Results 11 to 20 of about 77,771 (318)

Euplotes crassushas genes encoding telomere-binding proteins and telomere-binding protein homologs [PDF]

open access: bronzeNucleic Acids Research, 1992
We have identified two 1.6 kb macronuclear DNA molecules from Euplotes crassus that hybridize to the alpha subunit of the Oxytricha telomere protein. We have shown that one of these molecules encodes the 51 kDa Euplotes telomere protein while the other appears to encode a homolog of the telomere protein.
Wenlan Wang   +3 more
openalex   +4 more sources

HYPOTHESIS: PARALOG FORMATION FROM PROGENITOR PROTEINS AND PARALOG MUTAGENESIS SPUR THE RAPID EVOLUTION OF TELOMERE BINDING PROTEINS [PDF]

open access: yesFrontiers in Genetics, 2016
Through elegant studies in fungal cells and complex organisms, we propose a unifying paradigm for the rapid evolution of telomere binding proteins (TBPs) that associate with either (or both) telomeric DNA and telomeric proteins.
Arthur J Lustig
doaj   +2 more sources

Defining the chromatin-associated protein landscapes on Trypanosoma brucei repetitive elements using synthetic TALE proteins [PDF]

open access: yeseLife
Kinetoplastids, such as Trypanosoma brucei, are eukaryotes that likely separated from the main lineage at an exceptionally early point in evolution. Consequently, many aspects of kinetoplastid biology differ significantly from other eukaryotic model ...
Roberta Carloni   +7 more
doaj   +2 more sources

Molecular cloning of telomere-binding protein gens fromStylonchia mytilis [PDF]

open access: bronzeNucleic Acids Research, 1991
A telomere-binding protein heterodimer of 56 kDa (alpha) and 41 kDa (beta) subunits binds specifically to Oxytricha nova telomeres. Genes encoding both subunits have been cloned previously. Here we report molecular cloning and sequence analysis of the homologous genes in Stylonychia mytilis.
Guowei Fang, Thomas R. Cech
openalex   +4 more sources

Telomeric repeats facilitate CENP-A(Cnp1) incorporation via telomere binding proteins.

open access: yesPLoS ONE, 2013
The histone H3 variant, CENP-A, is normally assembled upon canonical centromeric sequences, but there is no apparent obligate coupling of sequence and assembly, suggesting that centromere location can be epigenetically determined.
Araceli G Castillo   +7 more
doaj   +3 more sources

At Short Telomeres Tel1 Directs Early Replication and Phosphorylates Rif1 [PDF]

open access: yes, 2014
Funding AS was supported by a Cancer Research UK PhD studentship and ORSAS. SK is supported by a Scottish Universities Life Sciences Alliance PhD studentship.
Donaldson, Anne D.   +2 more
core   +15 more sources

Plasmodium falciparum GBP2 Is a Telomere-Associated Protein That Binds to G-Quadruplex DNA and RNA

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
In the early-diverging protozoan parasite Plasmodium, few telomere-binding proteins have been identified and several are unique. Plasmodium telomeres, like those of most eukaryotes, contain guanine-rich repeats that can form G-quadruplex structures.
James Edwards-Smallbone   +5 more
doaj   +1 more source

The Saccharomyces cerevisiae telomerase subunit Est3 binds telomeres in a cell cycle- and Est1-dependent manner and interacts directly with Est1 in vitro. [PDF]

open access: yesPLoS Genetics, 2011
Telomerase is a telomere dedicated reverse transcriptase that replicates the very ends of eukaryotic chromosomes. Saccharomyces cerevisiae telomerase consists of TLC1 (the RNA template), Est2 (the catalytic subunit), and two accessory proteins, Est1 and ...
Creighton T Tuzon   +3 more
doaj   +1 more source

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