Results 51 to 60 of about 21,644 (273)

Bimodal Expansion of the Lymphatic Vessels Is Regulated by the Sequential Expression of IL-7 and Lymphotoxin α1β2 in Newly Formed Tertiary Lymphoid Structures. [PDF]

, 2016
Lymphangiogenesis associated with tertiary lymphoid structure (TLS) has been reported in numerous studies. However, the kinetics and dynamic changes occurring to the lymphatic vascular network during TLS development have not been studied.
Barone, F., Buckley, C.D., Caamaño, J.H., Campos, J., Chachlani, M., Chung, M.M., Cloake, T., Gardner, D.H., Luther, S., McGettrick, H.M., Navarro-Núñez, L., Nayar, S., Rankin, P., Steinthal, N., Watson, S.P.   +14 more
core   +2 more sources

Follicular dendritic cells, conduits, lymphatic vessels, and high endothelial venules in tertiary lymphoid organs: Parallels with lymph node stroma

Frontiers in Immunology, 2012
In this communication, the contribution of stromal, or non-hematopoietic, cells to the structure and function of lymph nodes (LNs), as canonical secondary lymphoid organs (SLOs), is compared to that of tertiary lymphoid tissue or organs (TLOs), also ...
Sharon eStranford, Nancy H. Ruddle
doaj   +1 more source

Class-switched anti-insulin antibodies originate from unconventional antigen presentation in multiple lymphoid sites [PDF]

, 2016
Autoantibodies to insulin are a harbinger of autoimmunity in type 1 diabetes in humans and in non-obese diabetic mice. To understand the genesis of these autoantibodies, we investigated the interactions of insulin-specific T and B lymphocytes using T ...
Acevedo-Suárez, Achenbach, Adelstein, Akashi, Batista, Bodansky, Cooke, Crotty, Dean, Emil R. Unanue, Ferris, Gagnerault, Garside, Gitlin, Glazier, Goodnow, Greeley, Gretz, Harbers, Henry, Henry, Henry-Bonami, Hoppu, Hu, Hulbert, Höglund, James W. Thomas, Kendall, Kendall, Kenefeck, Levisetti, Linterman, Mariño, Mohan, Mohan, Mohan, Nakayama, Noorchashm, Okada, Pape, Rasio, Reinhardt, Rojas, Roozendaal, Serreze, Silva, Takahashi, Ueno, Unanue, Victora, Victora, Vinuesa, Vomund, Williams, Xiaoxiao Wan, Yang, Zhang, Zhang, Zikherman, Zotos   +59 more
core   +2 more sources

Tertiary lymphoid structures in gynecological cancers: prognostic role, methods for evaluating, antitumor immunity, and induction for therapy

Frontiers in Oncology, 2023
Tertiary lymphoid structures (TLSs), referred to as tertiary lymphoid organs and lymphoid tissue neogenesis, are aggregates of immune cells that occur in nonlymphoid tissues.
Ke Zhang, Xiao Xie, Shuang-Lin Zheng, Yuan-Run Deng, Yuan-Run Deng, Dan Liao, Dan Liao, Hai-Chen Yan, Xi Kang, Hui-Ping Jiang, Hui-Ping Jiang, Sui-Qun Guo, Sui-Qun Guo   +12 more
doaj   +1 more source

Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease: the salivary glands of patients with Sjögren's syndrome [PDF]

, 1998
Structures resembling germinal centers are seen in the salivary glands of patients with Sjögren's syndrome, but it is not known whether the microenvironment of these cell clusters is sufficient for the induction of a germinal center response.
Berek, C., Hiepe, F., Hummel, M., Steinhauser, G., Stott, D.I.   +4 more
core   +2 more sources

New insights into the pathogenesis of giant cell arteritis [PDF]

, 2016
Giant cell arteritis (GCA) is an inflammatory chronic disease occurring exclusively in elderly individuals. Until recently, the disease has been considered a unique disease resulting from the interaction in the walls of susceptible arteries, between an ...
Francesco Ciccia, Aroldo Rizzo, Angelo Ferrante, Giuliana Guggino, Stefania Croci, Alberto Cavazza, Carlo Salvarani, Giovanni Triolo, Salvarani, Calamia, Hunder, Salehi-Abari, Genereau, Cavazza, Hernández-Rodríguez, Lie, Weyand, Weyand, Gabriel, Esteban, Restuccia, Wing, Petursdottir, Wagner, Giardina, Nagel, Nagel, Jones, Pisapia, Rhee, Carmona, Gonzalez-Gay, Weyand, Mackie, Carmona, González-Gay, Rauzy, Mackie, Lester, Carmona, Coit, Mattey, Gonzalez-Gay, Boiardi, Amoli, Salvarani, Márquez, Palomino-Morales, Rodríguez-Rodríguez, Márquez, Amoli, Makki, Salvarani, Boiardi, Gonzalez-Gay, Rodriguez-Pla, Alvarez-Rodriguez, Morgan, Salvarani, Carmona, Serrano, Alvarez-Rodríguez, Hu, Pitzalis, Ciccia, Amft, Litsiou, Álvarez Rodríguez, Ma-Krupa, Wagner, VandenEijnden, Netea, Shao, Kim, Nold-Petry, Ciccia, Hunter, Wong, Palmer, Ciccia, Weyand, DuPage, Deng, Weyand, Ciccia, Weyand, Espígol-Frigolé, Zhang, Said, Miyabe, Leavy, Banks, Cid, Martinez-Taboada, Samson, Wen, Schmits, Smith, Brack, Weyand, van der Geest, Alba, Foell, Nadkarni, Sibilano, Mäyränpää, Dimitrijevic, Cid, Régent, Croci, Kriegel   +110 more
core   +3 more sources

Hyperactive gp130/STAT3-driven gastric tumourigenesis promotes submucosal tertiary lymphoid structure development [PDF]

, 2018
Tertiary lymphoid structures (TLSs) display phenotypic and functional characteristics of secondary lymphoid organs, and often develop in tissues affected by chronic inflammation, as well as in certain inflammation-associated cancers where they are ...
Balic, Jesse J., Bhathal, Prithi S., D'Costa, Kimberley, Ferrero, Richard L., Gallimore, Awen M., Gao, Hugh, Hill, David, Jenkins, Brendan J., Jones, Gareth W., McLeod, Louise, Oshima, Hiroko, Oshima, Masanobu, Sievert, William, West, Alison, Yu, Liang   +14 more
core   +4 more sources

CD4 T lymphocyte autophagy is upregulated in the salivary glands of primary Sjögren’s syndrome patients and correlates with focus score and disease activity [PDF]

, 2017
Background: Primary Sjögren’s syndrome (pSS) is a common chronic autoimmune disease characterized by lymphocytic infiltration of exocrine glands and peripheral lymphocyte perturbation.
A Bhattacharya, AG Tzioufas, Annacarla Finucci, Antonina Minniti, Aroldo Rizzo, C Alessandri, C Li, C Vitali, C Vitali, CQ Nguyen, Cristiana Barbati, Cristiano Alessandri, D Geem, DJ Klionsky, DM Chisholm, E Astorri, Elena Ortona, Elisa Astorri, F Barone, F Ciccia, F Ciccia, F Ciccia, F Ciccia, F Sallusto, Fabrizio Conti, Francesco Ciccia, Giovanni Triolo, Giuliana Guggino, Guido Valesini, H Nakatogawa, HH Pua, HH Pua, HH Pua, I Tanida, LM Gerland, M Bombardieri, M Bombardieri, M Morgan-Bathke, M Morgan-Bathke, M Moriyama, M Pierdominici, Marina Pierdominici, Marta Vomero, Monica Pendolino, N Mizushima, N Schmitt, R Seror, Riccardo Alessandro, Roberta Priori, S Katsiougiannis, S Romao, Tania Colasanti, TC Adamson 3rd, W Jia, Walter Malorni, XJ Zhou, Y Seo, YZ Gong, Z Yang   +58 more
core   +3 more sources

Renal Interstitial Infiltration and Tertiary Lymphoid Organ Neogenesis in IgA Nephropathy [PDF]

Clinical Journal of the American Society of Nephrology, 2014
Previous studies have identified inflammatory features that enable the prediction of renal outcome of IgA nephropathy (IgAN); however, validation of these findings is still needed. This prospective study was performed to determine the characteristics of renal interstitial infiltration and tertiary lymphoid organ (TLO) neogenesis in a cohort of Chinese ...
Guangchang, Pei, Rui, Zeng, Min, Han, Panli, Liao, Xuan, Zhou, Yueqiang, Li, Ying, Zhang, Ping, Liu, Chunxiu, Zhang, XiaoCheng, Liu, Ying, Yao, Gang, Xu   +11 more
openaire   +2 more sources

Tertiary lymphoid structures and B lymphocytes: a promising therapeutic strategy to fight cancer

Frontiers in Immunology, 2023
Tertiary lymphoid structures (TLSs) are clusters of lymphoid cells with an organization that resembles that of secondary lymphoid organs. Both structures share common developmental characteristics, although TLSs usually appear in chronically inflamed non-
Laura Esparcia-Pinedo, Laura Esparcia-Pinedo, Nuria Romero-Laorden, Nuria Romero-Laorden, Arantzazu Alfranca, Arantzazu Alfranca, Arantzazu Alfranca, Arantzazu Alfranca   +7 more
doaj   +1 more source