Results 121 to 130 of about 49,724 (234)

TATA-box-binding protein promotes hepatocellular carcinoma metastasis through epithelial-mesenchymal transition. [PDF]

Hepatol Commun, 2023
Cao J, Yang S, Luo T, Yang R, Zhu H, Zhao T, Jiang K, Xu B, Wang Y, Chen F.   +9 more
europepmc   +1 more source

The Role of Neutrophils and NETosis in Diseases: The Implications for Therapy

MedComm, Volume 7, Issue 6, June 2026.
Neutrophils secrete cytokines, express specific surface proteins, increase or decrease in cell count, and their ratio to lymphocyte count can be used as biomarkers to characterize collective status and disease progression. Neutrophils can monitor and track the body's health status, “Wei Bing” status, disease status, and different times of disease ...
Zhen Ma, Qing Wang, Yusheng Zhang, Yang Li, Hongwei Wu, Hongjun Yang, Xianyu Li   +6 more
wiley   +1 more source

TATA-box-binding protein-associated factor 15 is a novel biomarker that promotes cell proliferation and migration in gastrointestinal stromal tumor. [PDF]

World J Gastroenterol, 2023
Guo CM, Tang L, Li X, Huang LY.
europepmc   +1 more source

Pathways of Protein Secretion in Prokaryotes and Eukaryotes: Molecular Mechanisms, Biological Functions, and Therapeutic Opportunities

MedComm, Volume 7, Issue 6, June 2026.
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang, Jingfei Shi, Linlin Xu, Guangrui Zhao, Yue Chen, Lin Cheng, Xiaokang Li, Zhigang Sun, Shuhong Huang   +8 more
wiley   +1 more source

Behavioral disorder, dementia, ataxia, and rigidity in a large family with TATA box-binding protein mutation.

, 2004
BACKGROUND: Spinocerebellar ataxia type 17 is an autosomal dominant cerebellar ataxia caused by a CAG repeat expansion in the TATA box-binding protein gene. Ataxia is typically the first sign whereas behavioral symptoms occur later.
G. Casari, D'ADAMO, ADAMO PIO, J. F. Foncin, S. a. M, F. Maltecca, A. C. Bruni, A. Servadio, R. Maletta, K. H. El, A. Filla, C. Duyckaerts, J. Takahashi Fujigasaki, G. . Michele   +12 more
core   +1 more source

Ocular surface disease in atopic dermatitis

Acta Ophthalmologica, Volume 104, Issue S291, Page S4-S28, June 2026.
ENGLISH SUMMARY Atopic keratoconjunctivitis (AKC) is a severe ocular surface disease (OSD) that significantly affects patients' quality of life and can lead to blindness. AKC is associated with atopic dermatitis (AD), a common chronic inflammatory skin disease affecting both children and adults.
Pernille May Hansen
wiley   +1 more source

Thrombospondin‐4 is upregulated in abdominal aortic aneurysm: A vasoprotective response with potential therapeutic relevance

British Journal of Pharmacology, Volume 183, Issue 12, Page 3321-3339, June 2026.
TSP4 is upregulated in human and experimental AAA. TSP4 knockdown accelerated AAA formation and exacerbated both vascular inflammation and remodelling, emphasizing that TSP4 upregulation may represent a protective response against AAA. Our findings suggest that preserving TSP4 could be a useful strategy in the clinical management of AAA.
Laia Blanco‐Casoliva, Lidia Puertas‐Umbert, Judith Alonso, Rafael Almendra‐Pegueros, Saray Varona, Mercedes Camacho, Gemma Arderiu, Lluís Asmarats, Marta Alegret, Jose Martinez‐Gonzalez, Cristina Rodriguez   +10 more
wiley   +1 more source

A structural investigation of bacterial twin-arginine translocation (tat) complexes by single-particle electron microscopy [PDF]

The Twin arginine translocase (Tat) pathway was first characterised in chloroplast thylakoid membranes in the late 1990s. It has since been identified in the plasma membranes of both Gram-positive and Gram-negative bacteria.
Beck, Daniel K.
core  

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

The FEBS Journal, Volume 293, Issue 12, Page 3502-3527, June 2026.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio, Ana Lucia Cuadros Gamboa, Martina Bertocchi, Filippo Chiesa, Francesca Cargnin, Ettore Mosca, Paride Pelucchi, Viviana Tritto, Stefania Corti, Isabella Ceccherini, Paola Riva, Roberta Benfante, Diego Fornasari   +12 more
wiley   +1 more source

PlantCTCIP: Chromatin Interaction Prediction Using Convolutional Neural Network and Transformer in Plants

Plant Biotechnology Journal, Volume 24, Issue 6, Page 3634-3655, June 2026.
ABSTRACT Chromatin interactions establish spatial proximity between distant regulatory elements and their target genes, significantly influencing gene expression, and phenotypic traits. In this study, we present a plant chromatin interaction prediction model called PlantCTCIP based on Convolutional Neural Networks and Transformer.
Zhenye Wang, Siyu Zhou, Ze Guo, Zilan Ning, Jiaqi Cai, Ran Zhao, Ao Xie, Quan Li, Jiangling Zhang, Yongsheng Zhao, Peizhang Li, Haiping Si, Jianbing Yan, Yong Peng, Jianxiao Liu   +14 more
wiley   +1 more source