Results 21 to 30 of about 21,644 (273)
Posttransplant Tertiary Lymphoid Organs. [PDF]
Transplantation, 2023 Tertiary lymphoid organs (TLOs), also known as tertiary or ectopic lymphoid structures or tissues, are accumulations of lymphoid cells in sites other than canonical lymphoid organs, that arise through lymphoid neogenesis during chronic inflammation in autoimmunity, microbial infection, cancer, aging, and transplantation, the focus of this review. Lymph
Ruddle NH.
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Tertiary Lymphoid Organs in Cancer Tissues. [PDF]
Front Immunol, 2016 Tertiary lymphoid organs (TLOs) are induced postnatally in non-lymphoid tissues such as those affected by chronic infections, autoimmune diseases, and chronic allograft rejection, and also in cancer tissues. TLOs are thought to provide important lymphocytic functional environments for both cellular and humoral immunity, similar to lymph nodes or Peyer ...
Hiraoka N, Ino Y, Yamazaki-Itoh R.
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Lymphoid Neogenesis and Tertiary Lymphoid Organs in Transplanted Organs. [PDF]
Front Immunol, 2016 The progressive organization of immune effectors into functional ectopic lymphoid structures, named tertiary lymphoid organs (TLO), has been observed in many conditions in which target antigens fail to be eliminated by the immune system. Not surprisingly, TLO have been recurrently identified in chronically rejected allografts.
Koenig A, Thaunat O.
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A Unique Cellular and Molecular Microenvironment Is Present in Tertiary Lymphoid Organs of Patients with Spontaneous Prostate Cancer Regression. [PDF]
Front Immunol, 2017 García-Hernández ML +5 more
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Orchestration of tertiary lymphoid structures: decoding developmental mechanisms for next-generation cancer immunotherapies [PDF]
Medical ReviewTertiary lymphoid structures (TLSs) are ectopic lymphoid aggregates that form in non-lymphoid organs, frequently observed in conditions such as cancer, autoimmune diseases, transplant rejection, and chronic inflammation.
Hao Wenqin, Zhao Ying
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Identification and characterisation of tertiary lymphoid organs in human type 1 diabetes. [PDF]
Diabetologia, 2021 AbstractAims/hypothesisWe and others previously reported the presence of tertiary lymphoid organs (TLOs) in the pancreas of NOD mice, where they play a role in the development of type 1 diabetes. Our aims here are to investigate whether TLOs are present in the pancreas of individuals with type 1 diabetes and to characterise their distinctive features ...
Korpos É +10 more
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Lymphatic vessels and tertiary lymphoid organs. [PDF]
J Clin Invest, 2014 Tertiary lymphoid organs (TLOs) are accumulations of lymphoid cells in chronic inflammation that resemble LNs in their cellular content and organization, high endothelial venules, and lymphatic vessels (LVs). Although acute inflammation can result in defective LVs, TLO LVs appear to function normally in that they drain fluid and transport cells that ...
Ruddle NH.
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Tertiary lymphoid organs in lymphatic malformations. [PDF]
Lymphat Res Biol, 2011 Examine lymphatic malformation lymphoid aggregates for the expression of tertiary lymphoid organ markers. Determine how lymphoid aggregate density relates to lymphatic malformation clinical features.Retrospective cohort study. Tissue and clinical data were reviewed from 29 patients in the Vascular Anomaly Database who represented the spectrum of head ...
Kirsh AL +4 more
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Colitis and Colorectal Carcinogenesis: The Focus on Isolated Lymphoid Follicles
Biomedicines, 2022 Gut-associated lymphoid tissue is one of the most diverse and complex immune compartments in the human body. The subepithelial compartment of the gut consists of immune cells of innate and adaptive immunity, non-hematopoietic mesenchymal cells, and stem ...
Györgyi Műzes +2 more
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Tertiary Lymphoid Organs in Rheumatoid Arthritis [PDF]
, 2020 Rheumatoid Arthritis (RA) is a chronic systemic autoimmune disease. RA mainly affects the joints, with inflammation of the synovial membrane, characterized by hyperplasia, neo-angiogenesis, and immune cell infiltration that drives local inflammation and, if untreated, can lead to joint destruction and disability.
Rivellese, F, Pontarini, E, Pitzalis, C
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