Results 41 to 50 of about 283,612 (294)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Services to Industry by Libraries of Federal Government Agencies [PDF]

open access: yes, 1966
published or submitted for ...
Gray, Dwight E., Johnson, J. Burlin
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Glossary on renewable energy and landscape quality: the glossary [PDF]

open access: yes, 2018
The energy supply sector is considered a major polluter by the emission of greenhouse gases in the ...
Kruse, Alexandra, Mickovski, Slobodan B.
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Se vogliamo che tutto rimanga com'è, bisogna che tutto deva essere scritto in inglese [PDF]

open access: yes, 2012
The knowledge of foreign professional literature which is not written in English language is rare in the habit of American library science, and it is easily recognizable if we consider the citations of works not written in English.
Bade, David
core  

Can Hamiltonians be boundary observables in Parametrized Field Theories?

open access: yes, 2010
It has been argued that holography in gravitational theories is related to the existence of a particularly useful Gauss Law that allows energy to be measured at the boundary.
Andrade, Tomas   +2 more
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Fiberwise homogeneous fibrations of the 3-dimensional space forms by geodesics

open access: yes, 2015
A fibration of a Riemannian manifold is fiberwise homogeneous if there are isometries of the manifold onto itself, taking any given fiber to any other one, and preserving fibers.
Nuchi, Haggai
core   +1 more source

What Level of Quality can Neural Machine Translation Attain on Literary Text? [PDF]

open access: yes, 2018
Given the rise of a new approach to MT, Neural MT (NMT), and its promising performance on different text types, we assess the translation quality it can attain on what is perceived to be the greatest challenge for MT: literary text.
Toral, Antonio, Way, Andy
core   +3 more sources

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