Results 61 to 70 of about 1,939 (155)
Monkey Pox – What a Transplant Physician Should Know
Mpox has gained global attention over the past 2 years, with the World Health Organization declaring it a public health emergency of international concern in August 2024.
Shivam Narendrakumar Shah +6 more
doaj +1 more source
ABSTRACT Monkeypox is a reemerging zoonotic disease that has been spreading worldwide. Different approaches are being conducted to find effective treatments for this disease. To accelerate therapeutic discovery, we propose telomere‐binding protein (TBP) as a potential drug target because of its important role during virus maturation.
Edinson Gervacio‐Villarreal +12 more
wiley +1 more source
ABSTRACT Chemical, biological, radiological, and nuclear (CBRN) incidents present escalating challenges, particularly in geopolitically unstable regions such as the Middle East and North Africa. Despite advances, gaps exist regarding optimal decontamination protocols and agent‐specific antidote selection algorithms, exacerbated by variable operational ...
Hassan Farhat +6 more
wiley +1 more source
Wei et al. report that MPXV infection induces aerobic glycolysis, a process mediated by the viral protein I3 through lysine crotonylation at its K102 residue. The acetyltransferase MYST1 catalyzes the crotonylation of I3 to inhibit the ubiquitin‐mediated degradation of WDR26.
Pengjun Wei +12 more
wiley +1 more source
Antiviral Drugs for Treatment of Human Monkeypox: A Systematic Review/Meta-analysis
Background. On 23 July 2022, the World Health Organization declared a Public Health Emergency of International Concern. Monkeypox is a zoonotic viral disease caused by the monkeypox virus that is transmitted from animals to humans or from human to human.
Ahmed Mohamed Abdelghany +2 more
doaj +1 more source
Major revision version 13.0 of the European AIDS Clinical Society guidelines 2025
Abstract Background The European AIDS Clinical Society (EACS) guidelines were revised for the 21st time in 2025, with updates covering all aspects of HIV care. Key Points of the Guidelines Update The structure of the guidelines has been reorganized into two parts: Part I focuses on the management and prevention of HIV and related infections, and Part ...
Juan Ambrosioni +19 more
wiley +1 more source
Tecovirimat in the management of poxviruses: a narrative review of available evidence
Introduction Tecovirimat (TPOXX) is an effective antiviral medication recommended for treating smallpox and other Orthopoxvirus infections. With the rise in monkeypox (mpox) cases globally, there is an urgent need to explore therapeutic options to manage
Olalekan John Okesanya +13 more
doaj +1 more source
Identifying potential monkeypox virus inhibitors: an in silico study targeting the A42R protein
Monkeypox (now Mpox), a zoonotic disease caused by the monkeypox virus (MPXV) is an emerging threat to global health. In the time span of only six months, from May to October 2022, the number of MPXV cases breached 80,000 and many of the outbreaks ...
Carolyn N. Ashley +13 more
doaj +1 more source

