Results 61 to 70 of about 1,717 (156)

In Vitro Activity of Tedizolid, Dalbavancin, and Ceftobiprole Against Clostridium difficile

Frontiers in Microbiology, 2018
Background:Clostridium difficile (C. difficile) is a major nosocomial pathogen that colonizes in the human gut. Recently, the U.S. FDA approved three new antimicrobial agents against gram-positive bacteria: Tedizolid, Dalbavancin, and Ceftobiprole.
Dana Binyamin, Dana Binyamin, Orna Nitzan, Orna Nitzan, Maya Azrad, Zohar Hamo, Zohar Hamo, Omry Koren, Avi Peretz, Avi Peretz   +9 more
doaj   +1 more source

Tedizolid-Rifampicin Combination Prevents Rifampicin-Resistance on in vitro Model of Staphylococcus aureus Mature Biofilm

Frontiers in Microbiology, 2020
Staphylococcus aureus infections associated with implanted medical devices are difficult to treat and require long-lasting antibiotic therapies, especially when device removal is not possible or easy such as in the case of joint prostheses.
Anna Gidari, Samuele Sabbatini, Elisabetta Schiaroli, Stefano Perito, Daniela Francisci, Franco Baldelli, Claudia Monari   +6 more
doaj   +1 more source

Genetic Characterization of a Linezolid‐ and Penicillin‐Resistant Enterococcus hirae Isolate Co‐Harboring poxtA and pbp5fm

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Linezolid and penicillin are critical for treating multidrug resistant (MDR) Gram‐positive infections, but the emergence of resistance to both seriously threatens public health. Here, we first report the cocarrying poxtA (oxazolidinone resistance) and pbp5fm (β‐lactam resistance) genes by the plasmid in a strain of Enterococcus hirae HDC14‐2 derived ...
Jinhu Huang, Aijuan Li, Mengli Wang, Shushu Gu, He Hu, Xiaoming Wang, Liping Wang, Zhong Peng   +7 more
wiley   +1 more source

Dynamic distribution of systemically administered antibiotics in orthopeadically relevant target tissues and settings

APMIS, Volume 132, Issue 12, Page 992-1025, December 2024.
This review aimed to summarize the current literature on antibiotic distribution in orthopedically relevant tissues and settings where dynamic sampling methods have been used. PubMed and Embase databases were systematically searched. English‐published studies between 2004 and 2024 involving systemic antibiotic administration in orthopedically relevant ...
Maria Bech Damsgaard Nielsen, Andrea René Jørgensen, Maiken Stilling, Mads Kristian Duborg Mikkelsen, Nis Pedersen Jørgensen, Mats Bue   +5 more
wiley   +1 more source

Efficacy and safety of vancomycin compared with those of alternative treatments for methicillin‐resistant Staphylococcus aureus infections: An umbrella review

Journal of Evidence-Based Medicine, Volume 17, Issue 4, Page 729-739, December 2024.
Abstract Objective To summarize the evidence on the efficacy and safety of vancomycin compared with those of alternative treatments in adult patients with methicillin‐resistant Staphylococcus aureus (MRSA) infection. Methods PubMed, Embase, and Web of Science were searched up to December 15, 2023, for systematic reviews and meta‐analyses comparing ...
Sujata Purja, Minji Kim, Yomna Elghanam, Hae Jung Shim, Eunyoung Kim   +4 more
wiley   +1 more source

Potential role of tedizolid phosphate in the treatment of acute bacterial skin infections

Drug Design, Development and Therapy, 2013
Olatz Urbina,1 Olivia Ferrández,1 Mercè Espona,1 Esther Salas,1 Irene Ferrández,2 Santiago Grau1 1Services of Hospital Pharmacy, Hospital Universitari del Mar, Universitat Autònoma de Barcelona, 2Ciència i Tecnologia ...
Urbina O, Ferrández O, Espona M, Salas E, Ferrández I, Grau S   +5 more
doaj  

Differences in oxazolidinone resistance mechanisms and small colony variants emergence of Staphylococcus aureus induced in an in vitro resistance development model

Emerging Microbes and Infections
Invasive Staphylococcus aureus infections are associated with a high burden of disease, case fatality rate and healthcare costs. Oxazolidinones such as linezolid and tedizolid are considered potential treatment choices for conditions involving ...
Moritz Staudacher, Julian Frederic Hotz, Richard Kriz, Katharina Schefberger, Lisa Schneider, Kathrin Spettel, Peter Starzengruber, Jürgen Benjamin Hagemann, Amelie Leutzendorff, Heinz Burgmann, Heimo Lagler   +10 more
doaj   +1 more source

Non‐Reductive CO2 Valorization into Oxazolidinones via Cycloaddition to Aziridines: A Personal Insight

European Journal of Organic Chemistry, Volume 27, Issue 39, October 14, 2024.
This perspective provides an overview of recent homogeneous and heterogeneous catalytic methodologies published on the CO2 cycloaddition to aziridines to form oxazolidinones, with a particular attention to the employed experimental conditions, which are essential parameters for envisioning real costs and possible applications of these synthetic ...
Caterina Damiano, Matteo Cavalleri, Lucia Invernizzi, Emma Gallo   +3 more
wiley   +1 more source

In vitro Antimicrobial Activity Comparison of Linezolid, Tedizolid, Sutezolid and Delpazolid Against Slowly Growing Mycobacteria Isolated in Beijing, China

Infection and Drug Resistance, 2021
Xia Yu,* Fengmin Huo,* Fen Wang,* Shu’an Wen, Guanglu Jiang, Yi Xue, Lingling Dong, Liping Zhao, Rui Zhu, Hairong Huang National Clinical Laboratory on Tuberculosis, Beijing Key Laboratory for Drug-Resistant Tuberculosis Research, Beijing ...
Yu X, Huo F, Wang F, Wen S, Jiang G, Xue Y, Dong L, Zhao L, Zhu R, Huang H   +9 more
doaj  

Pulmonary nocardiosis treated with tedizolid.

Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria, 2019
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José María Gutiérrez-Urbón, Víctor Giménez-Arufe, Marina Blanco-Aparicio, Enrique Míguez-Rey, María Isabel Martín-Herranz   +4 more
openaire   +3 more sources