Results 41 to 50 of about 29,370 (346)

A CT-based radiomics approach to predict intra-tumoral tertiary lymphoid structures and recurrence of intrahepatic cholangiocarcinoma

Insights into Imaging, 2023
Purpose To predict the tertiary lymphoid structures (TLSs) status and recurrence-free survival (RFS) of intrahepatic cholangiocarcinoma (ICC) patients using preoperative CT radiomics.
Ying Xu, Zhuo Li, Yi Yang, Lu Li, Yanzhao Zhou, Jingzhong Ouyang, Zhen Huang, Sicong Wang, Lizhi Xie, Feng Ye, Jinxue Zhou, Jianming Ying, Hong Zhao, Xinming Zhao   +13 more
doaj   +1 more source

Hyperactive gp130/STAT3-driven gastric tumourigenesis promotes submucosal tertiary lymphoid structure development [PDF]

, 2018
Tertiary lymphoid structures (TLSs) display phenotypic and functional characteristics of secondary lymphoid organs, and often develop in tissues affected by chronic inflammation, as well as in certain inflammation-associated cancers where they are ...
Balic, Jesse J., Bhathal, Prithi S., D'Costa, Kimberley, Ferrero, Richard L., Gallimore, Awen M., Gao, Hugh, Hill, David, Jenkins, Brendan J., Jones, Gareth W., McLeod, Louise, Oshima, Hiroko, Oshima, Masanobu, Sievert, William, West, Alison, Yu, Liang   +14 more
core   +4 more sources

Characteristics of tertiary lymphoid structures in primary cancers [PDF]

OncoImmunology, 2013
Tumors are sustained by complex networks of interactions between malignant cells, stromal cells and tumor-infiltrating immune cells. These networks differ from patient to patient in terms of nature, composition and organization as well as with regard to the precise localization of tumor-infiltrating cells.
Goc, Jérémy, Fridman, Wolf-Herman, Sautès-Fridman, Catherine, Dieu-Nosjean, Marie-Caroline   +3 more
openaire   +2 more sources

Transplantation of embryonic spleen tissue reveals a role for adult non-lymphoid cells in initiating lymphoid tissue organization [PDF]

, 2009
In this report we describe a transplantation system where embryonic spleens are grafted into adult hosts. This model can be used to analyze the cellular and molecular requirements for the development and organization of splenic microenvironments.Whole ...
Aloisi, Bajenoff, Bekiaris, Bekiaris, Brendolan, Chen, Cupedo, Cupedo, Cupedo, Drayton, Eberl, Fan, Fu, Fu, Futterer, Honda, Kim, Kim, Kim, Kim, Kim, Kratz, Link, Luther, Luther, Luther, Mackay, Mebius, Meier, Ngo, Ngo, Nolte, Rennert, Rossi, Scandella, Sun, Togni, Veiga-Fernandes, Vondenhoff, Wang, White, Withers, Yokota, Yoshida   +43 more
core   +2 more sources

Synthesis of artificial lymphoid tissue with immunological function. [PDF]

, 2010
The ability to generate functional artificial lymphoid tissue to induce specific immunity at ectopic sites could offer a potential breakthrough for treatment of diseases such as cancer and severe infection using immunotherapy.
Kobayashi, Yuka, Watanabe, Takeshi
core   +1 more source

Tertiary Lymphoid Structures in the Central Nervous System: Implications for Glioblastoma

Frontiers in Immunology, 2021
Glioblastoma is the most common and aggressive brain tumor, which is uniformly lethal due to its extreme invasiveness and the absence of curative therapies.
Tiarne van de Walle, Alessandra Vaccaro, Mohanraj Ramachandran, Ilkka Pietilä, Magnus Essand, Anna Dimberg   +5 more
doaj   +1 more source

Tertiary lymphoid structures in endometriosis

F&S Science
To determine whether tertiary lymphoid structures (TLSs), which reflect organized immune cell aggregates present in non-lymphoid tissues, are consistent features of endometriosis lesions.Detailed histopathological analysis of endometrial and lesion tissue from patients with endometriosis and controls was performed.
Katherine B. Zutautas, Priyanka Yolmo, Minqi Xu, Timothy Childs, Madhuri Koti, Chandrakant Tayade   +5 more
openaire   +2 more sources

Lymphotoxin signalling in tertiary lymphoid structures and immunotherapy [PDF]

Cellular & Molecular Immunology, 2017
Tertiary lymphoid structures (TLS) often develop at sites of persistent inflammation, including cancers and autoimmune diseases. In most cases, the presence of TLS correlates with active immune responses. Because of their proximity to pathological loci, TLS are an intriguing target for the manipulation of immune responses.
Haidong, Tang, Mingzhao, Zhu, Jian, Qiao, Yang-Xin, Fu   +3 more
openaire   +2 more sources

Using immunovascular characteristics to predict very early recurrence and prognosis of resectable intrahepatic cholangiocarcinoma

BMC Cancer, 2023
Objective To predict the very early recurrence (VER) of patients with intrahepatic cholangiocarcinoma (ICC) based on TLSs and MVI status, and further perform prognosis stratifications. Methods A total of 160, 51 ICC patients from two institutions between
Ying Xu, Zhuo Li, Yanzhao Zhou, Yi Yang, Jingzhong Ouyang, Lu Li, Zhen Huang, Feng Ye, Jianming Ying, Hong Zhao, Jinxue Zhou, Xinming Zhao   +11 more
doaj   +1 more source

Tertiary lymphoid structures and B lymphocytes: a promising therapeutic strategy to fight cancer

Frontiers in Immunology, 2023
Tertiary lymphoid structures (TLSs) are clusters of lymphoid cells with an organization that resembles that of secondary lymphoid organs. Both structures share common developmental characteristics, although TLSs usually appear in chronically inflamed non-
Laura Esparcia-Pinedo, Laura Esparcia-Pinedo, Nuria Romero-Laorden, Nuria Romero-Laorden, Arantzazu Alfranca, Arantzazu Alfranca, Arantzazu Alfranca, Arantzazu Alfranca   +7 more
doaj   +1 more source