Results 21 to 30 of about 2,945 (208)
Characterizing tertiary lymphoid structures associated single-cell atlas in breast cancer patients
Cancer Cell InternationalThe tertiary lymphoid structure (TLS) is recognized as a potential prognosis factor for breast cancer and is strongly associated with response to immunotherapy.
Xiaokai Fan +9 more
doaj +2 more sources
The impact of tertiary lymphoid structure on the efficacy of postoperative adjuvant transcatheter arterial chemoembolization in patients with hepatocellular carcinoma [PDF]
Zhongguo Linchuang YixueObjectiveTo explore the impact of tertiary lymphoid structure (TLS) on the efficacy of adjuvant transcatheter arterial chemoembolization (TACE) following curative resection in patients with hepatocellular carcinoma (HCC).
Fansheng MENG, Haokang YANG, Biwei YANG
doaj +2 more sources
Editorial: Tertiary lymphoid structures (TLS) in the tumor immune microenvironment
Frontiers in ImmunologyXinbo Gao +5 more
exaly +4 more sources
Turning Tertiary Lymphoid Structures (TLS) into Hot Spots: Values of TLS in Gastrointestinal Tumors
Cancers, 2023 Tertiary lymphoid structures (TLSs) are ectopic lymphocyte aggregation structures found in the tumor microenvironment (TME). Emerging evidence shows that TLSs are significantly correlated with the progression of gastrointestinal tumors, patients’ prognosis, and the efficacy of adjuvant therapy. Besides, there are still some immunosuppressive factors in
Daming Cai +7 more
openaire +2 more sources
Stromal cells in tertiary lymphoid structures: Architects of autoimmunity [PDF]
, 2021 The molecular mediators present within the inflammatory microenvironment are able, in certain conditions, to favor the initiation of tertiary lymphoid structure (TLS) development.
Asam, Saba +8 more
core +1 more source
Frontiers in Immunology, 2023 Persistent inflammation can promote the development of tertiary lymphoid structures (TLS) within tissues resembling secondary lymphoid organs (SLO) such as lymph nodes (LN).
Marion Le Rochais +10 more
doaj +1 more source
Chinese Journal of Lung Cancer, 2023 Lung cancer is the leading cause of cancer death, and non-small cell lung cancer (NSCLC) accounts for 85%. Immunotherapy has significantly improved the clinical prognosis of patients with NSCLC. However, because of the complexity and heterogeneousness of
Ying LIU +6 more
doaj +1 more source
Frontiers in Immunology, 2021 Tertiary lymphoid structures (TLS) are ectopically formed aggregates of organized lymphocytes and antigen-presenting cells that occur in solid tissues as part of a chronic inflammation response.
Shota Aoyama +4 more
doaj +1 more source
PLOS ONE, 2021 Tertiary lymphoid structures (TLS) are ectopic aggregates of lymphoid cells in inflamed, infected, or tumoral tissues that are easily recognized on an H&E histology slide as discrete entities, distinct from lymphocytes. TLS are associated with improved cancer prognosis but there is no standardised method available to quantify their presence ...
Panagiotis Barmpoutis +6 more
openaire +5 more sources
Cutaneous Melanoma: Mutational Status and Potential Links to Tertiary Lymphoid Structure Formation
Frontiers in Immunology, 2021 Recent advances in immunotherapy have enabled rapid evolution of novel interventional approaches designed to reinvigorate and expand patient immune responses against cancer.
Deepak Salem +6 more
doaj +1 more source