Results 11 to 20 of about 13,821 (239)
Of mice and lymphoid aggregates: modeling tertiary lymphoid structures in cancer
Frontiers in Immunology, 2023 Tertiary lymphoid structures (TLS) are lymph node-like aggregates that can form in association with chronic inflammation or cancer. Mature TLS are organized into B and T cell zones, and are not encapsulated but include all cell types necessary for ...
Alessandra Vaccaro +4 more
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Tertiary lymphoid structures: The touchstone for tumor immunotherapy [PDF]
Acta Pharmaceutica Sinica BLisha Zhou, Shunji Liu, Yang Sun
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Tertiary lymphoid structures in colorectal cancer
Annals of MedicineBackground Tertiary lymphoid structures (TLS) are ectopic clusters of immune cells found in non-lymphoid tissues, particularly within the tumor microenvironment (TME).
Jianyu Lv +5 more
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Tertiary lymphoid structures in ovarian cancer
Frontiers in ImmunologyOvarian cancer (OC) is a significant cause of cancer-related mortality in women worldwide. Despite advances in treatment modalities, including surgery and chemotherapy, the overall prognosis for OC patients remains poor, particularly for patients with ...
Guojuan Sun, Yi Liu
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Frontiers in Immunology, 2017 Secondary lymphoid organs are integral to initiation and execution of adaptive immune responses. These organs provide a setting for interactions between antigen-specific lymphocytes and antigen-presenting cells recruited from local infected or inflamed ...
Emily Jayne Colbeck +3 more
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The formation and function of tertiary lymphoid structures
Biomarker ResearchTertiary lymphoid structures (TLSs) are immune cell aggregates that emerge in nonlymphoid tissues during various disease states, including chronic inflammation, autoimmunity, and cancer.
Chengzhang Zhang +7 more
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The Sunrise of Tertiary Lymphoid Structures in Cancer. [PDF]
Immunol RevABSTRACTFirst considered as a negative epiphenomenon in autoimmune and inflammatory diseases, with possible deleterious consequences through the production of pathological autoantibodies and antiself T cells, tertiary lymphoid structures (TLS) have gained major scientific and clinical interest in cancer due to their association with better clinical ...
Rochefort J +3 more
europepmc +3 more sources
Newly formated (tertiary) lymphoid structures in tumor growth [PDF]
Наука и инновации в медицине, 2022 Aim to reproduce tertiary lymphoid structures and study their features in a malignant neoplasm in the experiment. Material and methods. Male white rats of the Wistar stress-resistant line were inoculated with the tumor strain sarcoma M1.
Rasul A. Rustamkhanov +5 more
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Tertiary Lymphoid Structures and Cancer Prognosis (Brief Review)
Креативная хирургия и онкология, 2020 This brief review is devoted to the role of tertiary lymphoid structures in oncological processes. A number of research studies carried out over the past ten years have shed light on the functions of such structures in various diseases, as well as their ...
R. A. Rustamkhanov +2 more
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Does TLS Exist in Canine Mammary Gland Tumours? Preliminary Results in Simple Carcinomas
Veterinary Sciences, 2022 Neoplastic progression is influenced by the expression of tumour antigens that activate an anti-tumour immune response. Human medical studies show that this body defence is carried out in secondary lymphoid organs (SLOs) but also directly in the tumour ...
Giada Giambrone +7 more
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