Results 71 to 80 of about 1,717 (156)

Oxidative stress is two‐sided in the treatment of acute myeloid leukemia

Cancer Medicine, Volume 13, Issue 9, May 2024.
Abstract Introduction Oxidative stress caused by elevated ROS, as a novel therapeutic mechanism, has been implicated in various tumors including AML. AML cells are chronically under oxidative stress, yet overreliance on ROS production makes tumor cells increasingly vulnerable to further damage. Reducing the cytotoxic effect of ROS on normal cells while
Chenyang Fan, Xiangdong Yang, Lixiang Yan, Zhexin Shi   +3 more
wiley   +1 more source

Update on chiral recognition mechanisms in separation science

Journal of Separation Science, Volume 47, Issue 9-10, May 2024.
The stereospecific analysis of chiral molecules is an important issue in many scientific fields. In separation sciences, this is achieved via the formation of transient diastereomeric complexes between a chiral selector and the selectand enantiomers driven by molecular interactions including electrostatic, ion‐dipole, dipole‐dipole, van der Waals or π ...
Gerhard K. E. Scriba
wiley   +1 more source

Predictive Modeling of Drug‐Related Adverse Events with Real‐World Data: A Case Study of Linezolid Hematologic Outcomes

Clinical Pharmacology &Therapeutics, Volume 115, Issue 4, Page 847-859, April 2024.
Electronic health records (EHRs) provide meaningful knowledge of drug‐related adverse events (AEs) that are not captured in standard drug development and postmarketing surveillance. Using variables obtained from EHR data in the University of California San Francisco de‐identified Clinical Data Warehouse, we aimed to evaluate the potential of machine ...
Anu Patel, Sarah B. Doernberg, Travis Zack, Atul J. Butte, Kendra K. Radtke   +4 more
wiley   +1 more source

Potential of the Introduction of Tedizolid for the Treatment of Complicated Skin and Soft Tissue Infections in a Russian Multi-Field Hospital [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2016
Increase in prevalence of methicillin-resistant Staphylococcus aureus (MRSA) strains among the pathogens of complicated skin and soft tissue infections (cSSTIs) in hospitalised patients demands introduction of new treatment options with improved efficacy
Belkova Yu.А., Rachina S.A., Kozlov R.S., Golub A.V., Portnyagina U.S., Shamaev S.H.   +5 more
doaj  

Comparison of Anti-Microbic and Anti-Biofilm Activity Among Tedizolid and Radezolid Against Linezolid-Resistant Enterococcus faecalis Isolates

Infection and Drug Resistance, 2021
Lingbo Wang,1,* Ying Zhang,2,* Shixing Liu,1 Na Huang,1 Weiliang Zeng,1 Wenya Xu,1 Tieli Zhou,1 Mo Shen1 1Department of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, People’s ...
Wang L, Zhang Y, Liu S, Huang N, Zeng W, Xu W, Zhou T, Shen M   +7 more
doaj  

Acute bacterial skin and soft tissue infections: new drugs in ID armamentarium

Journal of Community Hospital Internal Medicine Perspectives, 2019
Acute bacterial skin and soft tissue infections (SSTI) are among the most common reasons for hospitalization of adults in the USA today. Cellulitis or SSTI can cause significant morbidity and mortality.
Raghavendra Tirupathi, Swetha Areti, Sohail A. Salim, Venkatraman Palabindala, Nageshwar Jonnalagadda   +4 more
doaj   +1 more source

Critical role of tedizolid in the treatment of acute bacterial skin and skin structure infections

Drug Design, Development and Therapy, 2016
Olivia Ferrández,1,2 Olatz Urbina,1 Santiago Grau1,3 1Hospital Pharmacy, Hospital Universitari del Mar, Barcelona, Spain; 2Nursing Department, Universitat Pompeu Fabra, Barcelona, Spain; 3Medicine Department, Universitat Autònoma de ...
Ferrández O, Urbina O, Grau S
doaj  

Current Problems of Infections Caused by MRSA and Ways to Address Them

Антибиотики и Химиотерапия, 2020
The increase in the growth rate of MRSA as an etiologic factor has been recorded worldwide in recent years. The main problem of antibiotic resistance in Staphylococcus aureus is its resistance to beta-lactam antibiotics.
S. K. Zyryanov, I. N. Sychev, Yu. Sh. Gushchina   +2 more
doaj  

Antibiotic Resistance to Molecules Commonly Prescribed for the Treatment of Antibiotic-Resistant Gram-Positive Pathogens: What Is Relevant for the Clinician?

Pathogens
Antibiotic resistance in Gram-positive pathogens is a relevant concern, particularly in the hospital setting. Several antibiotics are now available to treat these drug-resistant pathogens, such as daptomycin, dalbavancin, linezolid, tedizolid ...
Gianpiero Tebano, Irene Zaghi, Francesco Baldasso, Chiara Calgarini, Roberta Capozzi, Caterina Salvadori, Monica Cricca, Francesco Cristini   +7 more
doaj   +1 more source

Tedizolid for Treatment of Enterococcal Bacteremia [PDF]

Open Forum Infectious Diseases, 2016
Praveen Sudhindra, Leslie Lee, Guiqing Wang, Abhay Dhand   +3 more
openaire   +1 more source