Results 41 to 50 of about 1,939 (155)

Pharmacological treatment and vaccines in monkeypox virus: a narrative review and bibliometric analysis

open access: yesFrontiers in Pharmacology, 2023
Mpox (earlier known as monkeypox) virus infection is a recognized public health emergency. There has been little research on the treatment options. This article reviews the specific drugs used to treat mpox virus infection and the vaccines used here ...
Muhammad Aaqib Shamim   +21 more
doaj   +1 more source

Computational Purposing Phytochemicals against Cysteine Protease of Monkeypox Virus: An In-silico Approach

open access: yesJournal of Pure and Applied Microbiology, 2022
The development and evolution of viruses that cause disease have presented a formidable challenge to contemporary medicine and the global economy, not to mention a catastrophic risk to human health.
Poonam Bansal   +8 more
doaj   +1 more source

Monkeypox: a global health emergency

open access: yesFrontiers in Microbiology, 2023
Over the past 2 years, the world has faced the impactful Coronavirus Disease-2019 (COVID-19) pandemic, with a visible shift in economy, medicine, and beyond.
Ruxandra Ilinca Stilpeanu   +9 more
doaj   +1 more source

Antivirals against Monkeypox (Mpox) in Humans: An Updated Narrative Review

open access: yesLife, 2023
As of 29 August 2023, a total of 89,596 confirmed cases of Mpox (monkeypox) have been documented across 114 countries worldwide, with 157 reported fatalities.
Giuseppe Bruno   +1 more
doaj   +1 more source

Acute respiratory distress syndrome due to monkeypox virus

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2023
We report the first case of monkeypox virus (MPXV) associated acute respiratory distress syndrome (ARDS). A 34-year-old French woman with no medical history was admitted to the intensive care unit (ICU) for fever, altered mental status, hypotension and ...
Tona Tchoubou   +6 more
doaj   +1 more source

Tecovirimat for the treatment of severe Mpox in Germany

open access: yesInfection, 2023
Abstract Background In May 2022, a multi-national mpox outbreak was reported in several non-endemic countries. The only licensed treatment for mpox in the European Union is the orally available small molecule tecovirimat, which in Orthopox viruses inhibits the function of a major envelope protein required for the ...
Hermanussen, Lennart   +16 more
openaire   +3 more sources

VP37 Protein Inhibitors for Mpox Treatment: Highlights on Recent Advances, Patent Literature, and Future Directions

open access: yesBiomedicines, 2023
Monkeypox disease (Mpox) has threatened humankind worldwide since mid-2022. The Mpox virus (MpoxV) is an example of Orthopoxviruses (OPVs), which share similar genomic structures. A few treatments and vaccines are available for Mpox.
Shuaibu A. Hudu   +3 more
doaj   +1 more source

Virtual Screening of Bacteriocins From Lactic Acid Bacteria Against Monkeypox DNA Polymerase: Sakacin P and Mundticin KS Emerge as Promising Candidates

open access: yesFood Science &Nutrition, Volume 14, Issue 8, August 2026.
This study employs an in silico virtual screening workflow to evaluate lactic acid bacteria (LAB)‐derived bacteriocins as potential inhibitors of the monkeypox virus DNA polymerase (MPDP). Protein‐peptide docking simulations using the HADDOCK platform revealed that Sakacin P and Mundticin KS possess the highest binding affinities for the MPDP target ...
Melisa Z. Karaman   +6 more
wiley   +1 more source

Comprehensive update on the monkeypox outbreak

open access: yesFrontiers in Microbiology, 2022
Monkeypox (MPX) was first reported in 1970 in humans and outbreaks were restricted and highly localised to endemic regions of western and central Africa.
Asad Mustafa Karim   +7 more
doaj   +1 more source

The Role of Pharmacists in Tackling Mpox: Challenges and Future Prospects: A Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Pharmacists play a key role in managing and mitigating mpox through clinical care, pharmacovigilance, vaccine management, and resilient supply chains. Management focuses on supportive care, infection prevention, and accurate diagnosis, with pharmacists ensuring the availability and rational use of vaccines, disinfectants ...
Ayalew Sirbemo Degebo   +4 more
wiley   +1 more source

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