Results 61 to 70 of about 2,826 (173)

Ciliary Neurotrophic Factor Acts on Distinctive Hypothalamic Arcuate Neurons and Promotes Leptin Entry Into and Action on the Mouse Hypothalamus

Frontiers in Cellular Neuroscience, 2020
In humans and experimental animals, the administration of ciliary neurotrophic factor (CNTF) reduces food intake and body weight. To gain further insights into the mechanism(s) underlying its satiety effect, we: (i) evaluated the CNTF-dependent ...
Wiebe Venema, Ilenia Severi, Jessica Perugini, Eleonora Di Mercurio, Marco Mainardi, Margherita Maffei, Saverio Cinti, Saverio Cinti, Antonio Giordano   +8 more
doaj   +1 more source

Anatomical Organization of the Rat Subfornical Organ

Frontiers in Cellular Neuroscience, 2021
The subfornical organ (SFO) is a sensory circumventricular organ located along the anterodorsal wall of the third ventricle. SFO lacks a complete blood-brain barrier (BBB), and thus peripherally-circulating factors can penetrate the SFO parenchyma. These
Amirah-Iman Hicks, Simona Kobrinsky, Suijian Zhou, Jieyi Yang, Masha Prager-Khoutorsky   +4 more
doaj   +1 more source

Fabrication and characterisation of random and aligned electrospun scaffolds to investigate hypothalamic stem/progenitor cell behaviour

Engineered Regeneration
Tanycytes are stem/progenitor cells that reside in the hypothalamus of the adult vertebrate brain. Tanycytes can be cultured as free-floating neurospheres in vitro but tend to spontaneously differentiate over time.
Selina Beal, Iain Stewart, Paul Hatton, Marysia Placzek, Ilida Ortega   +4 more
doaj   +1 more source

Hypothalamic tanycytes internalize ghrelin from the cerebrospinal fluid: Molecular mechanisms and functional implications. [PDF]

Mol Metab
Objective The peptide hormone ghrelin exerts potent effects in the brain, where its receptor is highly expressed. Here, we investigated the role of hypothalamic tanycytes in transporting ghrelin across the blood-cerebrospinal fluid (CSF) interface ...
Gomez IM, Uriarte M, Fernandez G, Barrile F, Castrogiovanni D, Cantel S, Fehrentz JA, De Francesco PN, Perello M.   +8 more
europepmc   +2 more sources

Imaging features of spinal tanycytic ependymoma

The Neuroradiology Journal, 2016
Tanycytic ependymoma is an unusual morphological variant of WHO grade II ependymoma, typically arising from the cervical or thoracic spinal cord. Although the literature deals extensively with pathological features of this tumour entity, imaging features have not been well characterised.
Tomek, M, Jayajothi, A, Brandner, S, Jaunmuktane, Z, Lee, CH, Davagnanam, I   +5 more
openaire   +4 more sources

Purinergic signaling in hypothalamic tanycytes : potential roles in chemosensing

, 2011
Hypothalamic tanycytes are cells that line the walls of the 3rd ventricle. Their cell bodies contact the cerebrospinal fluid and give rise to an inwardly directed process.
Dale, Nicholas, Nicholas Dale
core   +1 more source

Tanycytes As Regulators of Seasonal Cycles in Neuroendocrine Function [PDF]

Frontiers in Neurology, 2017
Annual cycles of physiology and behavior are highly prevalent in organisms inhabiting temperate and polar regions. Examples in mammals include changes in appetite and body fat composition, hibernation and torpor, growth of antlers, pelage and horns, and seasonal reproduction.
Lewis, Jo E., Ebling, Francis J. P.
openaire   +2 more sources

Presentation_1_Selective Depletion of Adult GFAP-Expressing Tanycytes Leads to Hypogonadotropic Hypogonadism in Males.pptx

, 2022
In adult mammals, neural stem cells are localized in three neurogenic regions, the subventricular zone of the lateral ventricle (SVZ), the subgranular zone of the dentate gyrus of the hippocampus (SGZ) and the hypothalamus. In the SVZ and the SGZ, neural
Pascal Vaudin (12247568), Delphine Pillon (12247571), Martine Migaud (45450), Vincent Prévot (5655265), Ariane Sharif (8474172), Martine Batailler (5334), Valérie Leysen (12247565), Lucile Butruille (12247559), Marie-Line Cateau (12247562)   +8 more
core   +1 more source

Differential distribution of tight junction proteins suggests a role for tanycytes in blood-hypothalamus barrier regulation in the adult mouse brain.: Tanycytes at the blood-hypothalamus interface

, 2010
International audienceThe median eminence is one of the seven so-called circumventricular organs. It is located in the basal hypothalamus, ventral to the third ventricle and adjacent to the arcuate nucleus.
Bouret, Sébastien, G., Mullier, Amandine, Prevot, Vincent, Dehouck, Bénédicte   +3 more
core   +1 more source

Glial Endozepines Inhibit Feeding-Related Autonomic Functions by Acting at the Brainstem Level

Frontiers in Neuroscience, 2017
Endozepines are endogenous ligands for the benzodiazepine receptors and also target a still unidentified GPCR. The endozepine octadecaneuropeptide (ODN), an endoproteolytic processing product of the diazepam-binding inhibitor (DBI) was recently shown to ...
Florent Guillebaud, Clémence Girardet, Anne Abysique, Stéphanie Gaigé, Rym Barbouche, Jérémy Verneuil, André Jean, Jérôme Leprince, Marie-Christine Tonon, Michel Dallaporta, Bruno Lebrun, Jean-Denis Troadec   +11 more
doaj   +1 more source