Results 161 to 170 of about 45,863 (244)

Development and Validation of Nomogram Predicting Survival in Resectable Gallbladder Cancer

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, Volume 33, Issue 6, Page 454-462, June 2026.
Patkar and colleagues developed and internally validated a nomogram predicting overall survival after resection of gallbladder cancer using a large cohort of 1045 patients. The model demonstrated good accuracy and discriminative capacity, and stratified patients into prognostically distinct risk groups, supporting more objective selection and ...
Shraddha Patkar   +9 more
wiley   +1 more source

The Role of Neutrophils and NETosis in Diseases: The Implications for Therapy

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Neutrophils secrete cytokines, express specific surface proteins, increase or decrease in cell count, and their ratio to lymphocyte count can be used as biomarkers to characterize collective status and disease progression. Neutrophils can monitor and track the body's health status, “Wei Bing” status, disease status, and different times of disease ...
Zhen Ma   +6 more
wiley   +1 more source

Pathways of Protein Secretion in Prokaryotes and Eukaryotes: Molecular Mechanisms, Biological Functions, and Therapeutic Opportunities

open access: yesMedComm, Volume 7, Issue 6, June 2026.
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang   +8 more
wiley   +1 more source

Establishment of an Agrobacterium‐mediated CRISPR/Cas9 Genome Editing System for Kenaf (Hibiscus cannabinus)

open access: yes
Plant Biotechnology Journal, Volume 24, Issue 7, Page 4719-4721, July 2026.
Xueqing Pan   +10 more
wiley   +1 more source

Ocular surface disease in atopic dermatitis

open access: yesActa Ophthalmologica, Volume 104, Issue S291, Page S4-S28, June 2026.
ENGLISH SUMMARY Atopic keratoconjunctivitis (AKC) is a severe ocular surface disease (OSD) that significantly affects patients' quality of life and can lead to blindness. AKC is associated with atopic dermatitis (AD), a common chronic inflammatory skin disease affecting both children and adults.
Pernille May Hansen
wiley   +1 more source

Thrombospondin‐4 is upregulated in abdominal aortic aneurysm: A vasoprotective response with potential therapeutic relevance

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 12, Page 3321-3339, June 2026.
TSP4 is upregulated in human and experimental AAA. TSP4 knockdown accelerated AAA formation and exacerbated both vascular inflammation and remodelling, emphasizing that TSP4 upregulation may represent a protective response against AAA. Our findings suggest that preserving TSP4 could be a useful strategy in the clinical management of AAA.
Laia Blanco‐Casoliva   +10 more
wiley   +1 more source

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

open access: yesThe FEBS Journal, Volume 293, Issue 12, Page 3502-3527, June 2026.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio   +12 more
wiley   +1 more source

Analysis of the interaction of TATA-box binding protein 1 and 2 from <i>Taenia solium</i> to TATA-box: structural factors related to selectivity and affinity. [PDF]

open access: yesTranscription
Rodríguez-Lima O   +9 more
europepmc   +1 more source

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