Results 91 to 100 of about 11,902 (192)

C‐Reactive Protein to Lymphocyte Ratio (CLR) and Lactate Dehydrogenase to Albumin Ratio (LAR) as Prognostic Biomarkers in Acral Melanoma: Association With Tertiary Lymphoid Structures and Immune Cell Infiltration

Cancer Medicine
Objective To investigate the correlation between peripheral blood CRP‐to‐lymphocyte ratio (CLR) and lactate dehydrogenase‐to‐albumin ratio (LAR) levels, prognosis, and the tumor microenvironment (TME) in patients with acral melanoma (AM), with a focus on
Donglin Kang, Xinyu Su, Jiayu Wang, Lianjun Zhao, Rong Huang, Zhengyun Zou   +5 more
doaj   +1 more source

The pivotal role of tertiary lymphoid structures in the tumor immune microenvironment

Frontiers in Oncology
Tertiary lymphoid structures (TLS) are ectopic lymphoid structures that form in non-lymphoid tissues in response to chronic inflammatory stimulation. Structurally and functionally resembling lymph nodes, TLS are primarily composed of B cells, T cells ...
Chengsen Liu, Jiandong Cao
doaj   +1 more source

Multi-omics profiling and experimental verification of tertiary lymphoid structure-related genes: molecular subgroups, immune infiltration, and prognostic implications in lung adenocarcinoma [PDF]

Lung adenocarcinoma (LUAD), characterized by a low 5-year survival rate, is the most common and aggressive type of lung cancer. Recent studies have shown that tertiary lymphoid structures (TLS), which resemble lymphoid structures, are closely linked to ...
Sixuan Wu, Qihong Pan, Lijun Zeng, Yuehua Li, Junfan Pan, Renji Liang   +5 more
core   +1 more source

Tertiary lymphoid organs in wild boar exposed to a low-virulent isolate of African swine fever virus

Authors’ contributions: NPG, ARB, JMSV and JAB designed the study. NPG, ARB, AK and JAB performed the sampling and veterinary inspection. NPG and AK performed laboratory analysis. ARB and JMSV acquired the funds. NPG wrote the initial manuscript.
Porras González, Néstor, Antonio Rodríguez-Bertos, Aleksandra Kosowska, Kosowska, Aleksandra, José Á. Barasona, Barasona García-Arévalo, José Ángel, Rodríguez Bertos, Antonio Manuel, Sánchez-Vizcaíno Rodríguez, José Manuel, Néstor Porras, José M. Sánchez-Vizcaíno   +9 more
core   +1 more source

Association of IL-36γ with tertiary lymphoid structures and inflammatory immune infiltrates in human colorectal cancer

, 2019
International audienceIL-1 family cytokines play a dual role in the gut, with different family members contributing either protective or pathogenic effects. IL-36γ is an IL-1 family cytokine involved in polarizing type-1 immune responses.
Fridman, Wolf H, Storkus, Walter J, Emile, Jean-François, Lacroix, Laetitia, Sautès-Fridman, Catherine, Weinstein, Aliyah M, Petitprez, Florent, Giraldo, Nicolas A, Peschaud, Frédérique, Julie, Catherine, Marisa, Laetitia   +10 more
core   +1 more source

Artery tertiary lymphoid organs control aorta immunity and protect against atherosclerosis via vascular smooth muscle cell lymphotoxin β receptors [PDF]

, 2015
Tertiary lymphoid organs (TLOs) emerge during nonresolving peripheral inflammation, but their impact on disease progression remains unknown. We have found in aged Apoe−/− mice that artery TLOs (ATLOs) controlled highly territorialized aorta T cell ...
Grabner, Rolf, MacRitchie, Neil, Burton, F.L., Beer, Michael, S.a.r.a.j.o. .K. Mohanta, Weih, Falk, Dever, Gary, Michael Beer, A.n.d.r.e.a.s. .J. R. Habenicht, Weber, Christian, Sabir, Suleman R., Livia Habenicht, J.a.m.e.s. .M. Brewer, Burton, Francis L., Changjun Yin, MacRitchie, N., Desheng Hu, Habenicht, Andreas J. R., Sabir, S.R., Habenicht, L., Mohanta, S.K., Yin, C., Gordon, Peter, Srikakulapu, Prasad, Daniel Teupser, Gary Dever, Mohanta, Sarajo K., Lehmann, T., Hu, Desheng, Peng, Li, Habenicht, A.J.R., Maffia, Pasquale, Lehmann, Thomas, F.r.a.n.c.i.s. .L. Burton, Teupser, D., Peter Gordon, S.u.l.e.m.a.n. .R. Sabir, Gordon, P.M., Ialenti, Armando, Paul Garside, Dever, G., Habenicht, Livia, Peng, L., Maffia, P., Weber, C., Beer, M., Grassia, G., McInnes, Iain B., Grabner, R., Li Peng, Habenicht, Andreas J.R., McInnes, I.B., Zhe Ma, Neil MacRitchie, Prasad Srikakulapu, I.a.i.n. .B. McInnes, Hu, D., Brewer, James M., Ma, Z., Brewer, J.M., Ma, Zhe, Ialenti, A., Habenicht, Andreas J R, Srikakulapu, P., Grassia, Gianluca, Yin, Changjun, Rolf Grabner, Falk Weih, Thomas Lehmann, Garside, P., Garside, Paul, Teupser, Daniel, Christian Weber, Weih, F.   +73 more
core   +1 more source

Lymphoid like stromal cells in a model of tertiary lymphoid organ formation

, 2014
Tertiary lymphoid organs (TLOs) are a hallmark of many chronic immune-mediated inflammatory diseases. However, till date the series of events leading to stromal cell activation in TLOs and their role in the inflammatory process remain unclear.
Nayar, Saba
core  

Follicular dendritic cells, conduits, lymphatic vessels, and high endothelial venules in tertiary lymphoid organs: Parallels with lymph node stroma

, 2012
In this communication, the contribution of stromal, or non-hematopoietic, cells to the structure and function of lymph nodes (LNs), as canonical secondary lymphoid organs (SLOs), is compared to that of tertiary lymphoid tissue or organs (TLOs), also ...
Sharon Stranford, Nancy H. Ruddle, Sharon eStranford   +2 more
core   +1 more source

Lymphoid stroma in all its states

Frontiers in Immunology
Stromal cells are found in all tissues of the body. Among them, lymphoid stromal cells (LSCs) correspond to the cell subsets found in secondary and tertiary lymphoid organs.
Nicolas Barbier, Nicolas Barbier, Valentin Isen, Karin Tarte, Karin Tarte, David Roulois   +5 more
doaj   +1 more source

Tertiary Lymphoid Structures in Microorganism-Related Cancer

Cancers
Tertiary lymphoid structures (TLSs) are ectopic lymphoid tissues formed by the accumulation of lymphocytes and other components outside lymphoid organs. They have been shown to be widespread in cancers and have predictive effects on prognosis and immunotherapy efficacy; however, there is no standardized measurement guide.
Shuzhe Deng, Xinxin Yang, Lin He, Yunjing Hou, Hongxue Meng   +4 more
openaire   +2 more sources