Results 61 to 70 of about 9,564 (122)
Renal Interstitial Infiltration and Tertiary Lymphoid Organ Neogenesis in IgA Nephropathy [PDF]
Clinical Journal of the American Society of Nephrology, 2014 Previous studies have identified inflammatory features that enable the prediction of renal outcome of IgA nephropathy (IgAN); however, validation of these findings is still needed. This prospective study was performed to determine the characteristics of renal interstitial infiltration and tertiary lymphoid organ (TLO) neogenesis in a cohort of Chinese ...
Guangchang, Pei +11 more
openaire +2 more sources
Therapeutic use of dendritic cells to promote the extranodal priming of anti-tumor immunity
Frontiers in Immunology, 2013 Ectopic lymphoid tissue, also known as tertiary lymphoid organs (TLO) develop adaptively within sites of chronic tissue inflammation, thereby allowing the host to efficiently crossprime specific immune effector cells within sites of disease.
Lu eChen +3 more
doaj +1 more source
Biosynthesis and Functional Significance of Peripheral Node Addressin in Cancer-Associated TLO
Frontiers in Immunology, 2016 Peripheral node addressin (PNAd) marks high endothelial venules (HEV), which are crucial for the recruitment of lymphocytes into lymphoid organs in non-mucosal tissue sites.
Aliyah M. Weinstein, Walter J. Storkus
doaj +1 more source
BMC Immunology, 2020 Background Numerous data obtained by different research laboratories indicate that specific IgE production is triggered independently of specific IgG or IgA ones and so it is not linked to fully matured germinal centers formation in the secondary ...
Dmitrii Borisovich Chudakov +5 more
doaj +1 more source
T Follicular Helper-Like Cells in Inflamed Non-Lymphoid Tissues
Frontiers in Immunology, 2018 T and B cell cooperation normally takes place in secondary lymphoid organs (SLO). However, both cell types are also frequently found in inflamed non-lymphoid tissues.
Andreas Hutloff
doaj +1 more source
Epididymitis promotes formation of tertiary lymphoid organs in the cauda epididymidis
Mucosal ImmunologyUropathogenic Escherichia coli is a common pathogen that affects the cauda epididymidis, causing interstitial edema, epithelial damage, leukocyte infiltration, and fibrosis. Despite antibiotic treatment, up to 20 % of patients develop abscesses in the cauda epididymidis, and 40 % experience low sperm counts.
Hiba Hasan +17 more
openaire +2 more sources
Lymphoid stroma in all its states
Frontiers in ImmunologyStromal cells are found in all tissues of the body. Among them, lymphoid stromal cells (LSCs) correspond to the cell subsets found in secondary and tertiary lymphoid organs.
Nicolas Barbier +5 more
doaj +1 more source
Ectopic Lymphoid Structures: powerhouse of autoimmunity
Frontiers in Immunology, 2016 Ectopic lymphoid structures (ELS) often develop at sites of inflammation in target tissues of autoimmune diseases such as rheumatoid arthritis, Sjögren’s syndrome, multiple sclerosis, myasthenia gravis and systemic lupus erythematosus.
Elisa Corsiero +3 more
doaj +1 more source
Current Opinion in Immunology, 2019 Tertiary lymphoid organs named also tertiary lymphoid structures (TLS) often occur at sites of autoimmune inflammation, organ transplantation and cancer. Although the mechanisms for their formation/function are not entirely understood, it is known that TLS can display features of active germinal centres supporting the proliferation and differentiation ...
Elisa Corsiero +3 more
openaire +3 more sources
Somatic mutation-associated T follicular helper cell elevation in lung adenocarcinoma
OncoImmunology, 2018 T follicular helper cells (Tfh) play crucial roles in the development of humoral immunity. In the B cell-rich germinal center of lymphoid organs, they select for high-affinity B cells and aid in their maturation.
Kevin W Ng +7 more
doaj +1 more source