Role of tertiary lymphoid organs in the regulation of immune responses in the periphery. [PDF]
Cell Mol Life Sci, 2022 Tertiary lymphoid organs (TLOs) are collections of immune cells resembling secondary lymphoid organs (SLOs) that form in peripheral, non-lymphoid tissues in response to local chronic inflammation. While their formation mimics embryologic lymphoid organogenesis, TLOs form after birth at ectopic sites in response to local inflammation resulting in their ...
Bery AI +5 more
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B Cell Activating Factor (BAFF) Is Required for the Development of Intra-Renal Tertiary Lymphoid Organs in Experimental Kidney Transplantation in Rats [PDF]
International Journal of Molecular Sciences, 2020 Antonia Schuster +2 more
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Identification and characterisation of tertiary lymphoid organs in human type 1 diabetes. [PDF]
Diabetologia, 2021 AbstractAims/hypothesisWe and others previously reported the presence of tertiary lymphoid organs (TLOs) in the pancreas of NOD mice, where they play a role in the development of type 1 diabetes. Our aims here are to investigate whether TLOs are present in the pancreas of individuals with type 1 diabetes and to characterise their distinctive features ...
Korpos É +10 more
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Tertiary Lymphoid Organs Are Associated With Bacterial Dysbiosis in Chronic Rhinosinusitis. [PDF]
Int Forum Allergy RhinolISSN:2042 ...
Paramasivan S +9 more
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Lymphatic vessels and tertiary lymphoid organs. [PDF]
J Clin Invest, 2014 Tertiary lymphoid organs (TLOs) are accumulations of lymphoid cells in chronic inflammation that resemble LNs in their cellular content and organization, high endothelial venules, and lymphatic vessels (LVs). Although acute inflammation can result in defective LVs, TLO LVs appear to function normally in that they drain fluid and transport cells that ...
Ruddle NH.
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Tertiary Lymphoid Organs in Rheumatoid Arthritis [PDF]
, 2020 Rheumatoid Arthritis (RA) is a chronic systemic autoimmune disease. RA mainly affects the joints, with inflammation of the synovial membrane, characterized by hyperplasia, neo-angiogenesis, and immune cell infiltration that drives local inflammation and, if untreated, can lead to joint destruction and disability.
Rivellese, F, Pontarini, E, Pitzalis, C
openaire +3 more sources
Colitis and Colorectal Carcinogenesis: The Focus on Isolated Lymphoid Follicles
Biomedicines, 2022 Gut-associated lymphoid tissue is one of the most diverse and complex immune compartments in the human body. The subepithelial compartment of the gut consists of immune cells of innate and adaptive immunity, non-hematopoietic mesenchymal cells, and stem ...
Györgyi Műzes +2 more
doaj +1 more source
Editorial: Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity. [PDF]
Front Immunol, 2017 No abstract available.
Yin C +3 more
europepmc +7 more sources
Tertiary lymphoid organs in lymphatic malformations. [PDF]
Lymphat Res Biol, 2011 Examine lymphatic malformation lymphoid aggregates for the expression of tertiary lymphoid organ markers. Determine how lymphoid aggregate density relates to lymphatic malformation clinical features.Retrospective cohort study. Tissue and clinical data were reviewed from 29 patients in the Vascular Anomaly Database who represented the spectrum of head ...
Kirsh AL +4 more
europepmc +4 more sources
Tertiary lymphoid organs in infection and autoimmunity. [PDF]
Trends Immunol, 2012 The lymph nodes (LNs) and spleen have an optimal structure that allows the interaction between T cells, B cells and antigen-presenting dendritic cells (DCs) on a matrix made up by stromal cells. Such a highly organized structure can also be formed in tertiary lymphoid organs (TLOs) at sites of infection or chronic immune stimulation.
Neyt K +4 more
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