Results 131 to 140 of about 49,724 (234)

The twin arginine translocase pathway : a functional and structural study in Escherichia coli and Synechocystis sp. PCC6803 [PDF]

The bacterial twin-arginine translocase (Tat) pathway is able to export large folded proteins across the cytoplasmic membrane. It derives its name from the almost invariant twin-arginine motif present in the signal peptide of Tat substrates.
Warren, Gemma Zara Louise
core  

The effect of methylation and oxidation at CpG locus 5 bases upstream of TATA-box on MeCP2 binding.

, 2014
In vitro binding of nuclear protein from HeLa cells to TATA-box and CpGs 5 bases upstream of TATA-box was tested by EMSA. (A) Double-stranded oligonucleotides, unmethylated (UUS/UUA), hemimethylated (UUS/UMA), single-methylated (UMS/UMA), and ...
Yasuhiro Minami (87853), Riko Kitazawa (600865), Michiru Nishida (600868), Yutaka Takahashi (600869), Sohei Kitazawa (147162), Ryuma Haraguchi (134976), Michiko Mori (528838), Takeshi Kondo (600866), Yasuhiro Hamada (600867), Kiyoshi Mori (289003)   +9 more
core   +1 more source

Conserved DNA-protein contacts formed by TATA-box binding proteins

, 2016
TATA-box binding proteins (TBPs) are components of multiprotein complexes known as TFIID1. These complexes take part in transcription initiation of many genes of Archaea and Eukaryota. TBPs are two-domain proteins, 179–187 amino acid residues in length.
Zanegina, Olga, Aksianov, Evgeniy, Alexeevski, Andrei V., Karyagina, Anna, Spirin, Sergei   +4 more
openaire   +1 more source

The Advantaged Salt Inducible Suaeda salsa SsNRT2.5 and Its Promoter Significantly Enhance Nitrate Transport Efficiency and Salt Tolerance in Transgenic Arabidopsis and Rice

Plant Biotechnology Journal, Volume 24, Issue 6, Page 4084-4101, June 2026.
ABSTRACT Efficient nitrogen (N) uptake is critical for crop yield, but soil salinization inhibits plant nitrogen acquisition. In this study, the nitrate (NO3−) transporter gene SsNRT2.5 and its promoter from the halophyte Suaeda salsa was investigated to elucidate the functional role in NO3− transport under salinity and low NO3−–N conditions.
Ranran Liu, Chenyang Li, Runtai Zhao, Congcong Song, Yan Zhou, Ruxin Zhao, Na Sui, Lei Wang, Jie Song   +8 more
wiley   +1 more source

NanoTag is an improved method to map interactions between DNA and proteins not requiring IgG

Scientific Reports
Genome-wide profiling of DNA–protein interactions in cells can provide important information about mechanisms of gene regulation. Most current methods for genome-wide profiling of DNA-bound proteins such as ChIP-seq and CUT&Tag use conventional IgG ...
Maria A. Dimitriu, Rodrigo G. Arzate-Mejía, Leonard C. Steg, Pierre-Luc Germain, Isabelle M. Mansuy   +4 more
doaj   +1 more source

Advances in Visualizing Cytosine Methylation and Allele‐Specific Epigenetic States in Tissue Context

Pathology International, Volume 76, Issue 6, June 2026.
The ICON method enables sequence‐specific, bisulfite‐free visualization of DNA methylation through chemical recognition of methylated cytosines. Following probe hybridization under mild denaturing conditions, methylation‐dependent interstrand complexes are stabilized by covalent crosslinking.
Sohei Kitazawa, Ryuma Haraguchi, Riko Kitazawa   +2 more
wiley   +1 more source

Molecular Clocks in Translational Roadmap for Circadian‐Based Therapeutics in Lung Diseases

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
High‐amplitude circadian oscillations maintain lung immune and epithelial homeostasis. Chronic inflammation dampens peripheral clock amplitude, driving chronodisruption, barrier dysfunction, and remodeling. Clock‐targeted therapies re‐entrain the lung circadian clock, restore rhythmic immune resolution, and promote functional lung repair.
Kingshuk Panda, Renu Khasa, Srinivasan Chinnapaiyan, Saurabh Aggarwal, Irfan Rahman, Hoshang Unwalla   +5 more
wiley   +1 more source

Functional analysis of the HOX11 target genes ALDH1A1 and FHL1

, 2004
HOX11 is a developmental regulator that plays a crucial role in the normal development of the spleen and is also aberrantly activated by the t(10;14)(q24;q11) and variant t(7;10)(q35;q24) translocations in a subset of T-cell acute lymphoblastic ...
Rice, Kim
core  

Core promoter-specific function of a mutant transcription factor TFIID defective in TATA-box binding

, 1995
In conjunction with other general initiation factors, the TATA box- binding protein (TBP) can direct basal transcription by RNA polymerase II from TATA-containing promoters, but its stable interaction with TBP- associated factors (TAFs) in the TFIID ...
Roeder, Robert G., Oelgeschläger, Thomas, Martinez, Ernest, L'Etoile, Noelle D., Zhou, Qiang, Berk, Arnold J.   +5 more
core   +1 more source

The heat-shock protein Apg-2 binds to the tight junction protein ZO-1 and regulates transcriptional activity of ZONAB

, 2006
The tight junction adaptor protein ZO-1 regulates intracellular signaling and cell proliferation. Its Src homology 3 (SH3) domain is required for the regulation of proliferation and binds to the Y-box transcription factor ZO-1-associated nucleic acid ...
Balda, MS, Matter, K, Tsapara, A
core