Results 21 to 30 of about 3,198 (184)
LLT1-CD161 Interaction in Cancer: Promises and Challenges
Frontiers in Immunology, 2022 The success of immune checkpoint therapy in cancer has changed our way of thinking, promoting the design of future cancer treatments that places the immune system at the center stage.
Veronique M. Braud +5 more
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Frontiers in Immunology, 2022 BackgroundEpstein-Barr virus-associated gastric cancer (EBVaGC) exhibits unique histological characteristics within the immune-cell-rich microenvironment, but the role of tertiary lymphoid structure (TLS) in EBVaGC is not yet fully understood.MethodsWe ...
Yi-Xin Yin +24 more
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Role of Tertiary Lymphoid Structures (TLS) in Anti-Tumor Immunity: Potential Tumor-Induced Cytokines/Chemokines that Regulate TLS Formation in Epithelial-Derived Cancers [PDF]
Cancers, 2014 Following the successes of monoclonal antibody immunotherapies (trastuzumab (Herceptin®) and rituximab (Rituxan®)) and the first approved cancer vaccine, Provenge® (sipuleucel-T), investigations into the immune system and how it can be modified by a tumor has become an exciting and promising new field of cancer research.
Pimenta, Erica M., Barnes, Betsy J.
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Cellular and Molecular Gastroenterology and Hepatology, 2021 Background and aims: The presence of tertiary lymphoid structures (TLSs) may confer survival benefit to patients with pancreatic ductal adenocarcinoma (PDAC), in an otherwise immunologically inert malignancy.
Francesca R. Delvecchio +10 more
doaj +1 more source
Prognostic and therapeutic potential of gene profiles related to tertiary lymphoid structures in colorectal cancer [PDF]
PeerJThe role of tertiary lymphoid structures (TLS) in oncology is gaining interest, particularly in colorectal carcinoma, yet a thorough analysis remains elusive.
Jinglu Yu +3 more
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Frontiers in Immunology, 2021 Acquired immunity is orchestrated in various lymphoid organs, including bone marrow, thymus, spleen, and lymph nodes in humans. However, mucosa-associated lymphoid tissue (MALT) is evolutionally known to be emerged in the oldest vertebrates as an ...
Toshiaki Kogame +2 more
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Frontiers in Immunology, 2022 Tertiary lymphoid structure (TLS) and tumor-resident memory T cells (TRM) play crucial roles in the anti-tumor immune response, facilitating a good prognosis in patients with cancer. However, there have been no reports on the relationship between TRM and
Hua Zhao +25 more
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, 2023 Additional file 1: Supplementary Materials. Table S1. Quality assessment details for included studies. Table S2. Summary of controlled covariates in multivariate analyses. Figure S1. Sensitivity analysis for TLS with OS in digestive system cancers patients. Figure S2.
Sun, Hao +9 more
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Tertiary lymphoid structures in head and neck squamous cell carcinoma
Translational OncologyHead and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide. Smoking, drinking, and human papillomavirus (HPV) infection are the main risk factors.
Jing Zhu +4 more
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Tertiary lymphoid structures in cancer: maturation and induction
Frontiers in ImmunologyTertiary lymphoid structure (TLS) is an ectopic lymphocyte aggregate formed in peripheral non-lymphoid tissues, including inflamed or cancerous tissue.
Yulu Chen +11 more
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