Results 21 to 30 of about 2,826 (173)

Regulating Integrin β1 to Restore Gonadotropin-Releasing Hormone–Tanycyte Unit Function in Polycystic Ovary Syndrome-Related Hypothalamic Dysregulation [PDF]

Research
Excessive gonadotropin-releasing hormone (GnRH) is considered to be an initiating factor in the etiology of polycystic ovary syndrome (PCOS). GnRH neuronal axons terminate at the hypothalamic arcuate nucleus and median eminence, where tanycytes ...
Yu Wang, Xiaoyu Tong, Yan Xiao, Yicong Wang, Wei Hu, Wenhan Lu, Yuning Chen, Jiajia Li, Wenhao Gao, Hongru Gao, Yicheng Tian, Sizhe Dai, Yi Feng   +12 more
doaj   +2 more sources

Tanycytes release glucose using the glucose-6-phosphatase system during hypoglycemia to control hypothalamic energy balance

Molecular Metabolism
Objective: The liver releases glucose into the blood using the glucose-6-phosphatase (G6Pase) system, a multiprotein complex located in the endoplasmic reticulum (ER).
María José Barahona, Luciano Ferrada, Matías Vera, Francisco Nualart   +3 more
doaj   +2 more sources

Regulation of thyroid hormone gatekeepers by TSH in tanycytes.

Thyroid®
International audienceBackground: Tanycytes are specialized glial cells within the mediobasal hypothalamus that have multiple functions, including hormone sensing and regulation of hypophysiotropic hormone secretion.
Neve, V., Spiecker, F., Prevot, Vincent, Müller-Fielitz, H., Chandrasekar, A., Gauthier, Karine, Rivagorda, M., Schwaninger, M., Schmidtlein, P. M.   +8 more
core   +4 more sources

Tanycyte, the neuron whisperer

Physiology & Behavior, 2023
Reciprocal communication between neurons and glia is essential for normal brain functioning and adequate physiological functions, including energy balance. In vertebrates, the homeostatic process that adjusts food intake and energy expenditure in line with physiological requirements is tightly controlled by numerous neural cell types located within the
Dali, Rafik, Estrada-Meza, Judith, Langlet, Fanny   +2 more
openaire   +4 more sources

Perspective: rheostasis revisited-hibernation and tanycytes. [PDF]

J Comp Physiol B
Abstract Mammalian hibernation is a physiological and behavioural adaptation that permits survival during seasonal periods of energy shortage via a combination of pre-hibernal energy storage and hibernal metabolic depression (torpor).
Wood SH.
europepmc   +3 more sources

Loss of Function of the Neural Cell Adhesion Molecule NrCAM Regulates Differentiation, Proliferation and Neurogenesis in Early Postnatal Hypothalamic Tanycytes

Frontiers in Neuroscience, 2022
Hypothalamic tanycytes are neural stem and progenitor cells, but little is known of how they are regulated. Here we provide evidence that the cell adhesion molecule, NrCAM, regulates tanycytes in the adult niche.
Alex Moore, Alex Moore, Alex Moore, Kavitha Chinnaiya, Kavitha Chinnaiya, Kavitha Chinnaiya, Dong Won Kim, Sarah Brown, Sarah Brown, Sarah Brown, Iain Stewart, Iain Stewart, Iain Stewart, Sarah Robins, Sarah Robins, Sarah Robins, Georgina K. C. Dowsett, Georgina K. C. Dowsett, Charlotte Muir, Marco Travaglio, Jo E. Lewis, Jo E. Lewis, Fran Ebling, Seth Blackshaw, Seth Blackshaw, Seth Blackshaw, Seth Blackshaw, Seth Blackshaw, Andrew Furley, Andrew Furley, Andrew Furley, Marysia Placzek, Marysia Placzek, Marysia Placzek   +33 more
doaj   +1 more source

Tanycytes: bloodhounds of the metabolic brain. [PDF]

Trends Endocrinol Metab
Constant monitoring and fine-tuning of internal body status to maintain energy homeostasis despite changing physiological needs and environmental conditions are essential brain functions. Hypothalamic tanycytes - specialized ependymoglial cells at the interface between the blood and the brain - play crucial roles in this regulation through mechanisms ...
Rodriguez-Cortes B, Gomez-Martínez R, Spenle R, Schwaninger M, Nogueiras R, Rasika S, Prevot V.   +6 more
europepmc   +3 more sources

Txnip, Tanycytes, and Torpor [PDF]

Endocrinology, 2013
As biologists, we are brought up with the concept that mammals are homeothermic, so they tightly regulate body temperature through a complex balance between thermogenesis and heat conservation and dissipation mechanisms. One of the remarkable features of the natural world is that many mammals can also show torpor or hibernation.
Francis J P, Ebling, Ricardo, Samms
openaire   +2 more sources

A Glial-Neuronal Circuit in the Median Eminence Regulates Thyrotropin-Releasing Hormone-Release via the Endocannabinoid System

iScience, 2020
Summary: Based on the type-I cannabinoid receptor (CB1) content of hypophysiotropic axons and the involvement of tanycytes in the regulation of the hypothalamic-pituitary-thyroid (HPT) axis, we hypothesized that endocannabinoids are involved in the ...
Erzsébet Farkas, Edina Varga, Balázs Kovács, Anett Szilvásy-Szabó, Antonieta Cote-Vélez, Zoltán Péterfi, Magdalini Matziari, Mónika Tóth, Dóra Zelena, Zsolt Mezriczky, Andrea Kádár, Dóra Kővári, Masahiko Watanabe, Masanobu Kano, Ken Mackie, Balázs Rózsa, Yvette Ruska, Blanka Tóth, Zoltán Máté, Ferenc Erdélyi, Gábor Szabó, Balázs Gereben, Ronald M. Lechan, Jean-Louis Charli, Patricia Joseph-Bravo, Csaba Fekete   +25 more
doaj   +1 more source

Tanycytic ependymoma

Indian Journal of Pathology and Microbiology, 2021
Background: Tanycytic ependymoma (TE) (WHO grade II) is a rare and morphologically distinct variant of ependymoma with only 77 cases reported worldwide so far. Variable clinical and radio-pathological features lead to misdiagnosis as WHO grade 1 tumors. On imaging, differentials of either schwannoma, meningioma, low-grade glial
Pragya, Jain, Ravindra K, Saran, Daljit, Singh, Anita, Jagetia, A K, Srivastava, Hukum, Singh   +5 more
openaire   +2 more sources