Results 1 to 10 of about 22,844 (235)
Hadisteki İlleti Tespit ve Tenkit Prensibi Olarak: 'Filan Râvinin Rivâyetine Benzemiyor' İfadesi
Cumhuriyet İlahiyat Dergisi, 2023 Hadislerin sıhhatinin tespiti için muhaddisler tarafından hadisin sened ve metnini ilgilendiren birtakım şartlar belirlenmiştir. Bu şartların sened ve metne bakan yönleri bulunmaktadır. Bu şartlardan biri de hadisin illetli olmamasıdır. Hadisin sıhhatini
Bahadır Opus
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Biology Open, 2021 Intestinal cell lineage differentiation is a tightly regulated mechanism that involves several intracellular signaling pathways affecting the expression of a variety of transcription factors, which ultimately regulate cell specific gene expression ...
Sepideh Fallah, Jean-François Beaulieu
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Inhibition of TAZ impairs the migration ability of melanoma cells
Open Life Sciences, 2023 Malignant melanoma (MM) is characterized by rapid growth, frequent metastasis, and high mortality. Targeted therapy for MM is still a research hotspot due to the increasing understanding of the hippo pathway.
Zhang Hao +4 more
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Yurak-Samoyeds: Problems of Ethnic Identification
Арктика и Север, 2021 The article is devoted to the poorly studied problem of the origin of the name Yuraki, which the Russians, as well as the Enets and Nganasans, called the group of the Samoed-speaking population that wandered along the northern outskirts of Western ...
Yuriy N. KVASHNIN
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Cancer Biology & Medicine, 2021 Objective: Bone metastasis is a clinically important outcome of prostate carcinoma (PC). We focused on the phenotypic and functional characterization of a particularly aggressive phenotype within the androgen-independent bone metastasis-derived PC3 cell ...
Rosaria A. Fontanella +14 more
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TAZ Forces Lateral Inhibition [PDF]
Developmental Cell, 2019 New mechanisms by which cells communicate to specify cell fate during animal development are continuously being discovered. In a recently published article in Cell, Xia et al. (2019) identify the transcriptional regulator TAZ as a novel mediator of lateral inhibition in zebrafish oogenesis that directs cell fate through mechanical cues.
Joseph G, Kern, Xaralabos, Varelas
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Polish Journal of Pathology, 2022 There is growing evidence which indicates that the development and the biological features of cancer such as the invasion, metastases and recurrence are related to the presence and behavior of the cancer stem cells (CSC).
Olga Stasikowska-Kanicka +4 more
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YAP/TAZ regulates the expression of proteoglycan 4 and tenascin C in superficial-zone chondrocytes [PDF]
European Cells & Materials, 2020 The roles of cell division control protein 42 homologue (CDC42) and actin polymerisation in regulating the phenotype of superficial-zone chondrocytes (SZCs) have been demonstrated in vitro; however, the signalling pathway(s) downstream have yet to be ...
E Delve +5 more
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Cells, 2020 Transcriptional coactivator with a PDZ-binding motif (TAZ) is one of the mammalian orthologs of Drosophila Yorkie, a transcriptional coactivator of the Hippo pathway. TAZ has been suggested to function as a regulator that modulates the expression of cell
Chiharu Miyajima +8 more
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Mechanisms of YAP/TAZ transcriptional control [PDF]
Cell Stress, 2021 Dysregulated gene expression is intrinsic to cell transformation, tumorigenesis and metastasis. Cancer-specific gene-expression profiles stem from gene regulatory networks fueled by genetic and epigenetic defects, and by abnormal signals of the tumor microenvironment.
Battilana G., Zanconato F., Piccolo S.
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