Results 71 to 80 of about 2,733 (199)

Salsoline derivatives, genistein, semisynthetic derivative of kojic acid, and naringenin as inhibitors of A42R profilin-like protein of monkeypox virus: in silico studies

Frontiers in Chemistry
Monkeypox virus (MPV) infection has developed into a re-emerging disease, and despite the potential of tecovirimat and cidofovir drugs, there is currently no conclusive treatment.
Mohamed Chebaibi, Mohammed Bourhia, Fatima ez-zahra Amrati, Meryem Slighoua, Ibrahim Mssillou, Mourad A. M. Aboul-Soud, Asaad Khalid, Rym Hassani, Dalila Bousta, Sanae Achour, Rachid Benhida, Rachid Daoud   +11 more
doaj   +1 more source

Severe Scrotal Cellulitis in a Young Man

JEADV Clinical Practice, EarlyView.
Hamad El Hajj, Vera Al Baaklini, Dima Jeha, Alfred Ammoury   +3 more
wiley   +1 more source

Research Review on Inhibitors of Lumpy Skin Disease Virus: From Biological Characteristics, Drug Repurposing, to Computer‐Aided Drug Design

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
This review summarizes the research progress on inhibitors of lumpy skin disease virus (LSDV), focusing on its biological characteristics and key proteins involved in the viral replication cycle. It compiles various inhibitors (direct‐acting poxvirus inhibitors and host‐directed poxvirus inhibitors) against poxviruses, their mechanisms of action, and ...
Leilei ZHAO, Jing QU, Miao AN, Yang LIU, Xiubo LI, Yiming LIU, Chen PENG, Todd R. Callaway   +7 more
wiley   +1 more source

Deciphering Drug Repurposing Strategies: Antiviral Properties of Candidate Agents Against the Mpox Virus

Scientia Pharmaceutica
Monkeypox (Mpox) has re-emerged as a global public health threat, with recent outbreaks linked to novel mutations that enhance viral transmissibility and immune evasion.
Aganze Gloire-Aimé Mushebenge, David Ditaba Mphuthi   +1 more
doaj   +1 more source

Operationalizing a Hub‐and‐Spoke Telemedicine Model for Mpox Surveillance in a High‐Alert, Zero‐Prevalence Setting: An Observational Study, Real‐World Experience From Iran

Interdisciplinary Perspectives on Infectious Diseases, Volume 2026, Issue 1, 2026.
Background The global monkeypox (Mpox) outbreak prompted heightened surveillance in regions with significant travel links. Fars Province, Iran, implemented a structured telemedicine response to manage patients presenting with Mpox‐like symptoms. Objectives This study aimed to describe and evaluate the impact of a tiered, hub‐and‐spoke telemedicine ...
Owrang Eilami, Nader Eilami, Alireza Heiran, Mehdi Nejat, Mehrab Sayadi, Suraiya Saleem   +5 more
wiley   +1 more source

Monkey Pox – What a Transplant Physician Should Know

Indian Journal of Transplantation
Mpox has gained global attention over the past 2 years, with the World Health Organization declaring it a public health emergency of international concern in August 2024.
Shivam Narendrakumar Shah, Himanshu Patel, Vivek Kute, Subho Banerjee, Ved Prakash Singh, Vishal Parmar, Sonam Dhingra   +6 more
doaj   +1 more source

State‐of‐the‐Art on Model‐Informed Drug Development Approaches for Pediatric Rare Diseases

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 11, Page 1743-1759, November 2025.
ABSTRACT Pediatric rare diseases present unique challenges for drug development due to small patient populations, ethical constraints on clinical trial design, and limited prospectively defined natural history data. Model‐Informed Drug Development (MIDD) has emerged as a powerful paradigm to address these challenges by leveraging quantitative methods ...
Rajesh Krishna, Amitava Mitra, Matthew L. Zierhut, Lilly East, Chandra Durairaj   +4 more
wiley   +1 more source

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, Volume 58, Issue 11, November 2025.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source

Engineered Nile Red Derivatives‐Mediated Efficient Phototherapy Against Drug‐Resistant Bacteria and Monkeypox Virus

Aggregate, Volume 6, Issue 10, October 2025.
TPAOMCN exhibits optimal reactive oxygen species (ROS) generation and photothermal conversion properties. TPAOMCN nanofibers (NFs)‐mediated photodynamic (PDT) and photothermal therapy (PTT) achieved efficient eradication against multidrug‐resistant bacteria and viruses, alleviating inflammation response, promoting wound healing, and providing a ...
Laiping Fang, Wei Wang, Jianan Dai, Yike Tu, Shufang Li, Kuo He, Siya Tong, Yuhui Liao, Ping'an Ma, Guihua Jiang   +9 more
wiley   +1 more source

The Role of Public Health Interventions and Control Measures During Mpox Outbreaks: Enhancing Strategies for Disease Prevention and Management

Public Health Challenges, Volume 4, Issue 3, September 2025.
This paper highlights key public health interventions and control strategies implemented during mpox outbreaks, emphasizing early detection, targeted prevention, and the role of vaccination and education in mitigating disease transmission. ABSTRACT Mpox (formerly—monkeypox) is the second viral pit break after COVID‐19.
Muhammad Shaheer Bin Faheem, Ahmed Ali Khan, Qasra Faheem, Hafiza Qurat Ul Ain, Wajiha Imam, Yusra Aimen, Raheel Ahmed   +6 more
wiley   +1 more source