Results 41 to 50 of about 9,564 (122)

IL-17 initiates tertiary lymphoid organ formation [PDF]

open access: yesCellular & Molecular Immunology, 2011
Chronic inflammatory infiltrates that take on the form of organized lymphoid organs are called tertiary lymphoid organs (TLOs). The inflammatory cytokine interleukin-17 is now found to be the critical participant driving the development of a type of TLO called inducible bronchus-associated lymphoid tissue (iBALT) in an animal model of neonatal ...
Xueguang, Zhang, Binfeng, Lu
openaire   +2 more sources

Understanding Immune Cells in Tertiary Lymphoid Organ Development: It’s All Starting to Come Together

open access: yesFrontiers in Immunology, 2016
Tertiary lymphoid organs (TLOs) are frequently observed in tissues affected by non-resolving inflammation as a result of infection, autoimmunity, cancer and allograft rejection.
Gareth Wyn Jones   +2 more
doaj   +1 more source

Recent Progress of Tertiary Lymphoid Structure in Prognosis and Immunotherapy of Non-small Cell Lung Cancer

open access: yesChinese Journal of Lung Cancer, 2023
Lung cancer is the leading cause of cancer death, and non-small cell lung cancer (NSCLC) accounts for 85%. Immunotherapy has significantly improved the clinical prognosis of patients with NSCLC. However, because of the complexity and heterogeneousness of
Ying LIU   +6 more
doaj   +1 more source

Tertiary Lymphoid Structures: Autoimmunity Goes Local

open access: yesFrontiers in Immunology, 2018
Tertiary lymphoid structures (TLS) are frequently observed in target organs of autoimmune diseases. TLS present features of secondary lymphoid organs such as segregated T and B cell zones, presence of follicular dendritic cell networks, high endothelial ...
Elena Pipi   +6 more
doaj   +1 more source

Tertiary lymphoid structures are critical for cancer prognosis and therapeutic response

open access: yesFrontiers in Immunology, 2023
Tertiary lymphoid structures (TLSs) are ectopic lymphocyte aggregates that form at sites of chronic inflammation, including cancers, in non-lymphoid tissues.
Qianqian Zhang, Suhui Wu
doaj   +1 more source

Follicular dendritic cells, conduits, lymphatic vessels, and high endothelial venules in tertiary lymphoid organs: Parallels with lymph node stroma

open access: yesFrontiers in Immunology, 2012
In this communication, the contribution of stromal, or non-hematopoietic, cells to the structure and function of lymph nodes (LNs), as canonical secondary lymphoid organs (SLOs), is compared to that of tertiary lymphoid tissue or organs (TLOs), also ...
Sharon eStranford, Nancy H. Ruddle
doaj   +1 more source

Tertiary lymphoid structures in gynecological cancers: prognostic role, methods for evaluating, antitumor immunity, and induction for therapy

open access: yesFrontiers in Oncology, 2023
Tertiary lymphoid structures (TLSs), referred to as tertiary lymphoid organs and lymphoid tissue neogenesis, are aggregates of immune cells that occur in nonlymphoid tissues.
Ke Zhang   +12 more
doaj   +1 more source

IL-17, a new kid on the block of tertiary lymphoid organs [PDF]

open access: yesCellular & Molecular Immunology, 2011
Tertiary lymphoid organs (TLOs) are structures that resemble lymph nodes that can be found in chronically inflamed tissues in a number of inflammatory conditions. TLOs can host ongoing immune responses that can potentially contribute to disease pathogenesis.
Theresa T, Lu   +2 more
openaire   +2 more sources

P03.03 Organization, function and gene expression of tertiary lymphoid structures in PDAC resembles lymphoid follicles in secondary lymphoid organs [PDF]

open access: yesE-Poster Presentations, 2020
Background Secondary lymphoid organs (SLO) are involved in induction and enhancement of anti-tumor immune responses on different tumor entities. Recent evidence suggests that anti-tumor immune responses may also be induced or enhanced in the tumor microenvironment in so called tertiary lymphoid structures (TLS).
M Thelen   +14 more
openaire   +1 more source

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