Results 61 to 70 of about 2,733 (199)

Monkeypox in humans: a new outbrea [PDF]

, 2022
La infección causada por el Virus de la Viruela del Mono o Monkeypox (MPVX) tiene como reservorio natural los pequeños roedores y tanto el mono como el hombre son huéspedes ocasionales. El agente causal es un Orthopoxvirus (MPVX) que fue aislado en
Alcamí, Antonio, Bouza, Emilio, Burillo, Almudena, Cantón, Rafael, Catalán, Pilar, Cobo, Alejandro, De Lucas Ramos, Pilar, García Botella, Alejandra, García Lledó, Alberto, González del Castillo, Juan, Gómez Pavón, Francisco Javier, Hernández Sampelayo, Teresa, Martín Delgado, Mari Cruz, Martín Sánchez, Francisco Javier, Martínez Sellés, Manuel, Molero García, José María, Moreno Guillén, Santiago, Muñoz, Patricia, Rodríguez Artalejo, Fernando, Ruiz Galiana, Julián, Valerio, Maricela   +20 more
core  

Ensemble Docking of FDA‐Approved and Peruvian Phytochemicals Against Monkeypox Virus Telomere‐Binding Protein

ChemistrySelect, Volume 11, Issue 9, 5 March 2026.
ABSTRACT Monkeypox is a reemerging zoonotic disease that has been spreading worldwide. Different approaches are being conducted to find effective treatments for this disease. To accelerate therapeutic discovery, we propose telomere‐binding protein (TBP) as a potential drug target because of its important role during virus maturation.
Edinson Gervacio‐Villarreal, Georcki Ropón‐Palacios, Claudina Sancho, Jhon Pérez‐Silva, Kewin Otazu, Gustavo E. Olivos‐Ramirez, Karolyn Vega‐Chozo, Yaritza L. Ramirez‐Díaz, Manuel E. Chenet‐Zuta, Ivonne Navarro del Aguila, Mario De la Cruz Flores, Cinthia Aguiar, Ihosvany Camps   +12 more
wiley   +1 more source

Monkeypox and Pregnancy: Protecting Two Lives

Journal of the Pakistan Medical Association
Dear Madam, Monkeypox virus (MPXV), an emerging zoonotic disease, is becoming a global threat, with an unrelenting surge of cases all over Europe and America, prompting WHO to declare it an international concern on July 23rd, 2023 (1).
Maryum Imran, Javeria Kamran
doaj   +1 more source

Blocking Lysine Crotonylation and Aerobic Glycolysis as Targeting Strategy Against mpox Virus Replication

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Wei et al. report that MPXV infection induces aerobic glycolysis, a process mediated by the viral protein I3 through lysine crotonylation at its K102 residue. The acetyltransferase MYST1 catalyzes the crotonylation of I3 to inhibit the ubiquitin‐mediated degradation of WDR26.
Pengjun Wei, Zongzheng Zhao, Ruoqi Xu, Qin Yan, Liangzi Jiang, Fuxiao Geng, Yang Gu, Tianjiao Wang, Jing Zhou, Xiao Li, Qin Yan, Chun Lu, Wan Li   +12 more
wiley   +1 more source

Clinical features and management of human monkeypox [PDF]

Scripta Medica, 2023
The COVID-19 pandemic is abating, but the threat of a new epidemic is growing due to the spread of monkeypox in non-endemic regions of the world. In 2022, there were the monkeypox outbreaks throughout Europe, in the Western Hemisphere. With the cessation
Moisova Diana L., Daguf Vladislav A., Grebennikova Maria A., Tretyakova Yuliya A., Oflidi Georgy K., Filonov Anton R.   +5 more
doaj  

Comparison of the binding energies of approved mpox drugs and phytochemicals through molecular docking, molecular dynamics simulation, and ADMET studies: An in silico approach

Journal of Biosafety and Biosecurity, 2023
The mpox (previously monkeypox) outbreak in more than 100 non-endemic countries in 2022 posed a serious global health concern. Mpox is emerging as a global public health threat from a seemingly neglected disease.
Ranjan K. Mohapatra, Ahmed Mahal, Azaj Ansari, Manjeet Kumar, Jyoti Prakash Guru, Ashish K. Sarangi, Aly Abdou, Snehasish Mishra, Mohammed Aljeldah, Bashayer M. AlShehail, Mohammed Alissa, Mohammed Garout, Ahmed Alsayyah, Ahmad A. Alshehri, Ahmed Saif, Abdulaziz Alqahtani, Fahd A. Alshehri, Aref A. Alamri, Ali A. Rabaan   +18 more
doaj   +1 more source

Navigating the human-monkeypox virus interactome: HuPoxNET atlas reveals functional insights

Frontiers in Microbiology
Monkeypox virus, a close relative of variola virus, has significantly increased the incidence of monkeypox disease in humans, with several clinical symptoms.
Raghav Kataria, Raghav Kataria, Naveen Duhan, Naveen Duhan, Rakesh Kaundal, Rakesh Kaundal, Rakesh Kaundal   +6 more
doaj   +1 more source

Tecovirimat as a Potential Bioavailable inhibitor against MPXVgp158 Established through Molecular Dynamic Simulations and Docking Studies

Journal of Pure and Applied Microbiology, 2022
Monkeypox is a zoonotic viral infection caused by monkeypox virus which belongs to the Poxviridae family of genus Orthopoxvirus. Usually, the virus transmission happens when the individual comes in contact with the infected person through body fluids ...
Varruchi Sharma, Anil Panwar, Vivek Kumar Garg, Hardeep Singh Tuli, Sonal Datta, Anil K Sharma, Abhijit Dey, Deepak Chandran, Kuldeep Dhama   +8 more
doaj   +1 more source

Monkeypox Proctitis: A Case of Targeted Treatment With Tecovirimat

Cureus, 2023
Monkeypox (MPX) is an exanthematous disease first identified in the 1950s, associated with animals in Central and Western Africa, and has since been found sporadically worldwide. In May 2022, a returning family from Nigeria tested positive for MPX, which marked the onset of the current outbreak.
Patel, Premalkumar, Espinosa, Cynthia, Konyala, Varsha, Camps, Nicholas S, Cecilio, Estafenia, Jain, Aakangsha, Tuda, Claudio   +6 more
openaire   +3 more sources

Major revision version 13.0 of the European AIDS Clinical Society guidelines 2025

HIV Medicine, Volume 27, Issue 1, Page 18-32, January 2026.
Abstract Background The European AIDS Clinical Society (EACS) guidelines were revised for the 21st time in 2025, with updates covering all aspects of HIV care. Key Points of the Guidelines Update The structure of the guidelines has been reorganized into two parts: Part I focuses on the management and prevention of HIV and related infections, and Part ...
Juan Ambrosioni, Laura I. Levi, Jasmini Alagaratnam, Abiu Sempere, Andrea Mastrangelo, Paolo Paioni, Cristina Mussini, Catia Marzolini, Susanne Dam Nielsen, Charles Béguelin, Steven Welch, Anna Koval, Luis Mendao, Alasdair Bamford, Alexandra Calmy, Giovanni Guaraldi, Cristiana Oprea, Esteban Martínez, Jürgen K. Rockstroh, The EACS Governing Board   +19 more
wiley   +1 more source