Results 181 to 190 of about 5,610 (204)

702 Tertiary lymphoid structures (TLS) observed in non-small cell lung cancer (NSCLC) tumors treated with pulsed electric fields

Regular and Young Investigator Award Abstracts, 2022
Jeff Iding, Paul VanderLaan, Marcelo Jimenez, José Fernández García-Hierro, Javier Flandes Aldeyturriaga, Erik HFM van der Heijden, Calvin SH Ng, Rainbow WH Lau, Maria Ludeña, Rafael Carías, Oderay Cedeño, Alicia Moreno-Gonzalez, Beryl Hatton, William Krimsky   +13 more
openaire   +1 more source

Abstract 3205: Artificial intelligence (AI) -powered H&E whole-slide image (WSI) analysis of tertiary lymphoid structure(TLS) to predict response to immunotherapy in non-small cell lung cancer (NSCLC)

Cancer Research
Background: The efficacy of ICIs in treating NSCLC is limited to a subset of patients, necessitating reliable predictive biomarkers. TLSs within the tumor microenvironment have emerged as potential indicators. This study aims to investigate the association between an AI-powered TLS analysis and treatment response of
Young Kwang Chae, Leeseul Kim, Sangwon Shin, Sooick Cho, Sanghoon Song, Borislav Alexiev, Behtash Nezami   +6 more
openaire   +1 more source

SO016/#846  Deep learning for spatial distribution of tertiary lymphoid structures (TLS) and efficacy of immunotherapy for endometrial cancer

Closing Session: the Development of Prognosis and Predictive Markers, 2023
Junzo Hamanishi, Haruka Suzuki, Akihiko Ueda, Ken Yamaguchi, Masaki Mandai   +4 more
openaire   +1 more source

5P Tertiary lymphoid structures (TLS) presence and stromal blood vessels heterogeneity differentially influence recurrence, lymphovascular, and perineural invasion in breast cancer molecular subtypes

Annals of Oncology, 2023
A.A. Cosma, A.C. Barb, S.M. Negru, M.M. Pasca Fenesan, A.M. Cimpean   +4 more
openaire   +1 more source

B cells and tertiary lymphoid structures as determinants of tumour immune contexture and clinical outcome

Nature Reviews Clinical Oncology, 2022
Wolf H Fridman, Maxime Meylan, Florent Petitprez   +2 more
exaly  

Tertiary lymphoid structures in cancer

Science, 2022
Ton N M Schumacher, Daniela S Thommen
exaly  

TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures

Immunity, 2022
Ricardo A Chaurio, Carmen M Anadon, Tara Lee Costich   +2 more
exaly  

Tertiary lymphoid structures and B cells: An intratumoral immunity cycle

Immunity, 2023
Wolf H Fridman, Maxime Meylan
exaly  

Tu1428 ELUCIDATION OF TUMOR IMMUNE SYSTEM MEDIATED BY TLS (TERTIARY LYMPHOID STRUCTURE) IN PANCREATIC CANCER

Gastroenterology
Takeshi Tanaka, Atsuhiro Masuda, Yuzo Kodama   +2 more
openaire   +1 more source

Tertiary lymphoid structures generate and propagate anti-tumor antibody-producing plasma cells in renal cell cancer

Immunity, 2022
Maxime Meylan, Florent Petitprez, Guilhem Pupier   +2 more
exaly