Results 261 to 270 of about 260,137 (386)

NLRP3 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis by Mediating Th1 and Th17 Responses

, 2020
Denis Gris, Zhengmao Ye, Heather A. Iocca, Haitao Wen, Robin R. Craven, Pavel Gris, Max T. Huang, Monika Schneider, Stephen D. Miller, Jenny P.‐Y. Ting   +9 more
openalex   +1 more source

Exploring the Link Between Psoriasis and Genetic Predictors of Cardiac Magnetic Resonance Traits: A Bidirectional Mendelian Randomization Study

iNew Medicine, EarlyView.
ABSTRACT Psoriasis is a chronic autoimmune disease characterized by systemic inflammation and skin involvement, affecting millions of individuals worldwide. However, few studies have evaluated whether psoriasis and cardiac magnetic resonance imaging (CMR) traits share a common genetic basis.
Junlin Yang, Pengzhan Yin, Shutian An, Zhanglei Li, Yewen Jiang, Jun Wang, Yongqiang Yu, Ren Zhao, Xiaohu Li   +8 more
wiley   +1 more source

<i>Fusobacterium nucleatum</i> drives CD40-mediated dendritic cell activation and Th17/Treg imbalance to exacerbate intestinal inflammation in Crohn's disease. [PDF]

Front Immunol
Wang M, Sun J, Yu J, Wang J, Xu C, Ma J, Zhang H.   +6 more
europepmc   +1 more source

Anti‐CD47 antibody‐decorated and cisplatin‐containing mesoporous silica nanoparticles for targeted chemoimmunotherapy of colorectal cancer in a patient‐derived organoids xenograft model

Interdisciplinary Medicine, EarlyView.
Upon targeted binding to CD47‐overexpressing colorectal cancer (CRC) cells, the nanoparticles disrupt signal regulatory protein α‐CD47 signaling and allow for the restoration of innate immune response by tumor‐associated macrophages (TAMs) against CRC.
Albert Yu, Yibo Hou, Kaibin Huang, Xucan Gao, Rong Zeng, Chaowei Zhu, Chunhui Sun, Guocai Wang, Lei Ye, Shaohua Ma, Tian Meng, Bing Guo, Yubo Zhang, Xiaoyong Dai   +13 more
wiley   +1 more source

The critical role of Th17 cells and IL-17A in autoimmune and inflammation-associated neurological diseases: mechanisms and therapeutic perspectives. [PDF]

Front Immunol
Xu Lou I, Zhou H, Wan H.
europepmc   +1 more source

Down-regulation of Gfi-1 expression by TGF-β is important for differentiation of Th17 and CD103+ inducible regulatory T cells [PDF]

, 2009
Jinfang Zhu, Todd S. Davidson, Gang Wei, Dragana Janković, Kairong Cui, Dustin E. Schones, Liying Guo, Keji Zhao, Ethan M. Shevach, William E. Paul   +9 more
openalex   +1 more source

Inflammatory bowel disease and metabolic reprogramming: From pathological mechanisms to targeted interventions

Interdisciplinary Medicine, EarlyView.
This review explores the role of metabolic reprogramming in inflammatory bowel disease (IBD) by focusing on immune and epithelial cell metabolism, microbial metabolites, and their impact on inflammation. It discusses emerging metabolic therapies and emphasizes the importance of personalized microbiota‐targeted approaches to improve clinical outcomes in
Zemin Tian, Yinde Huang, Ying Wang, Chenyu Zhao, Zhaokai Zhou, Hua Yang, Yuan Qiu   +6 more
wiley   +1 more source

Relationship Between Group 3 Innate Lymphoid Cells and Th17 in Human Nasopharynx-Associated Lymphoid Tissue and the Association With Pneumococcal Carriage. [PDF]

J Infect Dis
Zaki L, Xu R, Sharma R, Krishnan M, Leong S, Derbyshire S, Marks I, Bagnoli F, McNamara PS, French N, Zhang Q.   +10 more
europepmc   +1 more source

The Fos-related antigen 1–JUNB/activator protein 1 transcription complex, a downstream target of signal transducer and activator of transcription 3, induces T helper 17 differentiation and promotes experimental autoimmune arthritis [PDF]

, 2017
et al,, Kim, Woo Kyung
core   +1 more source

Reference Intervals for Lymphocyte Subpopulations in Healthy Chinese Han Adults: A Single‐Center Study

Journal of Clinical Laboratory Analysis, EarlyView.
Correlation matrix analysis of lymphocyte parameters. The correlation matrix showed the positive (red) or negative (blue) correlation of two parameters; the color intensity reflected the correlation coefficient. Conducting lymphocyte testing in health management can help monitor immune status, evaluate health risks, analyze pathogenesis of diseases ...
An‐Na Jiang, Lin‐Zi Miao, Yan Gong, Ran You, Yao Lu, Chen‐Xue Qu   +5 more
wiley   +1 more source