Results 31 to 40 of about 9,564 (122)

Tertiary lymphoid organs in lymphatic malformations. [PDF]

Lymphat Res Biol, 2011
Examine lymphatic malformation lymphoid aggregates for the expression of tertiary lymphoid organ markers. Determine how lymphoid aggregate density relates to lymphatic malformation clinical features.Retrospective cohort study. Tissue and clinical data were reviewed from 29 patients in the Vascular Anomaly Database who represented the spectrum of head ...
Kirsh AL, Cushing SL, Chen EY, Schwartz SM, Perkins JA.   +4 more
europepmc   +4 more sources

The roles of tertiary lymphoid structures in orchestrating immune responses in peripheral organs

Inflammation and Regeneration
Tertiary lymphoid structures (TLSs) are ectopic lymphoid aggregates that develop in non-lymphoid organs under pathological conditions of chronic inflammation, such as cancer, autoimmune diseases, chronic infections, organ transplantation, and age-related
Keisuke Taniguchi, Takahisa Yoshikawa, Motoko Yanagita   +2 more
doaj   +4 more sources

Tertiary lymphoid organs in infection and autoimmunity. [PDF]

Trends Immunol, 2012
The lymph nodes (LNs) and spleen have an optimal structure that allows the interaction between T cells, B cells and antigen-presenting dendritic cells (DCs) on a matrix made up by stromal cells. Such a highly organized structure can also be formed in tertiary lymphoid organs (TLOs) at sites of infection or chronic immune stimulation.
Neyt K, Perros F, GeurtsvanKessel CH, Hammad H, Lambrecht BN.   +4 more
europepmc   +5 more sources

Tertiary lymphoid organs in recalcitrant chronic rhinosinusitis [PDF]

Journal of Allergy and Clinical Immunology, 2017
The letter to the editor. ; Abstract not available ; Aden Lau, Susan Lester, Sophia Moraitis, Judy Ou, Alkis J.
Lau, A., Lester, S., Moraitis, S., Ou, J., Psaltis, A., McColl, S., Rischmueller, M., Wormald, P., Vreugde, S.   +8 more
openaire   +3 more sources

Tertiary Lymphoid Structures and Cancer Prognosis (Brief Review)

Креативная хирургия и онкология, 2020
This brief review is devoted to the role of tertiary lymphoid structures in oncological processes. A number of research studies carried out over the past ten years have shed light on the functions of such structures in various diseases, as well as their ...
R. A. Rustamkhanov, K. Sh. Gantsev, D. S. Tursumetov   +2 more
doaj   +1 more source

Identification of novel genes associated with renal tertiary lymphoid organ formation in aging mice. [PDF]

PLoS ONE, 2014
A hallmark of aging-related organ deterioration is a dysregulated immune response characterized by pathologic leukocyte infiltration of affected tissues. Mechanisms and genes involved are as yet unknown.
Yuan Huang, Christina R Caputo, Gerda A Noordmans, Saleh Yazdani, Luiz Henrique Monteiro, Jaap van den Born, Harry van Goor, Peter Heeringa, Ron Korstanje, Jan-Luuk Hillebrands   +9 more
doaj   +1 more source

B cells and tertiary lymphoid organs in renal inflammation [PDF]

Kidney International, 2008
B lymphocytes are part of the inflammatory cells recruited to the human kidney in various disease settings. B cell infiltrates have been described in renal allografts, in acute and chronic interstitial nephritis, and the most common glomerular diseases like immunoglobulin A (IgA) and membranous nephropathy.
Segerer, S., Schlöndorff, D.
openaire   +2 more sources

[Induction and Anti-Tumor Function of Tertiary Lymphoid Organs]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban, 2022
To induce the development of tertiary lymphoid organs (TLO) in a mouse model of melanoma and to evaluate TLO's functions in antitumor immunity.Lymphotoxin-beta receptor (LTβR) was overexpressed in NIH3T3 cells through the lentivirus system and the overexpression efficiency of LTβR in LTβR-NIH3T3 cells was examined.
Chen H, Hu X, Zhang HY, Hu HB.
europepmc   +3 more sources

The expansion in lymphoid organs of IL-4 + BATF + T follicular helper cells is linked to IgG4 class switching in vivo

Life Science Alliance, 2018
T follicular helper cells that secrete IL-4 accumulate in lymphoid organs in IgG4-related disease and are linked to IgG4 class switching. Distinct T follicular helper (T FH ) subsets that influence specific class-switching events are assumed to exist ...
Takashi Maehara, Hamid Mattoo, Vinay S Mahajan, Samuel JH Murphy, Grace J Yuen, Noriko Ishiguro, Miho Ohta, Masafumi Moriyama, Takako Saeki, Hidetaka Yamamoto, Masaki Yamauchi, Joe Daccache, Tamotsu Kiyoshima, Seiji Nakamura, John H Stone, Shiv Pillai   +15 more
doaj   +1 more source

Tertiary lymphoid structures and B lymphocytes in cancer prognosis and response to immunotherapies

OncoImmunology, 2021
Tertiary lymphoid structures (TLS) are ectopic cellular aggregates that resemble secondary lymphoid organs in their composition and structural organization.
Jacquelot N, Tellier J, Nutt Sl, Belz Gt
doaj   +1 more source