Results 31 to 40 of about 5,610 (204)
Tertiary Lymphoid Structures in Cancer: Drivers of Antitumor immunity, immunosuppression, or Bystander Sentinels in Disease? [PDF]
, 2017 Secondary lymphoid organs are integral to initiation and execution of adaptive immune
responses. These organs provide a setting for interactions between antigen-specific
lymphocytes and antigen-presenting cells recruited from local infected or ...
Adachi, Ager, Ager, Aloisi, Andrian von, Ansel, Attridge, Avram, Banks, Bell, Bento, Bergomas, Bombardieri, Browning, Buckley, Bénézech, Calcinotto, Carragher, Carrega, Cañete, Chai, Chen, Cipponi, Colbeck, Coles, Contractor, Coppola, Coronella, de Chaisemartin, De Togni, Deteix, Di Caro, Dieu-Nosjean, Dieu-Nosjean, Drayton, Drayton, Eberl, Fan, Fava, Figenschau, Finkin, Foo, Furman, Furtado, Furtado, Förster, Galkina, Gallimore, Gantsev, García-Hernández, Gardner, Gatumu, Germain, Giraldo, Girard, Gobert, Goc, Goc, Gopal, Gräbner, Gu-Trantien, Hamanishi, Hindley, Hiraoka, Hjelmström, Johansson-Percival, Jones, Joshi, Joyce, Katakai, Kirk, Klages, Kocks, Kratz, Kroeger, Ladányi, Lee, Li, Liao, Lochner, Low, Lu, Luther, Luther, Luther, Marinkovic, Martinet, Martinet, Martinet, McMahon, McMullen, Mebius, Mebius, Mebius, Mebius, Meier, Messina, Motallebzadeh, Moussion, Moyron-Quiroz, Moyron-Quiroz, Muramatsu, Neyt, Nielsen, Nishikawa, Nzula, Ohl, Onder, Peske, Peters, Picker, Pitzalis, Randall, Randolph, Rangel-Moreno, Rangel-Moreno, Remark, Rennert, Roozendaal, Rosen, Ruddle, Sakaguchi, Sakai, Sawa, Scheu, Schmutz, Schneider, Schrama, Schrama, Scurr, Seleznik, Shields, Song, Stranford, Sun, Suzuki, Takatori, Teng, van de Pavert, van de Pavert, van de Pavert, Vermeij, Vondenhoff, Walter, Weinstein, Wengner, Winter, Yokota, Yoshida, Yoshida, Yoshida, Yu +151 morecore +5 more sourcesTertiary lymphoid structures in desmoplastic melanoma have increased lymphocyte density, lymphocyte proliferation, and immune cross talk with tumor when compared to non-desmoplastic melanomas
OncoImmunology, 2023 Tertiary lymphoid structures (TLS) are ectopic lymphoid structures that can arise in human cancers and are associated with improved overall survival (OS) and response to immune checkpoint blockade (ICB) in several cancers, including non-desmoplastic ...Nicole L. Edmonds, Sarah E Gradecki, Priya Katyal, Kevin T Lynch, Anne M Stowman, Alejandro A Gru, Victor H Engelhard, Craig L Slingluff, Ileana S. Mauldin +8 moredoaj +1 more sourceHyperactive gp130/STAT3-driven gastric tumourigenesis promotes submucosal tertiary lymphoid structure development [PDF]
, 2018 Tertiary lymphoid structures (TLSs) display phenotypic and functional characteristics of secondary lymphoid organs, and often develop in tissues affected by chronic inflammation, as well as in certain inflammation-associated cancers where they are ...Balic, Jesse J., Bhathal, Prithi S., D'Costa, Kimberley, Ferrero, Richard L., Gallimore, Awen M., Gao, Hugh, Hill, David, Jenkins, Brendan J., Jones, Gareth W., McLeod, Louise, Oshima, Hiroko, Oshima, Masanobu, Sievert, William, West, Alison, Yu, Liang +14 morecore +4 more sourcesTertiary lymphoid structures as local perpetuators of organ-specific immune injury: implication for lupus nephritis. [PDF]
, 2023 In response to inflammatory stimuli in conditions such as autoimmune disorders, infections and cancers, immune cells organize in nonlymphoid tissues, which resemble secondary lymphoid organs.He, Jing, Ishikawa, Tatsuya, Lai, Yupeng, Liu, Xingjiao, Nallapothula, Dhiraj, Rajkumar, Snehin, Singh, Ram, Wang, Meiying +7 morecore +1 more sourceRegulatory T cells infiltrate the tumor-induced tertiary lymphoïd structures and are associated with poor clinical outcome in NSCLC
Communications Biology, 2022 Regulatory T cells (Tregs) have similar immune profiles in tertiary lymphoid structures of lung cancer and non-TLS areas, with tumor-infiltrating Tregs found to inhibit the proliferation and cytokine secretion of CD4 + conventional T cells.Priyanka Devi-Marulkar, Solène Fastenackels, Pierre Karapentiantz, Jérémy Goc, Claire Germain, Hélène Kaplon, Samantha Knockaert, Daniel Olive, Marylou Panouillot, Pierre Validire, Diane Damotte, Marco Alifano, Juliette Murris, Sandrine Katsahian, Myriam Lawand, Marie-Caroline Dieu-Nosjean +15 moredoaj +1 more sourceInteractions between Type 1 Interferons and the Th17 Response in Tuberculosis: Lessons Learned from Autoimmune Diseases [PDF]
, 2017 textabstractThe classical paradigm of tuberculosis (TB) immunity, with a central protective role for Th1 responses and IFN-γ-stimulated cellular responses, has been challenged by unsatisfactory results of vaccine strategies aimed at enhancing Th1 ...Abhimanyu, Achkar, Afshar, Amarilyo, Ambrosi, Andersson, Antonelli, Arnason, Asano, Ashenafi, Askenase, Avci, Axtell, Axtell, Babudieri, Baccala, Bach, Baechler, Bafica, Bandaru, Barber, Barnes, Basile, Basile, Behar, Belkahla, Bennett, Benson, Berclaz, Berry, Bjornsdottir, Blanco, Blanco, Blomgran, Boer, Boniface, Boum, Braian, Brkic, Brkic, Brkic, Bulat-Kardum, Caccamo, Campbell, Canavan, Carmona-Rivera, Chen, Chen, Choi, Cliff, Cohen, Colditz, Collins, Conrady, Cooper, Coquery, Correa, Coscolla, Cowan, Craft, Crouse, Crow, Crow, Croxford, Cruz, Cunningham, Dalod, de Bruin, de Jong, de Paus, Decker, Demers, Deng, Desvignes, Dey, Di Paolo, Divangahi, Dolff, Dorhoi, Doz, Dragon, Du, Edwards, El-Behi, Elkayam, Elkington, Eruslanov, Eshleman, Eum, Fairweather, Farah, Farkas, Fejer, Feng, Fischer, Fleetwood, Francis, Francois, Freches, Fremond, Gagliani, Ganguly, Garcia-Romo, Gautier, Giosue, Giosue, Godfrey, Gonzalez-Juarrero, Gopal, Gopal, Gopal, Goriely, Goriely, Grainger, Griffin, Grogan, Grosset, Guarda, Guardigni, Guenova, Hedlund, Heidarnezhad, Higgins, Higgs, Hochrein, Hoeksema, Hoeve, Houben, Huebener, Hwang, Ifergan, Ireland, Ivashkiv, Jacob, Jayaraman, Jiao, Jin, Jones, Jones, Joosten, Joosten, Jurado, Kalinski, Kaminskaia, Kara, Kearney, Keller, Khader, Khader, Kim, Kim, Kirou, Kisich, Klose, Knaul, Kolb-Maurer, Korn, Kumar, Lande, Langrish, Langrish, Lazar-Molnar, Lazarus, Li, Liang, Lichtner, Lienard, Lindau, Linterman, Litinskiy, Liu, Lockhart, Longhi, Lood, Lopez, Lozza, Lu, Luan, Lubberts, Lyadova, Lyadova, Lyakh, MacKenzie, Maertzdorf, Maione, Manca, Manca, Manni, Manry, Mansoori, Manzanillo, Mao, Marin, Marin, Mariotti, Martin, Matsuoka, Mayer-Barber, Mayer-Barber, McNab, McNab, McNab, Merrill, Metcalfe, Midgley, Milano, Mishra, Mobley, Moguche, Monin, Mourik, Mueller, Munari, Mvubu, Nakayamada, Nandi, Napolitani, Navarra, Ndiaye, Ng, Niewold, Noster, Novikov, Nunnari, Okada, Okamoto Yoshida, Olobo, Ordway, Ottenhoff, O’Garra, Pai, Palmero, Pandey, Parkes, Parsa, Paulson, Peng, Perreau, Pers, Persson, Puthia, Rahman, Ramos-Kichik, Rangel Moreno, Rangel-Moreno, Raphael, Rasouli, Reboldi, Redford, Remoli, Repasy, Roberts, Ronnblom, Ronnblom, Roses, Rothchild, Rottenberg, Rovin, Russell, Sabbatani, Sage, Saiga, Sakai, Saraav, Sargentini, Scaffidi, Scapini, Schett, Schiffer, Schlitzer, Schreiber, Schreiber, Scordo, Scriba, Serezani, Shah, Shaler, Shapira, Shen, Shi, Shiomi, Shishikura, Shu, Sierra-Filardi, Silverpil, Simpson, Singh, Sjostrand, Slight, Sorgi, Spits, Stanley, Stephen-Victor, Stifter, Stohl, Strachan, Sutton, Swiecki, Szczucinski, Szeliga, Tada, Tall, Tameris, Teles, Telesca, Terawaki, Thien, Tian, Tian, Toossi, Torrado, Toubi, Trentini, Trinchieri, Tsai, Tsiganov, Tully, Ueno, Ulrichs, Umemura, Une, van Meijgaarden, van Nieuwenhuijze, Verreck, Verreck, Vincent, Vogt, von Scheidt, Wahren-Herlenius, Wang, Wassermann, Watson, Wilson, Wolf, Wong, Xu, Yamazaki, Yeremeev, Yoshimura, Zak, Zarogoulidis, Zhang, Zhang, Zhou, Zhou, Zitvogel, Zizzo, Zollars +347 morecore +4 more sourcesActivation of tyrosine kinases by mutation of the gatekeeper threonine. [PDF]
, 2008 Protein kinases targeted by small-molecule inhibitors develop resistance through mutation of the gatekeeper threonine residue of the active site. Here we show that the gatekeeper mutation in the cellular forms of c-ABL, c-SRC, platelet-derived growth ...Azam, Mohammad, Daley, George, Gray, Nathanael, KURIYAN, John, Seeliger, Markus +4 morecore +1 more source
