Results 21 to 30 of about 13,664 (142)

Tertiary lymphoid structures in ovarian cancer

Frontiers in Immunology
Ovarian cancer (OC) is a significant cause of cancer-related mortality in women worldwide. Despite advances in treatment modalities, including surgery and chemotherapy, the overall prognosis for OC patients remains poor, particularly for patients with ...
Guojuan Sun, Yi Liu
doaj   +3 more sources

Tertiary lymphoid structures and their association to immune phenotypes and circulatory IL2 levels in pancreatic ductal adenocarcinoma

OncoImmunology, 2022
Pancreatic ductal adenocarcinoma (PDA) is usually unresponsive to immunotherapeutic approaches. However, tertiary lymphoid structures (TLS) are associated with favorable patient outcomes in PDA.
Azaz Ahmed, Sophia Köhler, Rosa Klotz, Nathalia Giese, Thilo Hackert, Christoph Springfeld, Inka Zörnig, Dirk Jäger, Niels Halama   +8 more
doaj   +2 more sources

Tertiary lymphoid structures and B lymphocytes in cancer prognosis and response to immunotherapies

OncoImmunology, 2021
Tertiary lymphoid structures (TLS) are ectopic cellular aggregates that resemble secondary lymphoid organs in their composition and structural organization.
Jacquelot N, Tellier J, Nutt Sl, Belz Gt
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Tertiary lymphoid structures in genitourinary cancers: a comprehensive review [PDF]

Frontiers in Oncology
Tertiary lymphoid structures (TLSs) are lymphoid cell clusters that form in non-lymphoid tissues in response to chronic inflammation and function as sites for localized, antigen-specific immune responses, potentially enhancing anti-tumor immunity.
Alvaro Abreu, Alejandra Viera Plasencia, Mercy Iribarren, Carter Wegner, Joana Nuraj, Elai Davicioni, Hisham F. Bahmad, Mohammed Shahait   +7 more
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Tertiary lymphoid structures in the era of cancer therapy [PDF]

Journal of Experimental & Clinical Cancer Research
On September 9th, 2025, the 3rd Workshop on Tertiary lymphoid structures (TLS) took place in Utrecht as pre-meeting to CICON2025. Advances in TLS biology, diversity, and clinical significance are rapidly reshaping the field.
Isaias Hernández-Verdin, Anna Dimberg, Daniela S. Thommen, Camilla Engblom, Lucile Vanhersecke, Karina Silina, Tullia C. Bruno, Wolf H. Fridman, Paola Nisticò, Catherine Sautès-Fridman   +9 more
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Tertiary lymphoid structures and B lymphocytes: a promising therapeutic strategy to fight cancer

Frontiers in Immunology, 2023
Tertiary lymphoid structures (TLSs) are clusters of lymphoid cells with an organization that resembles that of secondary lymphoid organs. Both structures share common developmental characteristics, although TLSs usually appear in chronically inflamed non-
Laura Esparcia-Pinedo, Laura Esparcia-Pinedo, Nuria Romero-Laorden, Nuria Romero-Laorden, Arantzazu Alfranca, Arantzazu Alfranca, Arantzazu Alfranca, Arantzazu Alfranca   +7 more
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The role of dendritic cells in tertiary lymphoid structures: implications in cancer and autoimmune diseases

Frontiers in Immunology
Tertiary Lymphoid Structures (TLS) are organized aggregates of immune cells such as T cells, B cells, and Dendritic Cells (DCs), as well as fibroblasts, formed postnatally in response to signals from cytokines and chemokines.
Mariana Reste, Kristi Ajazi, Ayca Sayi-Yazgan, Ayca Sayi-Yazgan, Radmila Jankovic, Biljana Bufan, Sven Brandau, Espen S. Bækkevold, Florent Petitprez, Malin Lindstedt, Gosse J. Adema, Catarina R. Almeida   +11 more
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Tertiary lymphoid structures in cancer: maturation and induction

Frontiers in Immunology
Tertiary lymphoid structure (TLS) is an ectopic lymphocyte aggregate formed in peripheral non-lymphoid tissues, including inflamed or cancerous tissue.
Yulu Chen, Yulu Chen, Yulu Chen, Yuhao Wu, Yuhao Wu, Yuhao Wu, Guorong Yan, Guorong Yan, Guorong Yan, Guolong Zhang, Guolong Zhang, Guolong Zhang   +11 more
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Newly formated (tertiary) lymphoid structures in tumor growth [PDF]

Наука и инновации в медицине, 2022
Aim to reproduce tertiary lymphoid structures and study their features in a malignant neoplasm in the experiment. Material and methods. Male white rats of the Wistar stress-resistant line were inoculated with the tumor strain sarcoma M1.
Rasul A. Rustamkhanov, Shamil R. Kzyrgalin, Dauranbek T. Arybzhanov, Kamil Sh. Gantsev, Davlat S. Tursumetov, Shamil Kh. Gantsev   +5 more
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Tertiary Lymphoid Structures and Cancer Prognosis (Brief Review)

Креативная хирургия и онкология, 2020
This brief review is devoted to the role of tertiary lymphoid structures in oncological processes. A number of research studies carried out over the past ten years have shed light on the functions of such structures in various diseases, as well as their ...
R. A. Rustamkhanov, K. Sh. Gantsev, D. S. Tursumetov   +2 more
doaj   +1 more source