Results 41 to 50 of about 21,644 (273)
Perivascular adipose tissue inflammation in vascular disease [PDF]
, 2017 Perivascular adipose tissue (PVAT) plays a critical role in the pathogenesis of cardiovascular disease. In vascular pathologies, perivascular adipose tissue increases in volume and becomes dysfunctional, with altered cellular composition and molecular ...
Guzik, Tomasz J., Nosalski, Ryszard
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Frontiers in Immunology, 2016 Tertiary lymphoid organs (TLOs) are frequently observed in tissues affected by non-resolving inflammation as a result of infection, autoimmunity, cancer and allograft rejection.
Gareth Wyn Jones +2 more
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B cells and tertiary lymphoid organs in renal inflammation [PDF]
Kidney International, 2008 B lymphocytes are part of the inflammatory cells recruited to the human kidney in various disease settings. B cell infiltrates have been described in renal allografts, in acute and chronic interstitial nephritis, and the most common glomerular diseases like immunoglobulin A (IgA) and membranous nephropathy.
Segerer, S., Schlöndorff, D.
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Chinese Journal of Lung Cancer, 2023 Lung cancer is the leading cause of cancer death, and non-small cell lung cancer (NSCLC) accounts for 85%. Immunotherapy has significantly improved the clinical prognosis of patients with NSCLC. However, because of the complexity and heterogeneousness of
Ying LIU +6 more
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Transplantation of embryonic spleen tissue reveals a role for adult non-lymphoid cells in initiating lymphoid tissue organization [PDF]
, 2009 In this report we describe a transplantation system where embryonic spleens are grafted into adult hosts. This model can be used to analyze the cellular and molecular requirements for the development and organization of splenic microenvironments.Whole ...
Aloisi +43 more
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Tertiary lymphoid structures are critical for cancer prognosis and therapeutic response
Frontiers in Immunology, 2023 Tertiary lymphoid structures (TLSs) are ectopic lymphocyte aggregates that form at sites of chronic inflammation, including cancers, in non-lymphoid tissues.
Qianqian Zhang, Suhui Wu
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Synthesis of artificial lymphoid tissue with immunological function. [PDF]
, 2010 The ability to generate functional artificial lymphoid tissue to induce specific immunity at ectopic sites could offer a potential breakthrough for treatment of diseases such as cancer and severe infection using immunotherapy.
Kobayashi, Yuka, Watanabe, Takeshi
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P03.03 Organization, function and gene expression of tertiary lymphoid structures in PDAC resembles lymphoid follicles in secondary lymphoid organs [PDF]
E-Poster Presentations, 2020 Background Secondary lymphoid organs (SLO) are involved in induction and enhancement of anti-tumor immune responses on different tumor entities. Recent evidence suggests that anti-tumor immune responses may also be induced or enhanced in the tumor microenvironment in so called tertiary lymphoid structures (TLS).
M Thelen +14 more
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Tertiary Lymphoid Structures: Autoimmunity Goes Local
Frontiers in Immunology, 2018 Tertiary lymphoid structures (TLS) are frequently observed in target organs of autoimmune diseases. TLS present features of secondary lymphoid organs such as segregated T and B cell zones, presence of follicular dendritic cell networks, high endothelial ...
Elena Pipi +6 more
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Targeting inflammation to reduce cardiovascular disease risk: a realistic clinical prospect? [PDF]
, 2017 Data from basic science experiments is overwhelmingly supportive of the causal role of immune-inflammatory response(s) at the core of atherosclerosis, and therefore the theoretical potential to manipulate the inflammatory response to prevent ...
Abbas +173 more
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