List of putative telomere-binding proteins identified by in silico analysis of the corresponding fungal genomes (see also Fig 1). [PDF]
, 2016 List of putative telomere-binding proteins identified by in silico analysis of the corresponding fungal genomes (see also Fig 1).
Lubomir Tomaska (2622682) +8 more
core +1 more source
Telomere-binding proteins play roles in control of replication timing [PDF]
Cell Cycle, 2012 Comment on: Tazumi A, et al. Genes Dev 2012; 26:2050-62.
Tazumi, Atsutoshi, Masukata, Hisao
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Characterization of a Telomere-Binding Protein from Physarum polycephalum [PDF]
Molecular and Cellular Biology, 1991 We have partially purified a nuclear protein (PPT) from Physarum polycephalum that binds to the extrachromosomal ribosomal DNA telomeres of this acellular slime mold. Binding is specific for the (T2AG3)n telomere repeats, as evidenced by nitrocellulose filter binding assays, by gel mobility shift assays with both DNA fragments and double-stranded ...
J S, Coren, E M, Epstein, V M, Vogt
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Telomere-binding proteins spread to the seeded subtelomere in HeLa cells. [PDF]
, 2014 A. Dot blots of chromatin immunoprecipitates indicating specificity of telomere-binding proteins. Left, the telomere-repeat probe. Right, the alphoid probe. Results shown are from three independent immunoprecipitation experiments (ChIP #1-#3). B.
Satoshi Abe (524075) +4 more
core +1 more source
Telomere binding of the Rap1 protein is required for meiosis in fission yeast [PDF]
Current Biology, 2001 Telomeres are essential for chromosome integrity, protecting the ends of eukaryotic linear chromosomes during cell proliferation. Telomeres also function in meiosis; a characteristic clustering of telomeres beneath the nuclear membrane is observed during meiotic prophase in many organisms from yeasts to plants and humans, and the role of the telomeres ...
Chikashige, Yuji, Hiraoka, Yasushi
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The effect of chemotherapeutic agents on telomere length maintenance in breast cancer cell lines [PDF]
, 2014 Copyright @ 2014 the authors. This article is made available through the Brunel Open Access Publishing Fund. It is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution ...
Slijepcevic, P +9 more
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TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
Hepatology, EarlyView., 2022 The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam +10 more
wiley +1 more source
Functional Studies of Telomere-Binding Proteins in Saccharomyces castellii [PDF]
, 2009 Telomeres are the ends of linear eukaryotic chromosomes. The telomeres are essential for solving the end replication problem and they stabilize the genome by protection from degradation.
Lund University., Rhodin, Jenny,
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Swi1Timeless Prevents Repeat Instability at Fission Yeast Telomeres. [PDF]
PLoS Genetics, 2016 Genomic instability associated with DNA replication stress is linked to cancer and genetic pathologies in humans. If not properly regulated, replication stress, such as fork stalling and collapse, can be induced at natural replication impediments present
Mariana C Gadaleta +6 more
doaj +1 more source
Ku80 facilitates chromatin binding of the telomere binding protein, TRF2 [PDF]
Cell Cycle, 2010 The Ku70/80 heterodimer is central to non-homologous end joining repair of DNA double-strand breaks and the Ku80 gene appears to be essential for human but not rodent cell survival. The Ku70/80 heterodimer is located at telomeres but its precise function in telomere maintenance is not known.
Lauren S, Fink +3 more
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