Results 31 to 40 of about 319,332 (247)
Journal of Experimental Medicine, 1993 The effects exerted on the in vitro development of antigen-specific T cell lines and T cell clones by addition or neutralization of interleukin 12 (IL-12) in lymphocyte bulk culture were examined.
R. Manetti +6 more
semanticscholar +1 more source
Th1/Th2 in aspergillosis [PDF]
Medical Mycology, 2006 The outcome of the Th1/Th2 balance is a critical determinant of the outcome in invasive aspergillosis. The innate immune system encounters the pathogen first. Dendritic cells (DC) appear to be the critical fulcrum at the intersection of the innate immune system, and which receptors are engaged, particularly which Toll-like receptors are triggered by ...
openaire +2 more sources
Role of CD20+T lymphocytes in the pathogenesis of multiple sclerosis
Медицинская иммунологияCD3+CD20+T lymphocytes are a population of T cells that, along with standard T cell markers, express the atypical membrane molecule CD20 (a traditional B cell marker).
N. S. Glebezdina
doaj +1 more source
Медицинская иммунология, 2014 . Over last years, huge efforts are made in order to improve analytic techniques for T lymphocyte subpopulations. Appropriate studies on T-helper cells are also subject to extensive research.
S. V. Khaidukov, A. V. Zurochka
doaj +1 more source
CYTOKINE CONTENTS IN Th1- AND Th17-TYPE LYMPHOCYTES IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Медицинская иммунология, 2016 We studied cytokine profiles relevant to the Th1 and Th17 modes of immune response in 116 patients with mild, moderate and severe chronic obstructive pulmonary disease (COPD).
E. G. Lobanova +2 more
doaj +1 more source
Cell Death Discovery, 2023 Type 1 T helper (Th1) cells generate an efficient antitumor immune response in multiple malignancies. The functions of Th1 cells in malignant ascites (MA) have not been elucidated.
Chang Liu +7 more
doaj +1 more source
Frontiers in Microbiology, 2022 AimsMicroRNA-451a (miR-451a) regulates Th1/Th2 cell differentiation, inflammation, and septic organ injury in several experiments. Therefore, the present study aimed to explore the inter-correlation of miR-451a with the Th1/Th2 ratio, and their ...
Feng Geng, Wei Liu, Li Yu
doaj +1 more source
Saikosaponin A Inhibits Breast Cancer by Regulating Th1/Th2 Balance
Frontiers in Pharmacology, 2019 Saikosaponin A (SSa) is isolated from the dried root of Radix Bupleuri, an herb widely used in traditional Chinese medicine, exerting antitumor activities.
Xin Zhao +8 more
semanticscholar +1 more source
TIGIT signaling restores suppressor function of Th1 Tregs.
JCI Insight, 2019 Th1 Tregs are characterized by the acquisition of proinflammatory cytokine secretion and reduced suppressor activity. Th1 Tregs are found at increased frequency in autoimmune diseases, including type 1 diabetes and multiple sclerosis (MS).
Liliana E. Lucca +5 more
semanticscholar +1 more source
Further Checkpoints in Th1 Development [PDF]
Immunity, 2002 Tight control of Th1 immunity is essential to prevent immunopathology. Central to control of the IFN-gamma gene is the transcription factor T-bet, whose induction is Stat-1 dependent. IL-12 is dominant in directing Th1 development, while synergizing with IL-18 for IFNgamma production from differentiated Th1 cells.
Robinson, Douglas S, O'Garra, Anne
openaire +2 more sources