Results 51 to 60 of about 2,826 (173)

Tanycytes control hypothalamic liraglutide uptake and its anti-obesity actions

open access: yes, 2022
Liraglutide, an anti-diabetic drug and agonist of the glucagon-like peptide one receptor (GLP1R), has recently been approved to treat obesity in individuals with or without type 2 diabetes. Despite its extensive metabolic benefits, the mechanism and site
Saponaro, Chiara   +33 more
core   +1 more source

When a Little Bit More Makes the Difference: Expression Levels of GKRP Determines the Subcellular Localization of GK in Tanycytes

open access: yesFrontiers in Neuroscience, 2019
Glucose homeostasis is performed by specialized cells types that detect and respond to changes in systemic glucose concentration. Hepatocytes, β-cells and hypothalamic tanycytes are part of the glucosensor cell types, which express several proteins ...
Magdiel Salgado   +5 more
doaj   +1 more source

A simple strategy for culturing morphologically-conserved rat hypothalamic tanycytes [PDF]

open access: yes, 2023
Hypothalamic tanycytes are specialized bipolar ependymal cells that line the floor of the third ventricle. Given their strategic location, tanycytes are believed to play several key functions including being a selective barrier and controlling the amount
Perelló, Mario Carlos   +6 more
core  

Purinergic signaling in tanycytes and its contribution to nutritional sensing

open access: yes, 2021
Tanycytes are hypothalamic radial glial-like cells with an important role in the regulation of neuroendocrine axes and energy homeostasis. These cells have been implicated in glucose, amino acids, and fatty acid sensing in the hypothalamus of rodents ...
Sáez, Juan C.   +2 more
core   +1 more source

Replication Data for: Hypothalamic tanycytes as mediators of maternally programmed seasonal plasticity

open access: yes, 2023
The following data is provided to support the publication: "Hypothalamic tanycytes as mediators of maternally programmed seasonal plasticity". The data provided are body and testis weight for phodopus sungorus raised on different photoperiods, the genome
Hazlerigg, David   +8 more
core   +1 more source

Synchronous presentation of prolactinoma and supratentorial tanycytic ependymoma

open access: yesJournal of Neurosciences in Rural Practice, 2023
Tanycytic ependymomas mostly occur in the spinal cord and it is the rarest histological subtype of ependymoma. A 29-year-old male was referred from the infertility clinic after serum prolactin levels were found to be elevated. Magnetic resonance imaging (MRI) brain showed an irregular necrotic lesion in the periventricular region of the left parietal ...
Nair, Jishnu Narayanan   +3 more
openaire   +2 more sources

Blockade of Glial Connexin 43 Hemichannels Reduces Food Intake

open access: yesCells, 2020
The metabolic syndrome, which comprises obesity and diabetes, is a major public health problem and the awareness of energy homeostasis control remains an important worldwide issue. The energy balance is finely regulated by the central nervous system (CNS)
Florent Guillebaud   +10 more
doaj   +1 more source

Adenovirus-mediated suppression of hypothalamic glucokinase affects feeding behavior

open access: yesScientific Reports, 2017
Glucokinase (GK), the hexokinase involved in glucosensing in pancreatic β-cells, is also expressed in arcuate nucleus (AN) neurons and hypothalamic tanycytes, the cells that surround the basal third ventricle (3V).
Romina María Uranga   +10 more
doaj   +1 more source

A sweet taste receptor-dependent mechanism of glucosensing in hypothalamic tanycytes [PDF]

open access: yes, 2017
Hypothalamic tanycytes are glial-like glucosensitive cells that contact the cerebrospinal fluid of the third ventricle, and send processes into the hypothalamic nuclei that control food intake and body weight.
Benford, Heather   +18 more
core   +1 more source

Connexin-43 Gap Junctions Are Responsible for the Hypothalamic Tanycyte-Coupled Network

open access: yesFrontiers in Cellular Neuroscience, 2018
Tanycytes are hypothalamic radial glia-like cells that form the basal wall of the third ventricle (3V) where they sense glucose and modulate neighboring neuronal activity to control feeding behavior.
Antonia Recabal   +11 more
doaj   +1 more source

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