[Induction and Anti-Tumor Function of Tertiary Lymphoid Organs]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue Ban, 2022 To induce the development of tertiary lymphoid organs (TLO) in a mouse model of melanoma and to evaluate TLO's functions in antitumor immunity.Lymphotoxin-beta receptor (LTβR) was overexpressed in NIH3T3 cells through the lentivirus system and the overexpression efficiency of LTβR in LTβR-NIH3T3 cells was examined.
Chen H, Hu X, Zhang HY, Hu HB.
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Tertiary Lymphoid Organs Are Associated With Bacterial Dysbiosis in Chronic Rhinosinusitis. [PDF]
Int Forum Allergy RhinolISSN:2042 ...
Paramasivan S +9 more
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Tertiary lymphoid organs in recalcitrant chronic rhinosinusitis [PDF]
Journal of Allergy and Clinical Immunology, 2017 The letter to the editor. ; Abstract not available ; Aden Lau, Susan Lester, Sophia Moraitis, Judy Ou, Alkis J.
Lau, A. +8 more
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High endothelial venules and other blood vessels: critical regulators of lymphoid organ development and function [PDF]
, 2017 The blood vasculature regulates both the development and function of secondary lymphoid organs by providing a portal for entry of hemopoietic cells. During the development of lymphoid organs in the embryo, blood vessels deliver lymphoid tissue inducer ...
Ager, Elizabeth
core +4 more sources
Tertiary lymphoid organs in infection and autoimmunity. [PDF]
Trends Immunol, 2012 The lymph nodes (LNs) and spleen have an optimal structure that allows the interaction between T cells, B cells and antigen-presenting dendritic cells (DCs) on a matrix made up by stromal cells. Such a highly organized structure can also be formed in tertiary lymphoid organs (TLOs) at sites of infection or chronic immune stimulation.
Neyt K +4 more
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IL-17 initiates tertiary lymphoid organ formation [PDF]
Cellular & Molecular Immunology, 2011 Chronic inflammatory infiltrates that take on the form of organized lymphoid organs are called tertiary lymphoid organs (TLOs). The inflammatory cytokine interleukin-17 is now found to be the critical participant driving the development of a type of TLO called inducible bronchus-associated lymphoid tissue (iBALT) in an animal model of neonatal ...
Xueguang, Zhang, Binfeng, Lu
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Tertiary Lymphoid Structures and Cancer Prognosis (Brief Review)
Креативная хирургия и онкология, 2020 This brief review is devoted to the role of tertiary lymphoid structures in oncological processes. A number of research studies carried out over the past ten years have shed light on the functions of such structures in various diseases, as well as their ...
R. A. Rustamkhanov +2 more
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Identification of novel genes associated with renal tertiary lymphoid organ formation in aging mice. [PDF]
PLoS ONE, 2014 A hallmark of aging-related organ deterioration is a dysregulated immune response characterized by pathologic leukocyte infiltration of affected tissues. Mechanisms and genes involved are as yet unknown.
Yuan Huang +9 more
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Tertiary lymphoid structures and B lymphocytes in cancer prognosis and response to immunotherapies
OncoImmunology, 2021 Tertiary lymphoid structures (TLS) are ectopic cellular aggregates that resemble secondary lymphoid organs in their composition and structural organization.
Jacquelot N, Tellier J, Nutt Sl, Belz Gt
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IL-22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organs. [PDF]
Proc Natl Acad Sci U S A, 2015 Significance Ectopic clusters of immune cells that mimic the structure and function of secondary lymphoid organs are defined as tertiary lymphoid organs (TLOs). They have been observed at sites of chronic inflammation for decades, but their formation and function have remained enigmatic.
Barone F +17 more
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