Disordered Balance of T‐Cell Subsets in Arterial Tertiary Lymphoid Organs in Immunoglobulin G4–Related Vascular Disease [PDF]
Journal of the American Heart Association, 2023 Satomi Kasashima +2 more
exaly +2 more sources
Posttransplant Tertiary Lymphoid Organs. [PDF]
Transplantation, 2023 Tertiary lymphoid organs (TLOs), also known as tertiary or ectopic lymphoid structures or tissues, are accumulations of lymphoid cells in sites other than canonical lymphoid organs, that arise through lymphoid neogenesis during chronic inflammation in autoimmunity, microbial infection, cancer, aging, and transplantation, the focus of this review. Lymph
Ruddle NH.
europepmc +3 more sources
Role of tertiary lymphoid organs in the regulation of immune responses in the periphery. [PDF]
Cell Mol Life Sci, 2022 Tertiary lymphoid organs (TLOs) are collections of immune cells resembling secondary lymphoid organs (SLOs) that form in peripheral, non-lymphoid tissues in response to local chronic inflammation. While their formation mimics embryologic lymphoid organogenesis, TLOs form after birth at ectopic sites in response to local inflammation resulting in their ...
Bery AI +5 more
europepmc +3 more sources
Identification and characterisation of tertiary lymphoid organs in human type 1 diabetes. [PDF]
Diabetologia, 2021 AbstractAims/hypothesisWe and others previously reported the presence of tertiary lymphoid organs (TLOs) in the pancreas of NOD mice, where they play a role in the development of type 1 diabetes. Our aims here are to investigate whether TLOs are present in the pancreas of individuals with type 1 diabetes and to characterise their distinctive features ...
Korpos É +10 more
europepmc +4 more sources
Lymphatic vessels and tertiary lymphoid organs. [PDF]
J Clin Invest, 2014 Tertiary lymphoid organs (TLOs) are accumulations of lymphoid cells in chronic inflammation that resemble LNs in their cellular content and organization, high endothelial venules, and lymphatic vessels (LVs). Although acute inflammation can result in defective LVs, TLO LVs appear to function normally in that they drain fluid and transport cells that ...
Ruddle NH.
europepmc +4 more sources
Mitochondrial One-Carbon Metabolism Drives CD34-Lineage Cells to Differentiate Into T Follicular Helper Cells to Form Tertiary Lymphoid Organs in Transplant Arteriosclerosis [PDF]
CirculationChunyan Weng, Qin Li, Qingzhong Xiao
exaly +2 more sources
Tertiary Lymphoid Organs in Rheumatoid Arthritis [PDF]
, 2020 Rheumatoid Arthritis (RA) is a chronic systemic autoimmune disease. RA mainly affects the joints, with inflammation of the synovial membrane, characterized by hyperplasia, neo-angiogenesis, and immune cell infiltration that drives local inflammation and, if untreated, can lead to joint destruction and disability.
Rivellese, F, Pontarini, E, Pitzalis, C
openaire +3 more sources
Colitis and Colorectal Carcinogenesis: The Focus on Isolated Lymphoid Follicles
Biomedicines, 2022 Gut-associated lymphoid tissue is one of the most diverse and complex immune compartments in the human body. The subepithelial compartment of the gut consists of immune cells of innate and adaptive immunity, non-hematopoietic mesenchymal cells, and stem ...
Györgyi Műzes +2 more
doaj +1 more source
Editorial: Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity. [PDF]
Front Immunol, 2017 No abstract available.
Yin C +3 more
europepmc +7 more sources
Tertiary Lymphoid Organs at the Center Stage of Skin's Humoral Immunity. [PDF]
Immunol RevABSTRACTThe skin is the outermost organ that serves as the host's live, microbiota‐inhabited physical border, evolved to cope with continuous confrontation by a wide variety of environmental elements. This dynamic borderline is prone to injury and damage.
Gribonika I.
europepmc +3 more sources