Results 111 to 120 of about 570,627 (165)

Regulation of telomerase reverse transcriptase expression in Schizosaccharomyces pombe [PDF]

, 2013
Eukaryotic cells undergo chromosome shortening during each cell division due to the inability of DNA polymerase to replicate chromosome ends. This end replication problem is counteracted by the ribonucleoprotein telomerase, which functions as a reverse ...
Janzen, Evan Paul
core   +1 more source

Human telomerase reverse transcriptase supports respiratory syncytial virus replication

Communications Biology
Respiratory syncytial virus (RSV), discovered in 1956 and identified in children in 1957, is the major respiratory pathogen of infants and children under the age of 5 worldwide.
HoangDinh Huynh, Chien-Ting Wu, Jeffrey S. Kahn   +2 more
doaj   +1 more source

Telomerase Reverse Transcriptase and Wnt Signaling [PDF]

Molecular and Cellular Biology, 2011
openaire   +2 more sources

Telomerase reverse transcriptase (TERT) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Mitochondrial Telomerase Reverse Transcriptase, a Target for Cardiovascular Disease?

Function, 2022
Keiichi Torimoto, Satoru Eguchi
doaj   +1 more source

Telomerase reverse transcriptase (TERT) [PDF]

Science-Business eXchange, 2013
openaire   +1 more source

Telomerase reverse transcriptase (TERT) [PDF]

Science-Business eXchange, 2008
openaire   +1 more source

Cancer immunotherapy targeting the telomerase reverse transcriptase.

, 2006
The human telomerase reverse transcriptase (hTERT) is expressed in more than 85% of tumor cells but is usually not found in normal cells, which makes hTERT as an ideal tumor-associate antigen (TAA) to develop potential vaccine specifically destroying ...
Lin, MC, Tang, JW, Kung, HF, Huo, LF, Huang, JJ, Huang, CF, Huang, PT   +6 more
core  

Telomerase is a true reverse transcriptase. A review

Synthesis of telomeric repeats at chromosome ends requires telomerase, a ribonucleoprotein enzyme. The RNA subunit, which contains the template for DNA synthesis, has been identified in many organisms.
Cech, T. R., Nakamura, T. M., Lingner, J.   +2 more
core  

Possible Regulation of Telomerase Activity by Transcription and Alternative Splicing of Telomerase Reverse Transcriptase in Human Melanoma [PDF]

Journal of Investigative Dermatology, 2001
To investigate the regulatory mechanisms of telomerase activity in human melanoma cells, we assessed the enzyme's catalytic activity and the expression of the telomerase subunits, the human telomerase RNA, the human telomerase-associated protein, and the
Marco Folini, Nadia Zaffaroni, Maria Grazia Daidone   +2 more
exaly   +2 more sources