Results 1 to 10 of about 24,677 (191)
Development of fatty acid analogues with potent anabolic effects on bone in male mice [PDF]
Natural fatty acids are inhibitory to osteoclastogenesis, but only mildly so, as reported earlier by our and other groups. To improve the potency, we have synthesized two categories of analogues based on the backbone of saturated palmitic acid by ...
Jian-ming Lin +6 more
doaj +2 more sources
Exploring tetrazole chemistry: synthetic techniques, structure–activity relationship, and pharmacological insights in antimicrobial and anticancer therapy [PDF]
Tetrazoles are nitrogen-rich heterocycles that have attracted interest because of their numerous applications in pharmaceutical and medicinal chemistry.
Lalmohan Maji +9 more
doaj +2 more sources
First principle calculations were performed to investigate the electronic band structure, density of states, charge density and optical properties of 5-azido-1H-tetrazole.
Saleem Ayaz Khan, A.H. Reshak
doaj +2 more sources
Crystal structure and Hirshfeld surface analysis of 5-(3-nitro-1H-pyrazol-4-yl)-1H-tetrazole [PDF]
5-(3-Nitro-1H-pyrazol-4-yl)tetrazole, C4H3N7O2, was synthesized from cyanopyrazole via the Huisgen reaction. The asymmetric unit contains two molecules, each displaying notable torsion between the pyrazole and tetrazole systems.
Shannon E. Creegan +4 more
doaj +2 more sources
Synthesis of new multitope tetrazole-containing ligands
Drawing the experience of 5-phenyl- and 5-pyridyltetrazoles, it was shown that classical nitration-reduction methods in combination with typical alkylation reactions of tetrazole derivatives can be used to obtain multitopic polynuclear tetrazole ...
Evgeny Y. Grigoriev +5 more
doaj +1 more source
The synthesis of tetrazole-containing derivatives of chitosan, starch, and arabinogalactan was carried out by a sequence of reactions including cyanoethylation of polysaccharides and subsequent azidation of cyanoethyl derivatives.
Pokatilov Fedor A. +2 more
doaj +1 more source
Application of 1- and 2-propargyl-tetrazole in laser-ignitable energetic coordination compounds
1- and 2-Propargyl-tetrazole (1- and 2-PryTz) were synthesized by reaction of propargyl bromide with sodium tetrazolate and used as ligands in energetic coordination compounds (ECCs) and evaluated concerning their thermal and mechanical sensitivities ...
Simon M.J. Endraß +3 more
doaj +1 more source
A new series of tetrazole series of tetrazole tetrahydrobenzo[b]thiophene (10a-l) were synthesized and evaluated as antileishmanial activity and cytotoxicity of in vitro.
Sultan Pathan, Girdhar Pal Singh
doaj +1 more source
Heterocyclic skeleton (Azoles) and different energetic groups containing high performing explosives are highly emerged in recent years to meet the challenging requirements of energetic materials in both military and civilian applications with improved ...
Saira Manzoor +3 more
doaj +1 more source
Synthesis and Antileishmanial Activity of 1,2,4,5-Tetraoxanes against Leishmania donovani [PDF]
A chemically diverse range of novel tetraoxanes was synthesized and evaluated in vitro against intramacrophage amastigote forms of Leishmania donovani. All 15 tested tetraoxanes displayed activity, with IC50 values ranging from 2 to 45 µm.
Amado, Patrícia +5 more
core +1 more source

