tandem repeat detectors are published, providing heterogeneous, partly complementary, partly conflicting results. Results: We present TRAL, a tandem repeat annotation library that allows running and parsing of various detection outputs, clustering of redundant or ...
Schaper, Elke +8 more
openaire +5 more sources