Lead identification and structure-activity relationships of heteroarylpyrazole arylsulfonamides as allosteric CC-chemokine receptor 4 (CCR4) antagonists [PDF]
, 2014 A knowledge-based library of aryl 2,3-dichlorophenylsulfonamides was synthesised and screened as human CCR4 antagonists, in order to identify a suitable hit for the start of a lead-optimisation programme.
Copley, R.C.B. +4 more
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Synthesis, characterization and study of antibacterial activity of some novel tetrazole derivatives
Orbital: The Electronic Journal of Chemistry, 2011 This work aims at synthesizing novel tetrazole derivatives from phenothiazine. Phenothiazine is first converted into corresponding nitrile by reacting it with aldehyde, sodium metabisulphite and sodium cyanide.
Subramaniyan Arulmurugan +2 more
doaj +1 more source
Hexaaquazinc(II) dinitrate bis[5-(pyridinium-3-yl)tetrazol-1-ide] [PDF]
, 2018 Indexación: Scopus.Funding for this research was provided by: Fondecyt Regular (award No. 1151527); Proyecto REDES ETAPA INICIAL, Convocatoria 2017 (award No. REDI170423); Millennium Institute for Research in Optics (MIRO); Basal USA (award No.
Chi-Duran, I. +4 more
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Synthesis of 4-[10H-Phenothiazin-10-yl(1H-tetrazol-5-yl)-methyl]phenol
Molbank, 2009 This present work aims at synthesizing a novel tetrazole from phenothiazine. Phenothiazine is converted into a nitrile by reacting it with 4-hydroxybenzaldehyde, sodium metabisulphite and sodium cyanide. The nitrile on treatment with NaN3/DMF yielded the
Bathey R. Venkatraman, Helen P. Kavitha
doaj +1 more source
Nitrene-carbene-carbene rearrangement. photolysis and thermolysis of tetrazolo[5,1- a ]phthalazine with formation of 1-phthalazinylnitrene, o-cyanophenylcarbene, and phenylcyanocarbene [PDF]
, 2012 1-Azidophthalazine 9A is generated in trace amount by mild FVT of tetrazolo[5,1-a]phthalazine 9T and is observable by its absorption at 2121 cm-1 in the Ar matrix IR spectrum.
Mora de Sambricio, Javier +5 more
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Chemical investigation of light induced DNA bipyrimidine damage and repair [PDF]
, 2011 In all organisms, genetic information is stored in DNA and RNA. Both of these macromolecules are damaged by many exogenous and endogenous events, with UV irradiation being one of the major sources of damage.
Carell, Thomas +2 more
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1-(2,2-Diphenylethyl)-1H-tetrazole
Acta Crystallographica Section E, 2012 The crystal structure of the title compound, C15H14N4, contains chains of coplanar tetrazole rings with the chain direction along b. These are formed through weak hydrogen bonds, donated by the tetrazole H atoms and by one of the H atoms of the methylene
Myrvete Tafili-Kryeziu +3 more
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Low temperature matrix-isolation and solid state vibrational spectra of tetrazole [PDF]
, 2001 Infrared spectra of tetrazole (CN isolated in an argon matrix (T \10 K) and in the solid state (at room 4H2) temperature) were investigated. In the crystalline phase, tetrazole exists in its 1H-tautomeric form and new assignments of the vibrational ...
Bugalho, Susana C. S. +3 more
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Direct synthesis of anomeric tetrazolyl iminosugars from sugar-derived lactams
Beilstein Journal of Organic Chemistry, 2021 Herein we present the direct asymmetric synthesis of tetrazole-functionalized 1-deoxynojirimycin derivatives from simple sugars via a Schwartz’s reagent-mediated reductive amide functionalization followed by a variant of the Ugi–azide multicomponent ...
Michał M. Więcław, Bartłomiej Furman
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Regiospecific synthesis of N2-aryl 1,2,3-triazoles from 2,5-disubstituted tetrazoles via photochemically generated nitrile imine intermediates [PDF]
, 2014 The synthesis of N2-aryl 1,2,3-triazoles from 2,5-disubstituted tetrazoles was achieved under photochemical conditions. This simple and mild one-step reaction provides regiospecific access to 2,4,5-substituted 1,2,3-triazoles via a nitrile imine ...
Harris, Robert +2 more
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