Tertiary Lymphoid Organs in Cancer Tissues. [PDF]
Tertiary lymphoid organs (TLOs) are induced postnatally in non-lymphoid tissues such as those affected by chronic infections, autoimmune diseases, and chronic allograft rejection, and also in cancer tissues. TLOs are thought to provide important lymphocytic functional environments for both cellular and humoral immunity, similar to lymph nodes or Peyer ...
Hiraoka N, Ino Y, Yamazaki-Itoh R.
europepmc +4 more sources
Mitochondrial One-Carbon Metabolism Drives CD34-Lineage Cells to Differentiate Into T Follicular Helper Cells to Form Tertiary Lymphoid Organs in Transplant Arteriosclerosis [PDF]
Yao Lu, Qingzhong Xiao, Jingjing Cai
exaly +2 more sources
High efficacy therapy to prevent the formation of meningeal tertiary lymphoid organs after CXCL13 index screening in early multiple sclerosis [PDF]
Ana C Londoño, Carlos A Mora
exaly +2 more sources
Tertiary Lymphoid Organs Are Associated With Bacterial Dysbiosis in Chronic Rhinosinusitis. [PDF]
ISSN:2042 ...
Paramasivan S +9 more
europepmc +5 more sources
Lymphatic vessels and tertiary lymphoid organs. [PDF]
Tertiary lymphoid organs (TLOs) are accumulations of lymphoid cells in chronic inflammation that resemble LNs in their cellular content and organization, high endothelial venules, and lymphatic vessels (LVs). Although acute inflammation can result in defective LVs, TLO LVs appear to function normally in that they drain fluid and transport cells that ...
Ruddle NH.
europepmc +4 more sources
Tertiary Lymphoid Organs in Rheumatoid Arthritis [PDF]
Rheumatoid Arthritis (RA) is a chronic systemic autoimmune disease. RA mainly affects the joints, with inflammation of the synovial membrane, characterized by hyperplasia, neo-angiogenesis, and immune cell infiltration that drives local inflammation and, if untreated, can lead to joint destruction and disability.
Rivellese, F, Pontarini, E, Pitzalis, C
openaire +3 more sources
Colitis and Colorectal Carcinogenesis: The Focus on Isolated Lymphoid Follicles
Gut-associated lymphoid tissue is one of the most diverse and complex immune compartments in the human body. The subepithelial compartment of the gut consists of immune cells of innate and adaptive immunity, non-hematopoietic mesenchymal cells, and stem ...
Györgyi Műzes +2 more
doaj +1 more source
Tertiary lymphoid organs in infection and autoimmunity [PDF]
The lymph nodes (LNs) and spleen have an optimal structure that allows the interaction between T cells, B cells and antigen-presenting dendritic cells (DCs) on a matrix made up by stromal cells. Such a highly organized structure can also be formed in tertiary lymphoid organs (TLOs) at sites of infection or chronic immune stimulation.
Katrijn Neyt +4 more
openaire +3 more sources
The roles of tertiary lymphoid structures in orchestrating immune responses in peripheral organs
Tertiary lymphoid structures (TLSs) are ectopic lymphoid aggregates that develop in non-lymphoid organs under pathological conditions of chronic inflammation, such as cancer, autoimmune diseases, chronic infections, organ transplantation, and age-related
Keisuke Taniguchi +2 more
doaj +4 more sources
Editorial: Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity. [PDF]
No abstract available.
Yin C +3 more
europepmc +7 more sources

