Results 141 to 150 of about 45,863 (244)

Methionine Synthase Interacts With the Methionine Adenosyl‐Transferase MATα2 and the DNA Methyltransferase DNMT3b in the Nucleus

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
This study shows that methionine synthase (MS) interacts with MATα2, responsible for SAM production, and the methyltransferase DNMT3b in the nucleus. These results support the idea that spatial compartmentalization of one‐carbon metabolism could play a major role in regulating the epigenome.
Manon Jeandel, Jean‐Marc Alberto, Okan Baspinar, Aurélie Robert, Natacha Dreumont, Zeinab Alsahly, David Meyre, Jean‐Louis Guéant, David Coelho   +8 more
wiley   +1 more source

Glucocorticoid Receptor (GR) and Specificity Protein 1 (Sp1) or Sp3 Transactivate the Bovine Alphaherpesvirus 1 (BoHV-1)-Infected Cell Protein 0 Early Promoter

Viruses
Bovine alphaherpesvirus 1 (BoHV-1) acute infection leads to latently infected sensory neurons in trigeminal ganglia. During lytic infection, the immediate early expression of infected cell protein 0 (bICP0) and bICP4 is regulated by an immediate early ...
Sankha Hewawasam, Fouad S. El-Mayet, Clinton Jones   +2 more
doaj   +1 more source

A schematic model of gene activation mechanism through 8-OHdG modification at methylated CpG locus upstream of TATA-box.

, 2014
When the CpG locus is not methylated, TBP gains access to TATA-box and transactivates the gene. (B) By the addition of single methylation at the CpG locus, the sequence becomes the target of MeCP2.
Yasuhiro Minami (87853), Riko Kitazawa (600865), Michiru Nishida (600868), Yutaka Takahashi (600869), Sohei Kitazawa (147162), Ryuma Haraguchi (134976), Michiko Mori (528838), Takeshi Kondo (600866), Yasuhiro Hamada (600867), Kiyoshi Mori (289003)   +9 more
core   +1 more source

The Lipid Droplet–Associated Hydrolase Is Associated With Obesity and Adipose Tissue Inflammation in Children

Obesity, Volume 34, Issue 7, Page 1420-1432, July 2026.
ABSTRACT Objective The lipid droplet–associated hydrolase (LDAH) is a lipid droplet–associated protein with an uncharacterized role in human adipose tissue (AT) and obesity; we aimed to investigate its role in human AT and its relevance for childhood obesity.
Claudia Vales‐Villamarín, Antje Berthold, Martin Lacher, Antje Körner, Kathrin Landgraf   +4 more
wiley   +1 more source

The association of BBR with DNA can suppress the interaction between TBP and the TATA box.

, 2013
(A) represents the suppressive effect of BBR on gene transcription in a cell-free system, where actinomycin D (AD) was used as the positive control drug because of its well-known transcription inhibitory activity. (B) represents the suppressive effect of
Lijun Du (345610), Yushuang Chai (345607), Fan Lei (288658), Michael M. Kheir (288659), Jun Hu (5721), Yugang Wang (317500), Dongming Xing (345609)   +6 more
core   +1 more source

Genome‐wide analysis of DNA methyltransferases in a model extremophyte, Schrenkiella parvula: Transcriptional dynamics during development and under salt stress

Annals of Applied Biology, Volume 189, Issue 1, July 2026.
Classification of DMTs into 4 subfamilies: two METs, three CMTs, three DRMs, and one DNMT2. The cis‐elements are associated with stress‐response, hormonal regulation, light‐response, and development. RNA‐seq analysis revealed differential expression of DMTs under NaCl stress.
Seher Yolcu, Amin Mirshamsi Kakhki, Ahmad Jalilian, Emre Sevindik, Ismail Turkan   +4 more
wiley   +1 more source

The Transcription Factor OsWRKY64 Interacts With OsART1 to Positively Regulate Al Resistance in Rice

Plant Biotechnology Journal, Volume 24, Issue 7, Page 4656-4671, July 2026.
A proposed working model illustrating the cooperative regulation of Al tolerance by OsWRKY64 and OsART1 in rice. Under Al stress conditions in acidic soil, the transcription factor OsART1 directly binds to the promoter of OsWRKY64 to activate its transcription. The synthesized OsWRKY64 protein then physically interacts with OsART1 in the nucleus.
Changzhao Chen, Qiang Zhang, Yonggang Xu, Jibo Yang, Jing Yan, Mengmeng Jiang, Lu Zheng, Tingwu Liu, Jiu Huang, Renfang Shen, Xiaofang Zhu   +10 more
wiley   +1 more source

TATA box-binding protein-related factor 3 drives the mesendoderm specification of human embryonic stem cells by globally interacting with the TATA box of key mesendodermal genes. [PDF]

Stem Cell Res Ther, 2020
Liang H, Zhang P, Bai HJ, Huang J, Yang HT.   +4 more
europepmc   +1 more source

Unannotated single nucleotide polymorphisms in the TATA box of erythropoiesis genes show in vitro positive involvements in cognitive and mental disorders. [PDF]

BMC Med Genet, 2020
Ponomarenko M, Sharypova E, Drachkova I, Chadaeva I, Arkova O, Podkolodnaya O, Ponomarenko P, Kolchanov N, Savinkova L.   +8 more
europepmc   +1 more source

Analysis of TATA-box binding protein associated factor 4b gene mutations in a Chinese population with nonobstructive azoospermia. [PDF]

Medicine (Baltimore), 2020
Xi Q, Zhang H, Zhang X, Jiang Y, Wang R, Liu R, Zhang H.   +6 more
europepmc   +1 more source