Results 11 to 20 of about 22,844 (235)
Jianpi Jiedu Xiaozheng Fang Regulates Hepatocellular Carcinoma Proliferation and Metastasis Based on Network Pharmacology [PDF]
Journal of Cellular and Molecular Medicine, Volume 30, Issue 5, March 2026.ABSTRACT Hepatocellular carcinoma (HCC) is a primary malignant tumour that impacts patients' quality of life. Currently, clinical experience from The First Affiliated Hospital of Guangzhou University of Chinese Medicine suggests that Jianpi Jiedu Xiaozheng Fang (JPJDXZF) demonstrates promising efficacy in the treatment of HCC.
Bin Li +7 more
wiley +2 more sources
Hippo Pathway Drives Durable Non‐Cell‐Autonomous Ferroptosis Resistance in Lung Cancer [PDF]
Cancer Science, Volume 117, Issue 3, Page 683-694, March 2026.YAP/TAZ, key effectors in lung cancer progression, paradoxically sensitize tumor cells to ferroptosis. This study reveals that YAP/TAZ‐low cells confer non‐cell‐autonomous, GCH1‐mediated durable ferroptosis resistance to neighboring YAP/TAZ‐high cells via a soluble factor, highlighting a Hippo pathway‐linked mechanism of tumor adaptation and survival ...
Mohamed Fathi Saleh +6 more
wiley +2 more sources
Advanced Science, 2021 The Hippo pathway effector TAZ promotes cellular growth, survival, and stemness through regulating gene transcription. Recent studies suggest that TAZ liquid–liquid phase separation (LLPS) compartmentalizes key cofactors to activate transcription ...
Yiju Wei +10 more
doaj +1 more source
The Influence of Gandhi's Economic Thoughts on the Indian Economy
Indialogs: Spanish Journal of India Studies, 2021 Gandhi wanted the Indian economy to center around autonomous village republics rather than work on the back of large-scale industries or consumption expenditure. Gandhi’s principles for formulating his economic thoughts were based on a call to ‘return to
Taz Mazinder Barua
doaj +1 more source
Tafazzin (TAZ) promotes the tumorigenicity of cervical cancer cells and inhibits apoptosis. [PDF]
PLoS ONE, 2017 Tafazzin (TAZ) is often aberrantly expressed in some cancers, including rectal cancer and thyroid neoplasms. However, the function of TAZ in cervical cancer cells remains unknown.
Mei Chen, Yuan Zhang, Peng-Sheng Zheng
doaj +1 more source
Drug Design, Development and Therapy, 2022 Yajing Fu,1 Dan Ma,2 Fengyan Fan,3 Tongke Sun,1 Ruiqi Han,1 Yanran Yang,1 Jun Zhang1 1Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration ...
Fu Y +6 more
doaj
PLoS ONE, 2020 Transcriptional co-activator with PDZ-binding motif (TAZ) plays versatile roles in the regulation of cell proliferation and differentiation. TAZ activity changes in response to the cellular environment such as mechanic and nutritional stimuli, osmolarity,
Manami Kodaka +17 more
doaj +1 more source
Dysfunctional Mechanotransduction through the YAP/TAZ/Hippo Pathway as a Feature of Chronic Disease
Cells, 2020 In order to ascertain their external environment, cells and tissues have the capability to sense and process a variety of stresses, including stretching and compression forces.
Mathias Cobbaut +6 more
doaj +1 more source
TAZ is required for chondrogenesis and skeletal development
Cell Discovery, 2021 Chondrogenesis is a major contributor to skeletal development and maintenance, as well as bone repair. Transcriptional coactivator with PDZ-binding motif (TAZ) is a key regulator of osteogenesis and adipogenesis, but how TAZ regulates chondrogenesis and ...
Yang Li +3 more
doaj +1 more source
YAP and TAZ regulate cell volume [PDF]
Journal of Cell Biology, 2019 How mammalian cells regulate their physical size is currently poorly understood, in part due to the difficulty in accurately quantifying cell volume in a high-throughput manner. Here, using the fluorescence exclusion method, we demonstrate that the mechanosensitive transcriptional regulators YAP (Yes-associated protein) and TAZ (transcriptional ...
Nicolas A. Perez-Gonzalez +20 more
openaire +4 more sources