Results 61 to 70 of about 2,019 (146)
Severe Scrotal Cellulitis in a Young Man
JEADV Clinical Practice, EarlyView.
Hamad El Hajj +3 more
wiley +1 more source
Organoids: From Bench to Bedside Applications
MedComm, Volume 7, Issue 6, June 2026.Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li +6 more
wiley +1 more source
Repurposed Medicines for Viruses With Epidemic or Pandemic Potential: A Horizon Scan
Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.ABSTRACT Viruses such as Ebola, Marburg, influenza, mpox, MERS‐CoV, SARS‐CoV, and SARS‐CoV‐2 may be considered pathogens of epidemic or pandemic concern. Developing novel antiviral medicines can be time‐consuming and resource intensive. Repurposing existing medicines with known or potential antiviral activity offers a faster, cost‐effective strategy to
Sola Akinbolade +5 more
wiley +1 more source
Clinical features and management of human monkeypox [PDF]
Scripta Medica, 2023 The COVID-19 pandemic is abating, but the threat of a new epidemic is growing due to the spread of monkeypox in non-endemic regions of the world. In 2022, there were the monkeypox outbreaks throughout Europe, in the Western Hemisphere. With the cessation
Moisova Diana L. +5 more
doaj
Mpox (Monkeypox) in Pregnancy Updates
Health Science Reports, Volume 9, Issue 3, March 2026.ABSTRACT Background Mpox is a zoonotic viral disease caused by the monkeypox virus, with potential for significant morbidity across all population groups, including pregnant individuals and neonates. Pregnancy represents an immunologically vulnerable state, rendering affected mothers more susceptible to severe disease progression.
Yeshey Dorjey, Deep Kiran Chhetri
wiley +1 more source
Antiviral Drugs for Treatment of Human Monkeypox: A Systematic Review/Meta-analysis
Microbes, Infection and ChemotherapyBackground. On 23 July 2022, the World Health Organization declared a Public Health Emergency of International Concern. Monkeypox is a zoonotic viral disease caused by the monkeypox virus that is transmitted from animals to humans or from human to human.
Ahmed Mohamed Abdelghany +2 more
doaj +1 more source
Tecovirimat in the management of poxviruses: a narrative review of available evidence
The Egyptian Journal of Internal MedicineIntroduction Tecovirimat (TPOXX) is an effective antiviral medication recommended for treating smallpox and other Orthopoxvirus infections. With the rise in monkeypox (mpox) cases globally, there is an urgent need to explore therapeutic options to manage
Olalekan John Okesanya +13 more
doaj +1 more source
Pharmacokinetics of tecovirimat in subjects with Mpox
International Journal of Antimicrobial AgentsTo investigate the pharmacokinetics (PK) of tecovirimat in subjects with Mpox.This monocentric, prospective, observational study enrolled subjects with Mpox who received standard treatment with oral tecovirimat. Plasma samples for PK assessment were collected at steady state (5-8 days after initiation of antiviral therapy), before and 3, 5, 7 and 12 h ...
Massimo Tempestilli +16 more
openaire +2 more sources
Drug Repurposing for Monkeypox: An Alternative Strategy for Emergency Response
JPSCR: Journal of Pharmaceutical Science and Clinical ResearchThe global monkeypox (MPOX) outbreak, which has resulted in more than 100,000 confirmed cases across over 120 countries, underscores the urgent need for effective therapeutic strategies. MPOX, caused by a virus belonging to the Orthopoxvirus genus, poses
Luthfi Harbulcholizi +4 more
doaj +1 more source