Results 11 to 20 of about 2,733 (199)

Eczema Monkeypoxicum Following Sexual Transmission Treated With Tecovirimat

JEADV Clinical Practice
Mpox is a zoonotic viral infection caused by monkeypox virus (MPXV) and risk factors for its dissemination include previous dermatoses such as atopic dermatitis [1].
Andrés Vidal González, Sergio López Alcázar, José Ángel Amat Sánchez, Francisco Vergara Barria, Rosa Feltes Ochoa, Elena Sendagorta Cudos, Pedro Herranz Pinto   +6 more
doaj   +2 more sources

Ocular mpox presenting as sclerokeratouveitis: A case report [PDF]

IDCases
Purpose: To describe a case of mpox-associated ocular disease in an HIV-infected patient. Case report: A 50-year-old man presented with severe ocular inflammation including corneal ulceration, scleral involvement and anterior uveitis.
N. Domènech-López, P. Marjalizo, I. Bourleau, A. Casablanca-Piñera, L. Moura, J. Rosinés-Fonoll, J. Torras-Sanvicens   +6 more
doaj   +2 more sources

Assessment of three antiviral compounds against Borealpox virus infection in a mouse model [PDF]

Emerging Microbes and Infections
Borealpox virus (BRPV) is a zoonotic orthopoxvirus which was first documented in Alaska in 2015. Although most human infections are mild, a recent fatal case in an immunocompromised individual highlights the importance of studying this emerging pathogen.
Jérémie Prévost, Nikesh Tailor, Angela Sloan, Kathleen Fulton, Sarah J. Medina, Jonathan Audet, Geoff Soule, David Safronetz   +7 more
doaj   +2 more sources

Tecovirimat-Related Substance: Characterization, Hirshfeld Analysis, Theoretical Study, In Silico Toxicity Assessment [PDF]

Molecules
Crystal structures of 4-(trifluoromethyl)benzene-1-carbohydrazide (1), 4-(trifluoromethyl)-N’-{[4-(trifluoromethyl)phenyl]carbonyl}benzohydrazide (2) and (1R,2S,6R,7S,8S,10R)-4-({[4-(trifluoromethyl)phenyl]carbonyl}amino)-4-azatetracyclo [5.3.2.08,10.02 ...
Fengfeng Wang, Xiaowen Hu, Caiyu Zhang, Lin Luan, Zhengzheng Zhou, Yang Liu   +5 more
doaj   +2 more sources

Concurrent Mpox and HSV-1 Proctitis in a Young Male With AIDS: A Case Report of Treatment Failure [PDF]

Case Reports in Infectious Diseases
Managing the mpox in patients with advanced HIV infection and coinfections poses significant challenges. This report discusses a young male with advanced HIV (CD4 count 28) and severe concurrent mpox and HSV-1 proctitis.
Mikhail Sukhoroslov, Fouad Kaddour-Hocine, Muhammad Hammad Ashraf, Navya Mandalapu, Shivani Bansal, Matthew Peachey   +5 more
doaj   +2 more sources

Clinical features and management of individuals admitted to hospital with monkeypox and associated complications across the UK: a retrospective cohort study. [PDF]

, 2022
BACKGROUND: The scale of the 2022 global mpox (formerly known as monkeypox) outbreak has been unprecedented. In less than 6 months, non-endemic countries have reported more than 67 000 cases of a disease that had previously been rare outside of Africa ...
Ai Payne, B, Banerjee, R, Beard, K, Beynon, W, Bond, H, Bracchi, M, Callaby, H, Cole, J, Crowe, S, Cusack, T-P, Dunning, J, Elliott, IA, Fink, DL, Gkrania-Klotsas, E, Harrison, T, Heskin, J, Hodgson, B, Jacobs, N, Johnson, L, Jones, I, Lester, R, Lewthwaite, P, Lim, EY, Luintel, A, Milligan, I, Mody, N, O'Hara, G, Payne, L, Peters, JR, Quartey, J, Rampling, T, Rathish, B, Rimmer, S, Specialist and High Consequence Infectious Diseases Centres Network for Monkeypox, Sturdy, A, Whittington, A, Woolley, SD   +36 more
core   +13 more sources

Mpox in South Asia: A Narrative Review on Epidemiology, Preparedness, and Preventive Strategies. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Monkeypox (Mpox), due to its growing global concern, was declared a public health emergency of worldwide concern by the World Health Organization in August 2024. The monkeypox virus (MPXV), once limited to African regions, has now spread to South Asia, including Pakistan, India, Nepal, and Sri Lanka, and there have been ...
Mawa J, Rimun SN, Rahman NZ, Bhuiyan MA, Shahriar M, Anjum R.   +5 more
europepmc   +2 more sources

Pharmacokinetics of tecovirimat in subjects with Mpox

International Journal of Antimicrobial Agents
To investigate the pharmacokinetics (PK) of tecovirimat in subjects with Mpox.This monocentric, prospective, observational study enrolled subjects with Mpox who received standard treatment with oral tecovirimat. Plasma samples for PK assessment were collected at steady state (5-8 days after initiation of antiviral therapy), before and 3, 5, 7 and 12 h ...
Antonio D'Avolio, Valentina Mazzotta, Amedeo De Nicolò   +2 more
exaly   +3 more sources

Overcoming barriers, driving progress: Clinical science at IAS 2025. [PDF]

J Int AIDS Soc
Abstract Introduction The 13th IAS Conference on HIV Science, held in Kigali, Rwanda (13–17 July 2025), highlighted key advances in clinical research. Presentations focused on sustaining HIV treatment and prevention amid financial constraints, innovations in long‐acting oral antiretrovirals, and the management of comorbidities and co‐infections ...
Cordova E, Sokhela S, Alagaratnam J, Ambrosioni J.   +3 more
europepmc   +2 more sources

Monkeypox Virus: Epidemiology, Virology, Diagnosis, Vaccine, and Therapeutics. [PDF]

MedComm (2020)
This review provides a comprehensive overview of the latest research advances in MPXV, with a focused analysis across five core dimensions: epidemiology, virology, diagnosis, vaccine, and therapeutics. The primary objective of this review is to advance the understanding of MPXV and facilitate the development of more effective diagnostic methods ...
Yan Y, Sun Y, Sun G, Niu C, Zhao X, Zhao M, Liu T, Zhang S, Zhai H, Liu A, Yu S, Pan S, Zhong W, Zhang Y, Li S.   +14 more
europepmc   +2 more sources