Results 51 to 60 of about 1,939 (155)

Clinical features and management of human monkeypox [PDF]

Scripta Medica, 2023
The COVID-19 pandemic is abating, but the threat of a new epidemic is growing due to the spread of monkeypox in non-endemic regions of the world. In 2022, there were the monkeypox outbreaks throughout Europe, in the Western Hemisphere. With the cessation
Moisova Diana L., Daguf Vladislav A., Grebennikova Maria A., Tretyakova Yuliya A., Oflidi Georgy K., Filonov Anton R.   +5 more
doaj  

Lyophilized Synthetic Platelets: In Vitro Characterization and In Vivo Evaluation in Mouse Thrombocytopenia Model

Advanced Science, Volume 13, Issue 38, 9 July 2026.
ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon, Dante Disharoon, Shrijal S. Desai, Baylee Traylor, Emily Gahagan, Emma Quill, Kristin Aldridge, Norman F. Luc, Sonali Rohiwal, Shruti Raghunathan, Rebecca Ahn, Sana Syed, Alexander Dornback, Bipin Chakravarthy Paruchuri, Andrew Ditto, Susan M. Shea, Philip C. Spinella, Matthew D. Neal, Michael A. Bruckman, Christa L. Pawlowski, Anirban Sen Gupta   +20 more
wiley   +1 more source

Discovery and Structural Characterization of a Highly Protective Neutralizing Antibody Targeting the Mpox Virus A35R Protein

MedComm, Volume 7, Issue 7, July 2026.
High‐affinity monoclonal antibodies (mAbs) targeting the MPXV EEV protein A35R were rapidly isolated using mRNA‐LNP vaccination and the Beacon single‐cell sorting Optofluidic platform, followed by functional profiling. One mAb, 17H1, potently neutralized authentic MPXV and conferred complete protection in vivo.
Shimeng Bai, Shuo Song, Xin Wang, Yuxin Xiao, Yun Long, Fenfang Wu, Fuxiang Wang, Zhongyi Fan, Jianqing Xu, Maozhou He, Hongzhou Lu   +10 more
wiley   +1 more source

Monkeypox and Pregnancy: Protecting Two Lives

Journal of the Pakistan Medical Association
Dear Madam, Monkeypox virus (MPXV), an emerging zoonotic disease, is becoming a global threat, with an unrelenting surge of cases all over Europe and America, prompting WHO to declare it an international concern on July 23rd, 2023 (1).
Maryum Imran, Javeria Kamran
doaj   +1 more source

Organoids: From Bench to Bedside Applications

MedComm, Volume 7, Issue 6, June 2026.
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li, Rui Cao, Maochen Li, Zichao Tian, Huahao Fan, Bixia Hong, Xiaojuan Liu   +6 more
wiley   +1 more source

Navigating the human-monkeypox virus interactome: HuPoxNET atlas reveals functional insights

Frontiers in Microbiology
Monkeypox virus, a close relative of variola virus, has significantly increased the incidence of monkeypox disease in humans, with several clinical symptoms.
Raghav Kataria, Raghav Kataria, Naveen Duhan, Naveen Duhan, Rakesh Kaundal, Rakesh Kaundal, Rakesh Kaundal   +6 more
doaj   +1 more source

Salsoline derivatives, genistein, semisynthetic derivative of kojic acid, and naringenin as inhibitors of A42R profilin-like protein of monkeypox virus: in silico studies

Frontiers in Chemistry
Monkeypox virus (MPV) infection has developed into a re-emerging disease, and despite the potential of tecovirimat and cidofovir drugs, there is currently no conclusive treatment.
Mohamed Chebaibi, Mohammed Bourhia, Fatima ez-zahra Amrati, Meryem Slighoua, Ibrahim Mssillou, Mourad A. M. Aboul-Soud, Asaad Khalid, Rym Hassani, Dalila Bousta, Sanae Achour, Rachid Benhida, Rachid Daoud   +11 more
doaj   +1 more source

Deciphering Drug Repurposing Strategies: Antiviral Properties of Candidate Agents Against the Mpox Virus

Scientia Pharmaceutica
Monkeypox (Mpox) has re-emerged as a global public health threat, with recent outbreaks linked to novel mutations that enhance viral transmissibility and immune evasion.
Aganze Gloire-Aimé Mushebenge, David Ditaba Mphuthi   +1 more
doaj   +1 more source

Severe Scrotal Cellulitis in a Young Man

JEADV Clinical Practice, EarlyView.
Hamad El Hajj, Vera Al Baaklini, Dima Jeha, Alfred Ammoury   +3 more
wiley   +1 more source

Mpox (Monkeypox) in Pregnancy Updates

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Mpox is a zoonotic viral disease caused by the monkeypox virus, with potential for significant morbidity across all population groups, including pregnant individuals and neonates. Pregnancy represents an immunologically vulnerable state, rendering affected mothers more susceptible to severe disease progression.
Yeshey Dorjey, Deep Kiran Chhetri
wiley   +1 more source