Results 101 to 110 of about 11,902 (192)

A model of tertiary lymphatic structure-related prognosis for penile squamous cell carcinoma

BMC Urology
Background We investigated the feasibility of the tertiary lymphoid structure (TLS) as a prognostic marker for penile squamous cell carcinoma(SCC). Methods We retrospectively collected data from 83 patients with penile squamous cell carcinoma.
Han Tang, Zhengwei Su, Qingming Huang, Yongpeng Li, Rongchao Chen, Chengjie Ban, Chanzhen Liu, Haoyuan Lu, Xian-lin Yi, Yong Tang   +9 more
doaj   +1 more source

Chinese Expert Consensus on Assessment and Clinical Application of 
Tertiary Lymphoid Structure for Non-small Cell Lung Cancer (2025 Version)

Chinese Journal of Lung Cancer
The tertiary lymphoid structure (TLS) plays a crucial role in the tumor microenvironment, influencing tumor development and progression. As an emerging biomarker for predicting the prognosis and treatment response in cancer patients, TLS has received ...
Lung Cancer Collaboration Group of Tumor Pathology Committee of Chinese Anti-Cancer Association, Expert Committee on Non-small Cell Lung Cancer of Chinese Society of Clinical Oncology   +1 more
doaj   +1 more source

Tertiary lymphoid structures in high-grade serous tubo-ovarian carcinoma: anatomical site matters

Cancer Immunology, Immunotherapy
Tertiary lymphoid structures (TLS) in the tumor microenvironment are prognostically beneficial in many solid cancer types. Reports on TLS in high-grade serous tubo-ovarian carcinoma (HGSC) are few, and the prognostic impact is unclear.
Sofia Westbom-Fremer, Lena Tran, Anna Ebbesson, Laura Martin de la Fuente, Jenny-Maria Jönsson, Päivi Kannisto, Srinivas Veerla, Ingrid Hedenfalk   +7 more
doaj   +1 more source

The tertiary lymphoid structure-related signature identified PTGDS in regulating PD-L1 and promoting the proliferation and migration of glioblastoma

Background: Tertiary lymphoid structure (TLS) is a unique organ that carries out tumor cell elimination at tumor sites. It is continuously stimulated by inflammatory tumor signals and has been found to augment immunotherapy response.
Chi Zhang, Kun Liu, He Li, Ziyu Dai, Xisong Liang, Zeyu Wang, Peng Luo, Hao Zhang, Wantao Wu, Nan Zhang, Shuyu Li   +10 more
core   +1 more source

Quantifying Tertiary Lymphoid Structure-Associated Genes in Formalin-Fixed Paraffin-Embedded Breast Cancer Tissues.

, 2018
Tertiary lymphoid structures (TLS) have been detected in several types of human solid tumors. These structures are thought to regulate local adaptive immune responses that can promote or antagonize tumor progression.
Cinzia Solinas, Garaud, Soizic, Soizic Garaud, Chunyan Gu-Trantien, Solinas, Cinzia, Jean-Nicolas Lodewyckx, Willard-Gallo, Karen, Lodewyckx, Jean Nicolas, Karen Willard-Gallo, Edoardo Migliori, Gu-Trantien, Chunyan, Migliori, Edoardo   +11 more
core   +1 more source

The impact of tertiary lymphoid structure on the efficacy of postoperative adjuvant transcatheter arterial chemoembolization in patients with hepatocellular carcinoma

Zhongguo Linchuang Yixue
ObjectiveTo explore the impact of tertiary lymphoid structure (TLS) on the efficacy of adjuvant transcatheter arterial chemoembolization (TACE) following curative resection in patients with hepatocellular carcinoma (HCC).
Fansheng MENG, Haokang YANG, Biwei YANG
doaj   +1 more source

From Lymphotoxin to Tertiary Lymphoid Structures and Beyond

Immunological Reviews
ABSTRACT Lymphoid organ development occurs in ontogeny in the absence of antigenic stimulation; inflammation occurs after some immunological insult. These subjects had originally been considered as separate fields of research. Inflammation is due to inflammatory mediators such as lymphotoxin (LT) and its close relative, tumor necrosis
openaire   +2 more sources

Interplay between inflammation, autoimmunity and regeneration in the NOD mouse model of type 1 diabetes and Sjogren’s Syndrome.

, 2011
PhDA continuous process of tissue remodelling and regeneration is a fundamental feature of the homeostatic response of the target organ of several autoimmune diseases.
Astorri, Elisa
core  

Increased IgG4 expression within tertiary lymphoid structures of esophageal cancer and implications for prognosis

Frontiers in Immunology
BackgroundTertiary lymphoid structures (TLS) have been observed in various tumors, including esophageal squamous cell carcinoma (ESCC), where they function as active centers of humoral immunity within the tumor microenvironment, facilitating the ...
Chanjuan Su, Shuqi Chen, Xuqing He, Changchun Ma, Wei Huang, Chunyan Zhu, Hui Wang, Jiang Gu, Jiang Gu   +8 more
doaj   +1 more source

The Absence of Intra‐Tumoral Tertiary Lymphoid Structures is Associated with a Worse Prognosis and mTOR Signaling Activation in Hepatocellular Carcinoma with Liver Transplantation: A Multicenter Retrospective Study

Advanced Science
Tertiary lymphoid structure (TLS) can predict the prognosis and sensitivity of tumors to immune checkpoint inhibitors (ICIs) therapy, whether it can be noninvasively predicted by radiomics in hepatocellular carcinoma with liver transplantation (HCC‐LT ...
Jianhua Li, Li Zhang, Hao Xing, Yan Geng, Shaocheng Lv, Xiao Luo, Weiqiao He, Zhi Fu, Guangming Li, Bin Hu, Shengran Jiang, Zhe Yang, Ningqi Zhu, Quanbao Zhang, Jing Zhao, Yifeng Tao, Conghuan Shen, Ruidong Li, Feng Tang, Shusen Zheng, Yun Bao, Qiang He, Daoying Geng, Zhengxin Wang   +23 more
doaj   +1 more source