The gammaherpesviral TATA-box-binding protein directly interacts with the CTD of host RNA Pol II to direct late gene transcription. [PDF]
Castañeda AF +6 more
europepmc +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
TATA-Box Binding Protein O-GlcNAcylation at T114 Regulates Formation of the B-TFIID Complex and Is Critical for Metabolic Gene Regulation. [PDF]
Hardivillé S +9 more
europepmc +1 more source
In Situ Regenerative Adduct Assisted p‐Type Doping of Organic Semiconductor
An in situ regenerative adduct‐assisted (IRAA) doping strategy is introduced for p‐type doping of organic semiconductors. A regenerating adduct serves as the dopant, enabling highly efficient doping with a choice of counterions. The generality of this approach provides a scalable route to dope a wide range of hole‐transport materials with high thermal ...
Brijesh K. Patel +8 more
wiley +1 more source
Targeted PMP22 TATA-box editing by CRISPR/Cas9 reduces demyelinating neuropathy of Charcot-Marie-Tooth disease type 1A in mice. [PDF]
Lee JS +14 more
europepmc +1 more source
TATA Box Mimicry by TFIID [PDF]
Burley, Stephen K., Roeder, Robert G.
openaire +1 more source
Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila
Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu +7 more
wiley +1 more source
Characterization of TATA Box Binding Protein Interaction with Minicircle DNA [PDF]
Protein-induced bending of DNA plays an important role in regulating its transcription, replication, recombination, and packaging into nucleosomes. In particular, many general and gene-specific transcription factors bend DNA. The TATA box-binding protein
Byun, Jung Shin
core
Multiplexed Retinoic Acid Signal Reporters for In Vivo and In Vitro Use
ABSTRACT Here we describe the optimisation of a modular, generally applicable and rapid method to make multimerised signaling‐molecule reporters for detecting different retinoic acid concentrations. The technical plasmid design allows for the easy exchange of reporters, promoters, signal‐responsive elements as well as for the multimerization of entire ...
Craig Smith +4 more
wiley +1 more source

