Results 111 to 120 of about 49,724 (234)

Characterization of TATA Box Binding Protein Interaction with Minicircle DNA [PDF]

, 2005
Protein-induced bending of DNA plays an important role in regulating its transcription, replication, recombination, and packaging into nucleosomes. In particular, many general and gene-specific transcription factors bend DNA. The TATA box-binding protein
Byun, Jung Shin
core  

Experimental characterization of Cis-acting elements important for translation and transcription in Halophilic Archaea

, 2007
Summary The basal transcription apparatus of archaea is well characterized. However, much less is known about the mechanisms of transcription termination and translation initation.
Jörg Soppa, Oliver Hering, Brenneis, Mariam, Mariam Brenneis, Soppa, Jörg (Prof. Dr.), Brenneis Mariam, Hering, Oliver, Lange, Christian, Christian Lange, Hering Oliver, Soppa Jörg, Lange Christian   +11 more
core   +1 more source

Structure of a rare non-standard sequence k-turn bound by L7Ae protein [PDF]

, 2014
Kt-23 from Thelohania solenopsae is a rare RNA kink turn (k-turn) where an adenine replaces the normal guanine at the 2n position. L7Ae is a member of a strongly conserved family of proteins that bind a range of k-turn structures in the ribosome, box C/D
Huang, Lin, Lilley, David M J; id_orcid
core   +1 more source

Crystal structure of the full Swi2/Snf2 remodeler Mot1 in the resting state

eLife, 2018
Swi2/Snf2 ATPases remodel protein:DNA complexes in all of the fundamental chromosome-associated processes. The single-subunit remodeler Mot1 dissociates TATA box-binding protein (TBP):DNA complexes and provides a simple model for obtaining structural ...
Agata Butryn, Stephan Woike, Savera J Shetty, David T Auble, Karl-Peter Hopfner   +4 more
doaj   +1 more source

Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila

Advanced Science, Volume 13, Issue 31, 4 June 2026.
Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu, Xuedi Zhang, Ying Zhou, Jie Zheng, Angyang Sun, Kailong Zhuang, Weiwei Bao, Guanjun Gao   +7 more
wiley   +1 more source

Development of a System for the Study of Protein−Protein Interactions in Planta:  Characterization of a TATA-Box Binding Protein Complex in Oryza sativa

, 2016
We describe a simple, rapid method for protein complex purification in planta. Using a biotin peptide as an affinity tag with TATA-box binding protein (TBP), 86 unique proteins present in the purified complex were identified by tandem mass spectrometry ...
Paul Budworth (3087807), Jingping Zhong (3087810), Donna Eckert (3087813), Paul A. Haynes (1538398), Nancy L. Andon (1930666), John R. Yates (1234548), Xun Wang (138298), Shiping Zhang (31498), Xinping Yang (32981)   +8 more
core   +1 more source

Sequence specificity of single-stranded DNA-binding proteins:a novel DNA microarray approach [PDF]

, 2007
We have developed a novel DNA microarray-based approach for identification of the sequence-specificity of single-stranded nucleic-acid-binding proteins (SNABPs).
Estibeiro, Peter, Heinemann, U., Wear, M.A., Max, K.E., Morgan, Hugh P, Max, Klaas E A, Sadler, P.J., Morgan, H.P., Walkinshaw, M.D., Heinemann, Udo, Walkinshaw, Malcolm D, Wear, Martin A, Gallagher, Maurice P, Cubeddu, L., Sadler, Peter J, Estibeiro, P., Gallagher, M.P., Cubeddu, Liza   +17 more
core   +1 more source

Indole and synthetic derivative activate chaperone expression to reduce polyQ aggregation in SCA17 neuronal cell and slice culture models

Drug Design, Development and Therapy, 2014
Pin-Jui Kung,1,* Yu-Chen Tao,1,* Ho-Chiang Hsu,1 Wan-Ling Chen,1 Te-Hsien Lin,1 Donala Janreddy,2 Ching-Fa Yao,2 Kuo-Hsuan Chang,3 Jung-Yaw Lin,1 Ming-Tsan Su,1 Chung-Hsin Wu,1 Guey-Jen Lee-Chen,1 Hsiu-Mei Hsieh-Li1 1Department of Life Science ...
Kung PJ, Tao YC, Hsu HC, Chen WL, Lin TH, Janreddy D, Yao CF, Chang KH, Lin JY, Su MT, Wu CH, Lee-Chen GJ, Hsieh-Li HM   +12 more
doaj  

Multiplexed Retinoic Acid Signal Reporters for In Vivo and In Vitro Use

genesis, Volume 64, Issue 3, June 2026.
ABSTRACT Here we describe the optimisation of a modular, generally applicable and rapid method to make multimerised signaling‐molecule reporters for detecting different retinoic acid concentrations. The technical plasmid design allows for the easy exchange of reporters, promoters, signal‐responsive elements as well as for the multimerization of entire ...
Craig Smith, Bianca Black, Ric Broadhurst, Stacey Parbhu, Peter L. Pfeffer   +4 more
wiley   +1 more source

Enhanced Binding of the TATA-Binding Protein to TATA Boxes Containing Flanking Cisplatin 1,2-Cross-Links^†

, 2016
The TATA-binding protein (TBP) is essential for transcription initiation in eukaryotes. TBP recognizes and binds to the minor groove of a consensus sequence, TATAAA, known as the TATA box or TATA element.
Stephen J. Lippard (1233759), Seth M. Cohen (1271355), Elizabeth R. Jamieson (2609185)   +2 more
core   +1 more source